Activities in Family	Trans-sialidase (EC 2.4.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-); Kdo hydrolase (EC 3.2.1.124); Exo-α-sialidase (EC 3.2.1.18); Anhydrosialidase (EC 4.2.2.15);
Mechanism	Retaining e
Clan	GH-E
3D Structure Status	6-fold β-propeller
Catalytic Nucleophile/Base	Tyr+Glu
Catalytic Proton Donor	Not known
External resources	CAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)	MEGAZYME;
Statistics	GenBank accession (11188); Uniprot accession (128); PDB accession (186); 3D entries (29); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
B0909_19345		Rhizobium rhizogenes K599	AQS64435.1
Arad_8793		Rhizobium rhizogenes K84	ACM29979.1
D4A92_06640		Rhizobium rosettiformans MAE2-X	QRF51134.1
J3P73_33155		Rhizobium ruizarguesonis NZLR24	QSZ04888.1
BSO17_25920		Rhizobium ruizarguesonis RCAM 1026	UED34000.1
RlegTA1_30335		Rhizobium ruizarguesonis TA1	UFW97868.1
ISN39_25755		Rhizobium sp. 007	QPB22962.1
ACO34A_27720		Rhizobium sp. ACO-34A	ATN37563.1
F2982_22460		Rhizobium sp. BG4	QRM46169.1
F3Y33_20895		Rhizobium sp. BG6	QRM51772.1
QMO80_006403		Rhizobium sp. BT03	WHO77192.1
MF410_24190		Rhizobium sp. C104	ULJ80896.1
QA644_28330		Rhizobium sp. CC1099	WFU89947.1
neuraminidase		Rhizobium sp. IE4771	AIC31579.1
BN877_II1047		Rhizobium sp. IRBG74	CDI10839.1
FE844_033525		Rhizobium sp. JKLM13E	QKK34489.1
FFM81_028340		Rhizobium sp. JKLM19E	QKK27150.1
MHI61_02170		Rhizobium sp. K102	ULR42334.1
RKHAN_03264		Rhizobium sp. Khangiran2	CAD6616965.1
neuraminidase		Rhizobium sp. Kim5	ARQ62321.1
neuraminidase		Rhizobium sp. N113	ANL25351.1
neuraminidase		Rhizobium sp. N1314	ANL18053.1
neuraminidase		Rhizobium sp. N1341	ANL13367.1
neuraminidase		Rhizobium sp. N324	ANM13180.1
neuraminidase		Rhizobium sp. N541	ANM19578.1
neuraminidase		Rhizobium sp. N621	ANL01075.1
neuraminidase		Rhizobium sp. N6212	ANK95023.1
neuraminidase		Rhizobium sp. N731	ANK87807.1
neuraminidase		Rhizobium sp. N741	ANM44192.1
neuraminidase		Rhizobium sp. N871	ANM38040.1
neuraminidase		Rhizobium sp. N941	ANM25963.1
J7U39_30475		Rhizobium sp. NLR16a	QTV00778.1
neuraminidase		Rhizobium sp. NXC14	ARO33709.1
J3O30_30610		Rhizobium sp. NZLR1	QSZ24948.1
NE852_30960		Rhizobium sp. Pop5	UVD60200.1
REQ54_01966		Rhizobium sp. Q54	CAD6419382.1
BA939_21445		Rhizobium sp. S41	ANV26489.1
IM739_20455		Rhizobium sp. SL42	UJW77438.1
QTJ18_04150		Rhizobium sp. SSA_523 SSA5.23	WKC22338.1
LPB79_10715		Rhizobium sp. T136	UFS82757.1
WGT02_00070		Rhizobium sp. T1470	WXL45974.1
FVA81_12295		Rhizobium sp. WL3	QEE45339.1
KQ933_15600		Rhizobium sp. WYJ-E13	QWW67034.1
BLX90_18320		Rhizobium sp. Y9	AUC12238.1
BTN45_19930		Rhizobium sp. ZX09	QSZ59447.1
N2599_27525		Rhizobium sullae WSM1592	UWU16605.1
E0W69_015090		Rhizosphaericola mali B3-10	QES90995.1
E0W69_008005		Rhizosphaericola mali B3-10	QES88603.1
CS053_12530		Rhodanobacter glycinis T01E-68	QEE25224.1
GQ464_017055		Rhodocaloribacter litoris ISCAR-4553	QXD15092.1
A3L23_01204		Rhodococcus fascians D188	AMY52555.1
JWS14_25445		Rhodococcus koreensis R85	QSE85316.1
HJ581_0025335		Rhodococcus opacus 3D	WKN56828.1
ROP_47090		Rhodococcus opacus B4	BAH52956.1
FXW36_27515		Rhodococcus opacus DSM 44186	QZS53958.1
ONE62_04920		Rhodococcus opacus G13	UZG56664.1
K2Z90_001057		Rhodococcus opacus PD630	UDG98241.1
Pd630_LPD01108		Rhodococcus opacus PD630	AHK28342.1
MOO23_17895		Rhodococcus opacus S8	UNM97665.1
Q5707_04770		Rhodococcus opacus VOC-14	WLF48322.1
NY08_3011		Rhodococcus sp. B7740	AJW41021.1
OYT95_13705		Rhodococcus sp. JS3073	WAM17622.1
A3Q40_00702		Rhodococcus sp. PBTS 1	AMY18110.1
I1A62_32885		Rhodococcus sp. USK10	QYB01996.1
FND50_05890		Rhodococcus sp. WB9	QDQ90364.1
ICHIAU1_16770		Rhodocyclaceae bacterium ICHIAU1	BBU69394.1
ICHIJ1_13430		Rhodocyclaceae bacterium ICHIJ1	BBU71424.1
GXP67_30855		Rhodocytophaga rosea 172606-1	QHT70737.1
GXP67_17365		Rhodocytophaga rosea 172606-1	QHT72060.1
neuraminidase		Rhodocytophaga rosea 172606-1	QHT67545.1
EXZ61_17450		Rhodoferax aquaticus Gr-4	QDL55811.1
RS694_16465		Rhodoferax saidenbachensis DSM 22694	APW43968.1
HZ993_20350		Rhodoferax sp. AJA081-3	QTN27590.1
HTY51_13740		Rhodoferax sp. BAB1	QKO22864.1
MIZ03_3590		Rhodoferax sp. MIZ03	BCO28680.1
RAN89_06905		Rhodoferax sp. TBRC 17307	WNO06153.1
RB3006		Rhodopirellula baltica SH 1	CAD72956.1 NP_865272.1
RB8895 (NanH)		Rhodopirellula baltica SH 1	CAD75983.1 NP_868606.1
RB3353		Rhodopirellula baltica SH 1	CAD73141.1 NP_865457.1
RB1257		Rhodopirellula baltica SH 1	CAD71993.1
RB5143		Rhodopirellula baltica SH 1	CAD78312.1
RB8501		Rhodopirellula baltica SH 1	CAD78672.1
RB11055		Rhodopirellula baltica SH 1	CAD77137.1
PSR62_00830		Rhodopirellula sp. P2	WDQ17112.1
PSR62_06695		Rhodopirellula sp. P2	WDQ18232.1
AWN76_001570		Rhodothermaceae bacterium RA	ARA91982.1
AWN76_004200		Rhodothermaceae bacterium RA	ARA92447.1
RHOA_5154		Rhodovastum atsumiense G2-11	CAH2603906.1
RHOA_4446		Rhodovastum atsumiense G2-11	CAH2603157.1
B5V46_14810		Rhodovulum sp. MB263	ARC89782.1
A3305_00130		Rickettsia amblyommatis	ARD87062.1
AL573_05330		Rickettsia amblyommatis str. Ac37	ALA62014.1
MCE_05845		Rickettsia amblyommatis str. GAT-30V	AFC70011.1
A3306_00245		Rickettsia bellii	ARD85733.1
RCA_02435		Rickettsia canadensis str. CA410	AFB21060.1
A1E_02610		Rickettsia canadensis str. McKiel	ABV73466.1
NBT09_06045		Rickettsia conorii subsp. raoultii BIME	URW77548.1
NBT09_07425 (fragment)		Rickettsia conorii subsp. raoultii BIME	URW77783.1
RRIM16_03300 (fragment)		Rickettsia conorii subsp. raoultii IM16	APZ30646.1
JRD95_00766		Rickettsia parkeri Black Gap	QWB86712.1
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