Glycoside Hydrolase Family 31

Activities in Familyα-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); α-mannosidase (EC 3.2.1.24); α-1,3-glucosidase (EC 3.2.1.84); sucrase-isomaltase (EC 3.2.1.48) (EC 3.2.1.10); α-xylosidase (EC 3.2.1.177); α-glucan lyase (EC 4.2.2.13); isomaltosyltransferase (EC 2.4.1.-); oligosaccharide α-1,4-glucosyltransferase (EC 2.4.1.161); sulfoquinovosidase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-D
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
External resourcesCAZypedia; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (7388); Uniprot accession (1019); PDB accession (97); 3D entries (21); cryst (0)
All (6820) Archaea (87) Bacteria (6037) Eukaryota (687) unclassified (9) Structure (21) Characterized (123)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF (fragment)   Fernaldella fimetaria AGI52404.1    
 α-glucosidase (fragment)   Fusarium fujikuroi BAF91419.1 A8R5X7  
 FFUJ_13167   Fusarium fujikuroi IMI 58289 CCT66990.1    
 FFUJ_05374   Fusarium fujikuroi IMI 58289 CCT69486.1    
 FFUJ_06119   Fusarium fujikuroi IMI 58289 CCT70171.1    
 FFUJ_06320   Fusarium fujikuroi IMI 58289 CCT70355.1    
 FFUJ_06693   Fusarium fujikuroi IMI 58289 CCT70700.1    
 FFUJ_10405   Fusarium fujikuroi IMI 58289 CCT74357.1    
 FFUJ_02282   Fusarium fujikuroi IMI 58289 CCT65346.1    
 FFUJ_04183   Fusarium fujikuroi IMI 58289 CCT64583.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF87825.1    
 unnamed protein product   Fusarium graminearum PH-1 SCB65060.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF85426.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF76992.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF77226.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF77613.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF78272.1    
 FGRAMPH1_01T00389   Fusarium graminearum PH-1 SCB63990.1
CEF71994.1
   
 sucrase-isomaltase (fragment)   Gallus gallus CAA70154.1 O42389  
 GH31-1   Gastrophysa viridula AHH86054.1    
 ORF (fragment)   Gonometa rufobrunnea AGI52410.1    
 α-1,4-glucan lyase isozyme 1 (GLq1;Ag111) 4.2.2.13 Gracilariopsis lemaneiformis CAB51910.1
AAR66623.1
ABA16064.1
Q9STC1 2X2H[A,B,C,D]
2X2I[A,B,C,D]
2X2J[A,B,C,D]
4AMW[A,B,C,D]
4AMX[A,B,C,D]
 α-1,4-glucan lyase isozyme 2 (GLq2;Ag112) 4.2.2.13 Gracilariopsis lemaneiformis CAB51911.1
AAR66624.1
ABA16065.1
Q9STC0  
 α-1,4-glucan lyase isozyme 4 (GLs1;Ag114) 4.2.2.13 Gracilariopsis lemaneiformis CAB51909.1
AAP61561.1
ABA16068.1
Q9STC2  
 α-1,4-glucan lyase isozyme 5 (GLs2;Ag115) (partial) (fragment) 4.2.2.13 Gracilariopsis lemaneiformis CAB51913.1
AAP61562.1
ABA16069.1
Q9STB8  
 α-1,4-glucan lyase isozyme 3 (GLq3;Ag113) (fragment)   Gracilariopsis lemaneiformis CAB51912.1 Q9STB9  
 α-glucosidase (HdAgl1;HdAgl) 3.2.1.20 Haliotis discus hannai BAN67474.1    
 glucosidase (fragment)   Helicoverpa armigera GR ADF43509.1 D5G3I0  
 ORF (fragment)   Heteranassa fraterna AGI52401.1    
 α-glucosidase A (GAA) (lysosomal) 3.2.1.20 Homo sapiens CAA68763.1
AAA52506.1
AAB33842.1
AAH40431.1
ABI53718.1
ACM80396.1
ACM84029.1
BAH13042.1
CAA38907.1
CAA68764.1
CAC12967.1
CAE85448.1
NP_000143.1
P10253
P10253
Q8IWE7
5KZW[A]
5KZX[A]
 α-glucosidase II (GanAB;G2AN;KIAA0088 ) 3.2.1.20
3.2.1.84
Homo sapiens AAF66685.1
AAH17433.2
AAH17435.2
AAH65266.1
ACJ13667.1
BAA07642.1
BAG58624.1
BAG58692.1
BAG61688.1
BAG63965.1
CAA04006.1
XP_043268.1
Q14697
Q14697
 
 maltase-glucoamylase (MgaM;Mga;MGAML) 3.2.1.20 Homo sapiens AAC39568.2
AAI20873.1
AAL83560.1
NP_004659.1
O43451
Q8TE24
3TON[A,B]
3TOP[A,B]
 maltase-glucoamylase (MgaM;Mga;MGAML) 3.2.1.20 Homo sapiens AAC39568.2
AAI20873.1
AAL83560.1
AAP21875.1
NP_004659.1
O43451
Q86UM5
Q8TE24
2QLY[A]
2QMJ[A]
3CTT[A]
3L4T[A]
3L4U[A]
3L4V[A]
3L4W[A]
3L4X[A]
3L4Y[A]
3L4Z[A]
 sucrase-isomaltase (SI) 3.2.1.10
3.2.1.48
Homo sapiens AAT18166.1
AAI15035.1
AAI16453.1
AAI16454.1
AAI32835.1
AAI32861.1
AAT19036.1
ABH87017.1
ACM85129.1
ACP58672.1
CAA45140.1
NP_001032.1
P14410  
 sucrase-isomaltase (SI) 3.2.1.10
3.2.1.48
Homo sapiens AAT18166.1
AAA60551.1
AAI15035.1
AAI16453.1
AAI16454.1
AAI32835.1
AAI32861.1
AAT19036.1
ABH87017.1
ACM85129.1
ACP58672.1
CAA45140.1
NP_001032.1
P14410 3LPO[A,B,C,D]
3LPP[A,B,C,D]
 unnamed protein product   Homo sapiens BAD18495.1 Q6ZN80  
 KIAA1161 (MGC:87539)   Homo sapiens AAH70098.1
AAI10494.1
BAA86475.2
CAI15965.1
Q6NSJ0
Q9ULQ9
 
 GanC (FLJ00088)   Homo sapiens AAN74756.1
AAH59406.1
AAH93833.1
AAI12052.1
AAN74755.1
AAN74757.1
AAN74758.1
AAO14993.1
BAB84863.1
BAB84863.2
NP_937784.2
Q8TET4  
 pseudogene (fragment)   Homo sapiens XP_051350.1
AAI11974.1
AAI11976.1
XP_051350.2
Q2M2H8  
 α-glucosidase 3.2.1.20 Hordeum vulgare AAB02985.1
AAX04432.1
Q43763  
 α-glucosidase (Agl1)   Hordeum vulgare subsp. spontaneum ACZ37245.1 D1MDW3  
 α-glucosidase (Agl1)   Hordeum vulgare subsp. spontaneum ACZ37246.1 D1MDW4  
 α-glucosidase (Agl2)   Hordeum vulgare subsp. vulgare BAG72143.1    
 Agl3   Hordeum vulgare subsp. vulgare BAG72144.1    
 Agl4   Hordeum vulgare subsp. vulgare BAG72145.1    
 predicted protein   Hordeum vulgare subsp. vulgare BAK05419.1    
 predicted protein   Hordeum vulgare subsp. vulgare BAJ97257.1    
 α-glucosidase (Agl1;Agl97) 3.2.1.20 Hordeum vulgare subsp. vulgare AAF76254.1
ACZ37234.1
ACZ37244.1
ACZ37249.1
BAJ89297.1
D1MDV2
Q9LLY2
 
 ORF   Hypocrella siamensis MTCC 10142 ANH56431.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56461.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56510.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56427.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56499.1    
 ORF (Sp15)   Ictalurus punctatus AHH38618.1    
 ORF (GanaB)   Ictalurus punctatus AHH38955.1    
 KAFR_0G02180 (Kafr0g02180)   Kazachstania africana CBS 2517 CCF59252.1    
 KNAG_0M00730 (Knag0m00730)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK72926.1    
 KLLA0F09735g   Kluyveromyces lactis NRRL Y-1140 CAG98230.1 Q6CKL7  
 KLMA_20272   Kluyveromyces marxianus DMKU3-1042 BAO38730.1    
 KMAR_20262   Kluyveromyces marxianus NBRC 1777 BAP70274.1    
 ATY40_BA7502369 (Rot2)   Komagataella pastoris ATCC 28485 ANZ75517.1    
 AT249_GQ6700850 (Rot2)   Komagataella phaffii ATCC 76273 AOA62140.1    
 PP7435_Chr2-0493 (Rot2)   Komagataella phaffii CBS 7435 CCA38181.1    
 PAS_chr2-1_0778   Komagataella phaffii GS115 CAY69434.1
AOA67561.1
C4R1R0  
 KLTH0H06336g   Lachancea thermotolerans CBS 6340 CAR30293.1    
 LbrM18_V2.0110   Leishmania braziliensis MHOM/BR/75/M2904 CAM37985.1 A4H9B4  
 LbrM35_V2.4340   Leishmania braziliensis MHOM/BR/75/M2904 CAM44186.1 A4HPS8  
 LDBPK_180090   Leishmania donovani BPK282A1 CBZ33316.1    
 LDBPK_364300   Leishmania donovani BPK282A1 CBZ38867.1    
 LinJ18.0090   Leishmania infantum JPCM5 CAM67062.1    
 LinJ36.7060   Leishmania infantum JPCM5 CAM73155.1    
 LmjF18.0090   Leishmania major strain Friedlin CAJ03446.1 Q4QE33  
 LmjF36.4100   Leishmania major strain Friedlin CAJ09376.1 Q4Q105  
 LMXM_18_0090   Leishmania mexicana MHOM/GT/2001/U1103 CBZ25517.1    
 LMXM_36_4100   Leishmania mexicana MHOM/GT/2001/U1103 CBZ26267.1    
 LPMP_180090   Leishmania panamensis MHOM/PA/94/PSC-1 AIN97190.1    
 LPMP_354210   Leishmania panamensis MHOM/PA/94/PSC-1 AIO02554.1    
 GH31-1   Leptinotarsa decemlineata AHH86055.1    
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX96756.1 E4ZZG1  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX97527.1 E5A171  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX98711.1 E5A513  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX99019.1 E5A5X4  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX99068.1 E5A623  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY00749.1 E5AAQ8  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY01502.1 E5AE63  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY00488.1 E5A9Z7  
 ORF (fragment)   Lesmone griseipennis AGI52402.1    
 LRAMOSA04990   Lichtheimia ramosa CDS12806.1    
 LRAMOSA05653   Lichtheimia ramosa CDS13477.1    
 LRAMOSA05693   Lichtheimia ramosa CDS13517.1    
 LRAMOSA02154   Lichtheimia ramosa CDS08206.1    
 LRAMOSA09753   Lichtheimia ramosa CDS08390.1    
 α-glucosidase 3.2.1.20 Litopenaeus vannamei CAB85963.1 Q9NFY8  
 α-glucosidase 1   Lygus lineolaris AHG54243.1    
 α-glucosidase 2   Lygus lineolaris AHG54244.1    
 α-glucosidase 3   Lygus lineolaris AHG54245.1    
 β-glucosidase 2   Lygus lineolaris AHG54238.1    
 ORF (fragment)   Macaca fascicularis BAB69731.1 Q95LM6  
 ORF   Macaca fascicularis BAE01938.1
BAE90752.1
Q4R4N7  
 unnamed protein product (fragment)   Macaca fascicularis BAE89513.1    
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