Glycoside Hydrolase Family 30

Activities in Familyendo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (3.2.1.21); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-fucosidase (EC 3.2.1.38); glucosylceramidase (EC 3.2.1.45); β-1,6-glucanase (EC 3.2.1.75); glucuronoarabinoxylan endo-β-1,4-xylanase (EC 3.2.1.136); endo-β-1,6-galactanase (EC:3.2.1.164); [reducing end] β-xylosidase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (inferred)
NoteFollowing St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated.
External resourcesCAZypedia; Gaucher Disease; PRINTS;
Statistics GenBank accession (1766); Uniprot accession (263); PDB accession (46); 3D entries (11); cryst (1)
All (1632) Bacteria (1543) Eukaryota (87) unclassified (2) Structure (11 - 1 cryst) Characterized (38)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 ALNC14_004340 (Alnc14c3g399)   Albugo laibachii Nc14 CCA14291.1     1
 ORF (partial)   Amblyomma maculatum AEO33650.1     1
 ORF (fragment)   Amblyomma maculatum AEO33785.1     1
 ACCB10581   Apis cerana AEY60937.1     1
 ACCB00404.2 (fragment)   Apis cerana AEY57789.1     1
 ACCB00404.3 (fragment)   Apis cerana AEY57790.1     1
 EGX45083.1   Arthrobotrys oligospora ATCC 24927 EGX45083.1     7
 ORF   Ascaris suum ADY44488.1     1
 β-1,6-glucanase (Neg1;Afu8g07120;AFUA_8G07120) 3.2.1.75 Aspergillus fumigatus Af293 EAL85472.1
XP_747510.1
    3
 An03g00500   Aspergillus niger CBS 513.88 CAK38027.1 A2QFR7   3
 exo-β-1,4-xylanase (XylD) (acidic) 3.2.1.- Bispora sp. MEY-1 ADG62369.1 D6MYS9   7
 Unknown (protein for MGC:137522)   Bos taurus AAI12824.1 Q2KHZ8   1
 Unknown (protein for MGC:137522)   Bos taurus AAI12824.1 Q2KHZ8   1
 C33C12.3   Caenorhabditis elegans Bristol N2 CCD66449.1
AAB66056.2
ABV68956.1
CCD66450.1
NP_494207.1
O16580   1
 C33C12.8   Caenorhabditis elegans Bristol N2 AAB66060.1
AAB66060.2
CCD66456.1
NP_494208.1
O16581   1
 F11E6.1   Caenorhabditis elegans Bristol N2 CAC35807.1
CAA20283.1
CAB02924.1
CAC35813.1
CAD42642.1
CCD31056.1
NP_503118.1
NP_741501.1
G5EFK0
Q9BH43
Q9XTB0
  1
 Y4C6B.6   Caenorhabditis elegans Bristol N2 AAD14768.2
CCD71128.1
NP_500785.1
Q9UB00   1
 ORF (fragment)   Callorhinchus milii AFP09131.1     1
 endo-b-(1,6)-D-galactanase (EbG)   Colletotrichum lindemuthianum 1472 APE41966.1     5
 unknown   Dendroctonus ponderosae AEE63066.1     1
 Dbus_chr3Rg593   Drosophila busckii ALC45843.1     1
 Dbus_chr3Rg594   Drosophila busckii ALC45844.1     1
 CG31414   Drosophila melanogaster AAN13955.3
AAN13955.1
AAN13955.2
AAY55431.1
AAY55467.1
AAY55519.1
AGB96260.1
NP_732892.1
Q8IMY3   1
 CG31148   Drosophila melanogaster AAF56165.2
AAL28266.1
NP_651172.1
Q9VCJ4   1
 glucocerebrosidase 1 (Gba1)   Emiliania huxleyi AID57155.1     1
 FFUJ_12899   Fusarium fujikuroi IMI 58289 CCT73001.1     7
 FFUJ_12945   Fusarium fujikuroi IMI 58289 CCT73045.1     7
 acid β-glucosidase 1 / β-glucocerebrosidase 1 (Gba1;Gba;GC;GCase;LOC82008) (lysosomal) 3.2.1.45 Homo sapiens ASU47376.1
AAA35873.1
AAA35877.1
AAA35880.1
AAC51820.1
AAC63056.1
AAH03356.1
AAQ41981.1
AAQ41982.1
AAT13636.1
AAT13637.1
AAV20581.1
AAY03281.1
AAY03324.1
ABL21565.1
ACH14936.1
ACJ92748.1
ACM85831.1
ACM97663.1
AID60277.1
AID60278.1
AID60279.1
AID60280.1
ASU47376.1
BAA02545.1
BAF84600.1
BAG58248.1
BAG60020.1
BAH12898.1
BAH13232.1
BAH13357.1
BAH13365.1
BAH13467.1
BAH13605.1
CAC41172.1
CAC41173.1
CAD12720.1
CAD12721.1
CAE85438.1
CAI95090.1
NP_000148.1
B2R6A7
P04062
1OGS[A,B]
1Y7V[A,B]
2F61[A,B]
2J25[A,B]
2NSX[A,B,C,D]
2NT0[A,B,C,D]
2NT1[A,B,C,D]
2V3D[A,B]
2V3E[A,B]
2V3F[A,B]
2VT0[A,B]
2WCG[A,B]
2WKL[A,B]
2XWD[A,B]
2XWE[A,B]
3GXD[A,B,C,D]
3GXF[A,B,C,D]
3GXI[A,B,C,D]
3GXM[A,B,C,D]
3KE0[A,B]
3KEH[A,B]
3RIK[A,B,C,D]
3RIL[A,B,C,D]
5LVX[A,B,C,D]
1
 GBA (pseudogene)   Homo sapiens AAH92482.1
AAH00349.2
AAH30240.1
AID60281.1
AID60282.1
BAA02546.1
BAG52175.1
CAI95088.1
XP_034493.1
    1
 ORF (GbA)   Ictalurus punctatus AHH39476.1     1
 ORF (GbA)   Ictalurus punctatus AHH42685.1     1
 glucan endo-β-1,6-glucosidase (LePus30A) (Pus30A) 3.2.1.75 Lentinula edodes H600 BAK52530.1     3
 Xyl38   Leptosphaeria maculans AAO49459.1 Q873Z0   7
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX93583.1 E4ZP54   7
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX92400.1 E4ZM51   7
 glucosylceramidase isoform 1 precursor (GbA)   Macaca mulatta AFE77708.1
AFH31940.1
    1
 glucosylceramidase isoform 1 precursor (GbA)   Macaca mulatta AFJ72033.1     1
 MG02126.4   Magnaporthe oryzae 70-15 XP_365424.1 G4MNS2   3
 BN887_04456   Melanopsichium pennsylvanicum 4 CDI53006.1     3
 BN887_04929   Melanopsichium pennsylvanicum 4 CDI55227.1    
 xylanase 2 (Xyl2) (fragment)   Meloidogyne incognita ACC77826.1 C0IQA1   8
 xylanase 3 (Xyl3) (fragment)   Meloidogyne incognita ACC77827.1 C0IQA2   8
 xylanase (Mi-Xyl1;Xyl-1) 3.2.1.8 Meloidogyne incognita AAF37276.1 Q9NHE0   8
 β-glucosidase 1 / β-glucocerebrosidase (Gba;GBA;Gba1) 3.2.1.45 Mus musculus AAA37671.1
AAH06663.1
AAM66757.1
BAC38609.1
NP_032120.1
P17439   1
 ORF   Musca domestica ALHF AFP62917.1     1
 acid β-glucosidase   Mustela putorius furo AER98953.1     1
 β-1,6-glucanase (Neg1;Neg-1) 3.2.1.75 Neurospora crassa IFO6068 BAB91213.1 Q7M4T0   3
 β-1,6-glucanase (Neg1;NCU04395.1/29E8.200) 3.2.1.75 Neurospora crassa OR74A CAF06053.1
XP_323748.1
Q7M4T0   3
 endo-β-1,6-galactanase (6Gal;Nc6GAL;NCU09702.1) 3.2.1.164 Neurospora crassa OR74A XP_330352.1
EAA29705.1
Q7S2S4   5
 RNA-dependent DNA polymerase (GbA)   Oryzias latipes CDW61513.1     1
 glucocerebrosidase (Gba)   Pan troglodytes AAK18162.1 Q9BDT0   1
 glucocerebrosidase (Gba)   Pan troglodytes AAK18162.1 Q9BDT0   1
 ORF (fragment)   Papilio xuthus BAM18760.1     1
 endo-β-1,4-xylanase 5   Penicillium oxalicum GZ-2 AIO06746.1     7
 Pc22g13580   Penicillium rubens Wisconsin 54-1255 CAP98646.1 B6HTL1   3
 β-glucosidase / β-xylosidase (Bgx1) 3.2.1.21
3.2.1.37
Phytophthora infestans 88069 AAK19754.1 Q9AT27   1
 Putative Glycoside Hydrolase Family 5   Podospora anserina S mat+ CDP31966.1
CAP68494.1
B2AVS0   7
 unnamed protein product   Podospora anserina S mat+ CAP64775.1
CDP29284.1
B2ALC8   5
 Pa_5_3770   Podospora anserina S mat+ CAP64828.1
CDP29338.1
B2ALJ0   7
 DKFZp469B0323   Pongo abelii CAH90774.1 Q5R8E3   1
 DKFZp469K1734   Pongo abelii CAH91967.1 Q5R8E3   1
 DKFZp469K1734   Pongo abelii CAH91967.1 Q5R8E3   1
 xylanase (Xyl1;Rs-XYL1)   Radopholus similis ABZ78968.1 B3TJG3   8
 Unknown protein for MGC:188451   Rattus norvegicus AAI66732.1 B2RYC9   1
 PIIN_00485   Serendipita indica DSM 11827 CCA77838.1     3
 sr15243   Sporisorium reilianum SRZ2 CBQ69174.1     3
 sr13131   Sporisorium reilianum SRZ2 CBQ72423.1     3
 SPSC_00891   Sporisorium scitamineum SscI8 CDU22261.1     3
 SPSC_05923   Sporisorium scitamineum SscI8 CDU25752.1     3
 SRAE_2000264000   Strongyloides ratti ED321 Heterogonic CEF67979.1     1
 AWJ20_568   Sugiyamaella lignohabitans CBS 10342 ANB12318.1     7
 GBA   Sus scrofa CAE06498.1 Q70KH2   1
 GBA   Sus scrofa CAE06498.1 Q70KH2   1
 xylanase (XynC;XYNC)   Talaromyces purpureogenus ATCC MYA-38 AKH40280.1     7
 MYCTH_38558   Thermothelomyces thermophila ATCC 42464 AEO55025.1     7
 MYCTH_2301720   Thermothelomyces thermophila ATCC 42464 AEO56615.1     5
 MYCTH_101800 (Gxhl)   Thermothelomyces thermophila ATCC 42464 AEO57693.1     7
 THITE_2117640   Thielavia terrestris NRRL 8126 AEO68216.1     3
 THITE_2123443   Thielavia terrestris NRRL 8126 AEO71253.1     7
 THITE_30409   Thielavia terrestris NRRL 8126 AEO71227.1     7
 GH30   Tisochrysis lutea AHW52384.1     1
 β-1,6-glucanase (Bgn16.3;P2) 3.2.1.75 Trichoderma harzianum CAC80492.1
ACM42429.1
Q8J0I9   3
 glucuronoxylan hydrolase (xylanase cleaving 4-Me-GlcA or GlcA-substituted xylan; TRIREDRAFT_69276) 3.2.1.- Trichoderma reesei QM6a EGR45006.1     7
 exo-xylanase IV (Xyn4;XYN IV) 3.2.1.- Trichoderma reesei Rut C30 AAP64786.1
AAV25955.1
  cryst 7
 endo-β-1,6-galactanase (6GAL;Tv6GAL;Tv1,6Gal5A) (1,6Gal5A) 3.2.1.164 Trichoderma viride BAC84995.1 Q76FP5   5
 UBRO_06809   Ustilago bromivora UB2112 SAM84178.1     3
 UBRO_03204   Ustilago bromivora UB2112 SAM81688.1     3
 MGC84284 (fragment)   Xenopus laevis AAH81165.1 Q66IW2   1
 glucocerebrosidase (Zfgba1)   Zygaena filipendulae SGZ49395.1     1
 ZT1A5_G4476   Zymoseptoria tritici ST99CH_1A5 SMY23036.1     3
 ZT3D7_G4491   Zymoseptoria tritici ST99CH_3D7 SMQ49340.1     3
Top


Last update: 2017-11-06 © Copyright 1998-2017
AFMB - CNRS - Université d'Aix-Marseille