Glycoside Hydrolase Family 31

Activities in Familyα-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); α-mannosidase (EC 3.2.1.24); α-1,3-glucosidase (EC 3.2.1.84); sucrase-isomaltase (EC 3.2.1.48) (EC 3.2.1.10); α-xylosidase (EC 3.2.1.177); α-glucan lyase (EC 4.2.2.13); isomaltosyltransferase (EC 2.4.1.-); oligosaccharide α-1,4-glucosyltransferase (EC 2.4.1.161); sulfoquinovosidase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-D
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
External resourcesCAZypedia; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (7621); Uniprot accession (1017); PDB accession (102); 3D entries (21); cryst (0)
All (7056) Archaea (87) Bacteria (6257) Eukaryota (703) unclassified (9) Structure (21) Characterized (123)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF   Macaca fascicularis BAB39324.1 Q9BE70  
 neutral α-glucosidase C (GanC)   Macaca mulatta AFE66444.1    
 neutral α-glucosidase AB isoform 3 (GanaB)   Macaca mulatta AFE77355.1
AFI34679.1
   
 neutral α-glucosidase AB isoform 2 (GanaB)   Macaca mulatta AFE77354.1
AFI34680.1
   
 lysosomal α-glucosidase preproprotein (GaA)   Macaca mulatta AFE67011.1    
 ORF (fragment)   Macaca mulatta AFE73358.1    
 ORF (fragment)   Macaca mulatta AFE74543.1    
 ORF (fragment)   Macaca mulatta AFE72041.1    
 ORF   Macaca mulatta AFJ71910.1    
 MG09757.4   Magnaporthe oryzae 70-15 XP_364912.1 G4NA29  
 MG02096.4   Magnaporthe oryzae 70-15 XP_365394.1    
 MG09601.4   Magnaporthe oryzae 70-15 XP_364756.1 G5EH41
Q2KHF7
 
 MG08623.4   Magnaporthe oryzae 70-15 XP_363039.1 G4ML12  
 MGG_10662   Magnaporthe oryzae 70-15 XP_003710096.1
XP_366444.1
   
 MGG_11536   Magnaporthe oryzae 70-15 XP_003718391.1    
 MSYG_4092   Malassezia sympodialis ATCC 42132 SHO79742.1    
 ORF (fragment)   Medicago sativa AAZ32908.1 Q45NH4  
 MtrDRAFT_AC122169g13v2   Medicago truncatula ABE93020.1    
 MtrDRAFT_AC141112g18v1   Medicago truncatula ABE79280.1 G7JC76  
 BN887_03309   Melanopsichium pennsylvanicum 4 CDI52820.1    
 BN887_01304   Melanopsichium pennsylvanicum 4 CDI53611.1    
 BN887_04958   Melanopsichium pennsylvanicum 4 CDI55273.1    
 MICPUN_62504   Micromonas commoda sp. RCC299 ACO66173.1 C1EE54  
 MICPUN_77598   Micromonas commoda sp. RCC299 ACO68549.1 C1FEE0  
 MICPUN_84555   Micromonas commoda sp. RCC299 ACO69312.1 C1FGS3  
 MICPUN_84462   Micromonas commoda sp. RCC299 ACO69207.1 C1FG74  
 GNLVRS01_PISO0N13169g (Piso0_005348)   Millerozyma farinosa CBS 7064 CCE86834.1    
 GNLVRS01_PISO0M12860g (Piso0_005348)   Millerozyma farinosa CBS 7064 CCE85726.1    
 α-1,4-glucan lyase (Agll1) 4.2.2.13 Morchella costata CAB52260.1
AAE24522.1
AAR66625.1
ABA16066.1
Q9UVZ2  
 α-1,4-glucan lyase (Agll1) 4.2.2.13 Morchella vulgaris CAB52201.1
AAE24523.1
AAR66626.1
ABA16067.1
Q9UVZ1  
 α-glucosidase (AgdA) 3.2.1.20 Mortierella alliacea YN-15 BAC57563.1 Q876Z7  
 α-glucosidase 3.2.1.20 Mucor javanicus BAA11053.1 Q92442  
 soluble maltase-glucoamylase (fragment)   Mus musculus AAP55845.1 Q6XK23  
 MKIAA1161   Mus musculus BAD32395.1
AAI37641.1
AAI40957.1
CAM13275.1
Q69ZQ1  
 α-glucosidase (GAA) (lysosomal) 3.2.1.20 Mus musculus AAH10210.1
AAB06943.1
BAC34888.1
BAC40382.1
BAE23960.1
BAE27243.1
BAE30001.1
CAM15004.1
CAM15005.1
CAM15006.1
CAM15007.1
NP_032090.2
A2AFL4
P70699
P70699
 
 α-glucosidase II (?-GluII;AB;GanAB;GANAB;G2an;Kiaa0088 ) 3.2.1.20
3.2.1.84
Mus musculus AAC53182.1
AAH94437.1
AAI17889.1
AAI17890.1
AAI28070.1
BAB30982.1
BAC27099.1
BAC38370.1
BAC65483.1
BAE29025.1
NP_032086.1
A1A4T2
Q149A6
Q8BHN3
Q8BHN3
5F0E[A]
5H9O[A,C]
5HJO[A,C]
5HJR[A,C]
5IED[A]
5IEE[A]
5IEF[A]
5IEG[A]
 sucrase-isomaltase (SI;Sis)   Mus musculus 129/Sv ACH86012.1 B5THE3  
 sucrase-isomaltase (SI;Sis)   Mus musculus 129/Sv ACH86012.1 B5THE3  
 membrane-bound maltase-glucoamylase (MGAM) 3.2.1.20 Mus musculus 129/Sv ACH86011.1
AAP55844.1
B5THE2  
 membrane-bound maltase-glucoamylase (MGAM) 3.2.1.20 Mus musculus 129/Sv ACH86011.1 B5THE2  
 unnamed protein product   Mus musculus C57BL/6J BAC36303.1
BAD90228.1
CAM19521.1
CAM24145.1
Q8BVW0  
 ORF   Musca domestica ALHF AFP61348.1    
 ORF   Musca domestica ALHF AFP61383.1    
 ORF   Musca domestica ALHF AFP62244.1    
 glucosidase, alpha, neutral AB, partial (fragment)   Mustela putorius furo AER98907.1    
 glucosidase, alpha, neutral C, partial (fragment)   Mustela putorius furo AER98909.1    
 glucosidase, alpha, neutral C, partial (fragment)   Mustela putorius furo AER98910.1    
 ORF (fragment)   Mustela putorius furo AES11388.1    
 acid α-glucosidase (partial)   Mustela putorius furo AER98854.1    
 NGATSA_3032600 (short fragment)   Nannochloropsis gaditana CCMP526 AFJ69175.1    
 NCAS_0H01360 (Ncas0h01360)   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC71446.1    
 NDAI_0F01900 (Ndai0f01900)   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD25508.1    
 NCLIV_007580   Neospora caninum Liverpool CBZ50284.1    
 ORF   Nepenthes mirabilis AMN14858.1    
 NCU04203.1 (62D11.010)   Neurospora crassa OR74A CAD36981.1
XP_323543.1
Q8NIY3  
 NCU04674.1 (X4G11.130)   Neurospora crassa OR74A XP_324030.1
CAD70816.1
Q872B7  
 NCU02583.1 (B5K2.030)   Neurospora crassa OR74A CAE76419.1
XP_331782.1
Q7SHN5  
 NCU09281.1   Neurospora crassa OR74A XP_331973.1 Q7S1M6  
 NCU04885.1   Neurospora crassa OR74A XP_324242.1 Q7S081  
 α-glucosidase (fragment)   Nicotiana langsdorffii x Nicotiana sanderae ABV21576.1 B3F8X7  
 sucrase-isomaltase (SI) 3.2.1.10
3.2.1.20
3.2.1.48
Oryctolagus cuniculus AAA31459.1 P07768  
 sucrase-isomaltase (SI) 3.2.1.10
3.2.1.20
3.2.1.48
Oryctolagus cuniculus AAA31459.1 P07768  
 Os07g0421300   Oryza sativa Japonica Group BAC65988.1
BAF21397.1
BAH00276.1
BAT01190.1
   
 Os07g0420700   Oryza sativa Japonica Group BAC65981.1
BAD31751.1
BAF21394.1
BAT01184.1
   
 α-glucosidase (Ong2;Ong-2;Ong3;OngX-H3;Os06g0675700) 3.2.1.20 Oryza sativa Japonica Group BAD45910.1
BAF20261.1
BAS99103.1
Q0DA62
Q653V7
 
 α-glucosidase (Ong1;OngX-H1;Os06g0676700) 3.2.1.20 Oryza sativa Japonica Group BAD45913.1
BAD45516.1
BAF20267.1
BAS99109.1
Q653V4  
 unnamed protein product   Oryza sativa Japonica Group BAA88546.1
BAA89567.1
BAD81144.1
BAD81165.1
BAF04606.1
BAF04607.1
BAS71483.1
   
 Os03g0216600   Oryza sativa Japonica Group BAF11299.1
BAS82974.1
BAS82975.1
B9F676
Q0DTY9
 
 α-xylosidase (Ong4;OngX-H4;Os01g0130400) 3.2.1.177 Oryza sativa Japonica Group BAA99366.1
BAF03836.1
BAG95494.1
BAS70209.1
Q9LGC6  
 OSTLU_429   Ostreococcus lucimarinus CCE9901 ABO97678.1 A4S1L4  
 OSTLU_956 (fragment)   Ostreococcus lucimarinus CCE9901 ABO97736.1 A4S1X7  
 OSTLU_45442 (possible fragment)   Ostreococcus lucimarinus CCE9901 ABO95797.1 A4RW13  
 OSTLU_38421   Ostreococcus lucimarinus CCE9901 ABO96324.1 A4RXQ0  
 Ot04g02570 (probable fragment)   Ostreococcus tauri OTTH0595 CAL51655.1 Q01AZ3  
 Ot05g03140   Ostreococcus tauri OTTH0595 CAL54069.1 Q018V6  
 Ot08g02780 (fragment)   Ostreococcus tauri OTTH0595 CAL55016.1 Q013B4  
 Ot08g03750   Ostreococcus tauri OTTH0595 CAL55113.1 Q012R7  
 GANAB, partial (fragment)   Panthera tigris altaica AHJ25713.1    
 KIAA1161, partial (fragment)   Panthera tigris altaica AHJ25718.1    
 ORF   Passalora fulva 0WU AQA29335.1    
 maltase-glucoamylase (MG) (fragment)   Passer domesticus ACX53551.1 D0EYG1  
 Pc12g00950   Penicillium rubens Wisconsin 54-1255 CAP79722.1 B6GY66  
 Pc12g07810   Penicillium rubens Wisconsin 54-1255 CAP80408.1 B6GXD3  
 Pc16g05220   Penicillium rubens Wisconsin 54-1255 CAP93192.1 B6H9H5  
 Pc20g09580   Penicillium rubens Wisconsin 54-1255 CAP86287.1 B6HFB6  
 Pc21g13670   Penicillium rubens Wisconsin 54-1255 CAP96264.1 B6HNB7  
 Pc21g15870   Penicillium rubens Wisconsin 54-1255 CAP96484.1 B6HK83  
 Pc21g22730   Penicillium rubens Wisconsin 54-1255 CAP97170.1 B6HNX5  
 Pc21g23200   Penicillium rubens Wisconsin 54-1255 CAP97217.1 B6HI96  
 Pc22g09210   Penicillium rubens Wisconsin 54-1255 CAP98209.1 B6HTZ4  
 Pc22g12350   Penicillium rubens Wisconsin 54-1255 CAP98523.1 B6HRH7  
 Pc22g25710   Penicillium rubens Wisconsin 54-1255 CAP99859.1 B6HSK9  
 ORF (fragment)   Periplaneta americana AIA09350.1    
 α-1,4-glucan lyase (Agll1) (fragment)   Peziza ostracoderma CAB52202.1 Q9UVY7  
 GH31-1   Phaedon cochleariae AHH86056.1    
 ORF (fragment)   Phlebotomus perniciosus Spain ADL40394.1    
 α-glucosidase (PngcS) (fragment)   Pholiota microspora BAV90144.1    
 ORF63_ppprotl_60 (fragment)   Physcomitrella patens CAC43700.1    
 PpGLU   Physcomitrella patens subsp. patens BAB39467.1 Q9AVC3  
 WS02724_F06   Picea sitchensis ABR16166.1 B8LKI6  
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