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Glycoside Hydrolase Family 30

Activities in Familyβ-1,6-glucosidase (EC 3.2.1.-);
Glucuronoxylan endo-β-1,4-xylanase (EC 3.2.1.-);
Xylan exo-β-1,4-xylobiosidase (EC 3.2.1.-);
Glucuronoarabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.136);
[inverting] oligosaccharide reducing-end xylanase (EC 3.2.1.156);
Endo-β-1,6-galactanase (EC 3.2.1.164);
Baicalin β-glucuronidase (EC 3.2.1.167);
β-glucosidase (EC 3.2.1.21);
Galactan exo-1,6-β-galactobiohydrolase (non-reducing end) (EC 3.2.1.213);
Xylan β-1,4-xylosidase (EC 3.2.1.37);
β-D-fucosidase (EC 3.2.1.38);
β-glucosylceramidase (EC 3.2.1.45);
Endo-β-1,6-glucanase (EC 3.2.1.75);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (inferred)
NoteFollowing St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated.
External resourcesCAZypedia; Gaucher Disease; PRINTS;
Statistics GenBank accession (6933); Uniprot accession (56); PDB accession (79); 3D entries (16); cryst (1)
Summary
Download GH30 (8551) Taxonomic display Structure (16 - 1 cryst) Characterized (52)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 22 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 1681389   Gymnopilus junonius AH 44721 v1.0 (Gymjun1)       5
 1814358   Gymnopilus junonius AH 44721 v1.0 (Gymjun1)       3
 957816   Gymnopus androsaceus JB14 v1 (Gyman1)       3
 914536   Gymnopus androsaceus JB14 v1 (Gyman1)       3
 1026740   Gymnopus androsaceus JB14 v1 (Gyman1)       3
 1026304   Gymnopus androsaceus JB14 v1 (Gyman1)      
 426125   Gymnopus androsaceus JB14 v1 (Gyman1)       3
 921847   Gymnopus androsaceus JB14 v1 (Gyman1)       3
 956698   Gymnopus androsaceus JB14 v1 (Gyman1)       3
 917904   Gymnopus androsaceus JB14 v1 (Gyman1)      
 149032   Gymnopus luxurians FD-317 M1 (Gymlu1)       7
 39354   Gymnopus luxurians FD-317 M1 (Gymlu1)       3
 71310   Gymnopus luxurians FD-317 M1 (Gymlu1)       3
 195626   Gymnopus luxurians FD-317 M1 (Gymlu1)       7
 43380   Gymnopus luxurians FD-317 M1 (Gymlu1)      
 43449   Gymnopus luxurians FD-317 M1 (Gymlu1)      
 43500   Gymnopus luxurians FD-317 M1 (Gymlu1)       3
 99169   Gymnopus luxurians FD-317 M1 (Gymlu1)       3
 252454   Gymnopus luxurians FD-317 M1 (Gymlu1)      
 710351   Gyrodon lividus BX v1 (Gyrli1)       3
 HERILL_LOCUS7854   Hermetia illucens CAD7084986.1     1
 165049   Heterobasidion annosum v2.0 (Hetan2)      
 63706   Heterobasidion annosum v2.0 (Hetan2)       3
 1266587   Hexagonia nitida CIRM-BRFM 1802 (Hexnit1)       3
 407629   Hexagonia nitida CIRM-BRFM 1802 (Hexnit1)       3
 acid β-glucosidase 1 / β-glucocerebrosidase 1 (Gba1;Gba;GC;GCase;LOC82008) (lysosomal) 3.2.1.45 Homo sapiens AAA35880.1
AAA35873.1
AAA35877.1
AAC51820.1
AAC63056.1
AAH03356.1
AAQ41981.1
AAQ41982.1
AAT13636.1
AAT13637.1
AAV20581.1
AAY03281.1
AAY03324.1
ABL21565.1
ACH14936.1
ACJ92748.1
ACM85831.1
ACM97663.1
AID60277.1
AID60278.1
AID60279.1
AID60280.1
ASU47376.1
BAA02545.1
BAF84600.1
BAG58248.1
BAG60020.1
BAH12898.1
BAH13232.1
BAH13357.1
BAH13365.1
BAH13467.1
BAH13605.1
CAC41172.1
CAC41173.1
CAD12720.1
CAD12721.1
CAE85438.1
CAI95090.1
NP_000148.1
SJX47168.1		 A0A068F579
A0A068F658
A0A068F753
A0A068FB60
A0A223PQI4
B2R6A7
B4DHT6
B4DMV8
B7Z6E6
B7Z6S9
B7Z731
B7Z7G9
P04062		 1OGS[A,B]
1Y7V[A,B]
2F61[A,B]
2J25[A,B]
2NSX[A,B,C,D]
2NT0[A,B,C,D]
2NT1[A,B,C,D]
2V3D[A,B]
2V3E[A,B]
2V3F[A,B]
2VT0[A,B]
2WCG[A,B]
2WKL[A,B]
2XWD[A,B]
2XWE[A,B]
3GXD[A,B,C,D]
3GXF[A,B,C,D]
3GXI[A,B,C,D]
3GXM[A,B,C,D]
3KE0[A,B]
3KEH[A,B]
3RIK[A,B,C,D]
3RIL[A,B,C,D]
5LVX[A,B,C,D]
6MOZ[A,B]
6Q1N[A,B]
6Q1P[A,B]
6Q6K[A,B]
6Q6L[A,B]
6Q6N[A,B]
6T13[A,B,C,D]
6TJJ[AAA,BBB]
6TJK[AAA,BBB]
6TJQ[BBB]
6TN1[AAA]
6YTP[A]
6YTR[A]
6YUT[A]
6YV3[A]
6Z39[A]
6Z3I[A]
7NWV[A,B]
8AWK[A]
8AWR[A]
8AX3[A,B]
8P3E[A,B]
8P41[A,B] 		1
 GBA (pseudogene) (fragment)   Homo sapiens AID60282.1
AAH00349.2
AAH30240.1
AAH92482.1
AID60281.1
BAA02546.1
BAG52175.1
CAI95088.1
XP_034493.1		     1
 1976   Homolaphlyctis polyrhiza JEL142 v1.0 (Hompol1)      
 27243   Hortaea acidophila CBS 113389 v1.0 (Horac1)       3
 9207   Hortaea werneckii EXF-2000 M0 v1.0 (Horwer1)       3
 8009   Hortaea werneckii EXF-2000 M0 v1.0 (Horwer1)       7
 14946   Hortaea werneckii EXF-2000 M0 v1.0 (Horwer1)       3
 6503   Hortaea werneckii EXF-2000 M0 v1.0 (Horwer1)       7
 ORF   Hyalophora cecropia WWE94447.1     1
 ORF   Hyalophora cecropia WWE94500.1     1
 703317   Hyaloraphidium curvatum SAG235-1 v1.0 (Hyacur1)       5
 124301   Hyaloraphidium curvatum SAG235-1 v1.0 (Hyacur1)       5
 223515   Hydnopolyporus fimbriatus CBS384.51 v1.0 (Hydfim1)       3
 1103171   Hygrophoropsis aurantiaca ATCC 28755 v1.0 (Hygaur1)       3
 1011975   Hygrophoropsis aurantiaca ATCC 28755 v1.0 (Hygaur1)       3
 207833   Hygrophoropsis aurantiaca ATCC 28755 v1.0 (Hygaur1)       3
 944268   Hymenopellis radicata IJFM A160 v1.0 (Hymrad1)      
 1058235   Hymenopellis radicata IJFM A160 v1.0 (Hymrad1)       3
 8302   Hyphochytrium catenoides ATCC 18719 (Hypcat1)       1
 17597   Hyphochytrium catenoides ATCC 18719 (Hypcat1)       1
 459537   Hypoxylon argillaceum CBS 527.63 v1.0 (Hyparg1)       5
 505642   Hypoxylon argillaceum CBS 527.63 v1.0 (Hyparg1)       7
 489557   Hypoxylon argillaceum CBS 527.63 v1.0 (Hyparg1)       7
 392229   Hypoxylon cercidicola CBS 119009 v1.0 (Hypcer1)       3
 454759   Hypoxylon cercidicola CBS 119009 v1.0 (Hypcer1)       7
 421456   Hypoxylon cercidicola CBS 119009 v1.0 (Hypcer1)       7
 413617   Hypoxylon crocopeplum CBS 119004 v1.0 (Hypcro1)       7
 454274   Hypoxylon crocopeplum CBS 119004 v1.0 (Hypcro1)       7
 455722   Hypoxylon crocopeplum CBS 119004 v1.0 (Hypcro1)       7
 430302   Hypoxylon crocopeplum CBS 119004 v1.0 (Hypcro1)       3
 529210   Hypoxylon fragiforme CBS 206.31 v2.0 (Hypfra2)       7
 518810   Hypoxylon fragiforme CBS 206.31 v2.0 (Hypfra2)       7
 532201   Hypoxylon fragiforme CBS 206.31 v2.0 (Hypfra2)       7
 493382   Hypoxylon fuscum CBS 119018 v1.0 (Hypfus1)       7
 398259   Hypoxylon fuscum CBS 119018 v1.0 (Hypfus1)       7
 201794   Hypoxylon fuscum CBS 119018 v1.0 (Hypfus1)       7
 283043   Hypoxylon monticulosum FL0542 v1.0 (Hypmon1)       7
 290889   Hypoxylon monticulosum FL0542 v1.0 (Hypmon1)       7
 291876   Hypoxylon monticulosum FL0542 v1.0 (Hypmon1)       3
 289944   Hypoxylon monticulosum FL0542 v1.0 (Hypmon1)       7
 282320   Hypoxylon rubiginosum CBS 119005 v1.0 (Hyprub1)       3
 452565   Hypoxylon rubiginosum CBS 119005 v1.0 (Hyprub1)       7
 410400   Hypoxylon rubiginosum CBS 119005 v1.0 (Hyprub1)       7
 205673   Hypoxylon rubiginosum ER1909 v1.0 (HyprubER1909_1)       3
 281686   Hypoxylon rubiginosum ER1909 v1.0 (HyprubER1909_1)       7
 278050   Hypoxylon rubiginosum ER1909 v1.0 (HyprubER1909_1)       7
 413015   Hypoxylon sp. EC38 v3 (HypEC38_3)       7
 416498   Hypoxylon sp. EC38 v3 (HypEC38_3)       7
 468280   Hypoxylon sp. EC38 v3 (HypEC38_3)       3
 434302   Hypoxylon sp. EC38 v3 (HypEC38_3)       7
 407282   Hypoxylon sp. FL0543 v1.0 (HyFL0543_1)       7
 397739   Hypoxylon sp. FL0543 v1.0 (HyFL0543_1)       3
 278464   Hypoxylon sp. FL0543 v1.0 (HyFL0543_1)       7
 406587   Hypoxylon sp. FL0543 v1.0 (HyFL0543_1)       7
 259779   Hypoxylon sp. FL0890 v1.0 (HyFL0890_1)       7
 273560   Hypoxylon sp. FL0890 v1.0 (HyFL0890_1)       3
 277796   Hypoxylon sp. FL0890 v1.0 (HyFL0890_1)       7
 281764   Hypoxylon sp. FL0890 v1.0 (HyFL0890_1)       7
 487863   Hypoxylon sp. FL1150 v1.0 (HyFL1150_1)       7
 469047   Hypoxylon sp. FL1150 v1.0 (HyFL1150_1)       7
 571586   Hypoxylon sp. FL1284 v2.0 (HyFL1284_2)       3
 582975   Hypoxylon sp. FL1284 v2.0 (HyFL1284_2)       7
 529385   Hypoxylon sp. FL1284 v2.0 (HyFL1284_2)       7
 176971   Hypoxylon sp. FL1857 v1.0 (HyFL1857_1)       7
 181540   Hypoxylon sp. FL1857 v1.0 (HyFL1857_1)       7
 106526   Hypoxylon sp. FL1857 v1.0 (HyFL1857_1)       3
 183760   Hypoxylon sp. FL1857 v1.0 (HyFL1857_1)       7
 321330   Hypoxylon sp. NC0597 v1.0 (HyNC0597_1)       3
 664542   Hypoxylon sp. NC0597 v1.0 (HyNC0597_1)       7
 365703   Hypoxylon sp. NC0597 v1.0 (HyNC0597_1)       7
 195239   Hypoxylon sp. NC0597 v1.0 (HyNC0597_1)       7
 426493   Hypoxylon sp. NC1633 v2.0 (HyNC1633_2)       3
 632361   Hypoxylon sp. NC1633 v2.0 (HyNC1633_2)       7
 535581   Hypoxylon sp. NC1633 v2.0 (HyNC1633_2)       7
 648267   Hypoxylon sp. NC1633 v2.0 (HyNC1633_2)       7
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