Known Activities	α-glucosidase (EC 3.2.1.20); α-1,3-glucosidase (EC 3.2.1.84); sucrase-isomaltase (EC 3.2.1.48) (EC 3.2.1.10); α-xylosidase (EC 3.2.1.177); α-glucan lyase (EC 4.2.2.13); isomaltosyltransferase (EC 2.4.1.-).
Mechanism	Retaining
Clan	GH-D
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Asp
Catalytic Proton Donor	Asp
External resources	CAZypedia; InterPro; PFAM; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME;
Statistics	GenBank accession (1874); Uniprot accession (949); PDB accession (38); 3D entries (7); cryst (0)

Archaea
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
α-glucosidase (MalA;Sso1_0793)	3.2.1.20	Sulfolobus solfataricus 98/2	AAC38215.1 ACX91047.1 AET42970.1	D0KQM8 O59645.1	2G3M[A,B,C,D,E,F] 2G3N[A,B,C,D,E,F]
Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
α-xylosidase 31A (CJA_2706) (Xyl31A)	3.2.1.177	Cellvibrio japonicus Ueda107	ACE86259.1	B3PBD9	2XVG[A] 2XVK[A] 2XVL[A]
α-xylosidase (YicI;b3656)	3.2.1.177	Escherichia coli K-12 MG1655	AAA62009.1 AAC76680.1 NP_418113.1	P31434.2	1WE5[A,B,C,D,E,F] 1XSI[A,B,C,D,E,F] 1XSJ[A,B,C,D,E,F] 1XSK[A,B,C,D,E,F] 2F2H[A,B,C,D,E,F]
α-glucosidase / maltase-glucoamylase (RUMOBE_03919)	3.2.1.20	Ruminococcus obeum ATCC 29174	ZP_01966167.1	A5ZY13	3FFJ[A,B] 3M46[A,B] 3M6D[A,B] 3MKK[A,B] 3N04[A,B] 3NQQ[A,B] 3NSX[A,B] 3NUK[A,B] 3NXM[A,B,C,D] 3PHA[A,B,C,D] 3POC[A,B]
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
α-1,4-glucan lyase isozyme 1 (GLq1;Ag111)	4.2.2.13	Gracilariopsis lemaneiformis	AAR66623.1 ABA16064.1 CAB51910.1	Q9STC1	2X2H[A,B,C,D] 2X2I[A,B,C,D] 2X2J[A,B,C,D]
maltase-glucoamylase (MgaM;Mga;MGAML)	3.2.1.20	Homo sapiens	AAC39568.2 AAI20873.1 AAL83560.1 NP_004659.1	O43451.4 Q8TE24	3TON[A,B] 3TOP[A,B]
maltase-glucoamylase (MgaM;Mga;MGAML)	3.2.1.20	Homo sapiens	AAC39568.2 AAI20873.1 AAL83560.1 AAP21875.1 NP_004659.1	O43451.4 Q86UM5 Q8TE24	2QLY[A] 2QMJ[A] 3CTT[A] 3L4T[A] 3L4U[A] 3L4V[A] 3L4W[A] 3L4X[A] 3L4Y[A] 3L4Z[A]
sucrase-isomaltase (SI)	3.2.1.10 3.2.1.48	Homo sapiens	AAA60551.1 AAI15035.1 AAI16453.1 AAI16454.1 AAI32835.1 AAI32861.1 AAT18166.1 AAT19036.1 ABH87017.1 ACM85129.1 ACP58672.1 CAA45140.1 NP_001032.1	P14410.4	3LPO[A,B,C,D] 3LPP[A,B,C,D]

Last update: 2012-01-31 © Copyright 1998-2012
AFMB - CNRS - Universités Aix-Marseille I & II