Glycoside Hydrolase Family 20

Activities in Familyβ-1,6-N-acetylglucosaminidase (EC 3.2.1.-);
β-N-acetyl-6-sulfo-glucosaminidase (EC 3.2.1.-);
Lacto-N-biosidase (EC 3.2.1.140);
β-N-acetylhexosaminidase (EC 3.2.1.52);
Mannosyl-glycoprotein endo-β-N-acetylglucosaminidase (EC 3.2.1.96);
Mechanism Retaining e
ClanGH-K
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu
External resourcesCAZypedia; HOMSTRAD; PRINTS; Tay-Sachs Disease;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (19992); Uniprot accession (182); PDB accession (113); 3D entries (32); cryst (0)
| 1 | ... | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | ... | 39 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 DMAD_00497   Drosophila madeirensis RF1 BFG00526.1    
 DMAD_06087   Drosophila madeirensis RF1 BFF97726.1    
 DMAD_08817   Drosophila madeirensis RF1 BFF90263.1    
 DMAD_03067   Drosophila madeirensis RF1 BFG03970.1    
 DMAD_02091   Drosophila madeirensis RF1 BFG02625.1    
 CG7985   Drosophila melanogaster AAF55509.2
AGB96079.1
   
 β-N-acetylhexosaminidase 2 / b(2)-subunit (Hexo2;Hex2;CG1787) 3.2.1.52 Drosophila melanogaster AAF46406.1
AAM48390.1
NP_525081.1
Q9W3C4  
 β-N-acetylhexosaminidase 1 / b(1)-subunit (Hexo1;Hex1;CG1318) 3.2.1.52 Drosophila melanogaster AAF47881.1
AAG22248.1
AAG22248.2
AAL28566.1
AAM49995.1
AAN11596.1
AAN11597.1
AAN11597.2
ACU43551.1
NP_523924.1
NP_728974.1
NP_728975.1
NP_728976.1
Q0E8H9
Q8IRB6
Q8MSS9
Q95S03
Q9VZE3
 
 processing β-N-acetylglucosaminidase / α-subunit (Fdl;DmFDL;CG8824;Dmel_CG8824) 3.2.1.52 Drosophila melanogaster AAM29423.1
AAF58500.2
AAL55992.1
AAM68691.1
AAM68691.2
AAM68692.1
AAM68693.1
ABY20426.1
AFC17499.1
AHN56148.1
AHN56149.1
NP_610790.1
NP_725178.2
NP_725179.1
NP_725180.1
QCD26198.1
A0A0B4LF89
A0A0B4LG91
A0A4P7VJW3
A9UN21
H5V8F4
Q8WSF3
 
 GA14705 (fragment)   Drosophila miranda 0101.3 ADJ12629.1    
 GA14705 (fragment)   Drosophila miranda SP295 ADJ12636.1    
 GI16594 (short fragment)   Drosophila mojavensis ANZA402.17 AEE61329.1    
 GA14705 (fragment)   Drosophila pseudoobscura MV1 ADJ12645.1    
 453083   Durotheca rogersii YMJ 92031201 v1.0 (Durrog2)      
 302821   Durotheca rogersii YMJ 92031201 v1.0 (Durrog2)      
 758244   Earliella scabrosa CIRM-BRFM 1817 v1.0 (Earsca1)      
 758290   Earliella scabrosa CIRM-BRFM 1817 v1.0 (Earsca1)      
 727779   Earliella scabrosa CIRM-BRFM 1817 v1.0 (Earsca1)      
 855853   Earliella scabrosa CIRM-BRFM 1817 v1.0 (Earsca1)      
 618746   Earliella scabrosa CIRM-BRFM 1817 v1.0 (Earsca1)      
 795561   Earliella scabrosa CIRM-BRFM 1817 v1.0 (Earsca1)      
 6030   Elsinoe ampelina CECT 20119 v1.0 (Elsamp1)      
 681330   Acremonium sp. TS7 v1.0 (AcreTS7_1)      
 9683   Acremonium sp. TS7 v1.0 (AcreTS7_1)      
 446686   Emiliania huxleyi (Emihu1)      
 440875   Emiliania huxleyi (Emihu1)      
 237396   Emiliania huxleyi (Emihu1)      
 77540   Emiliania huxleyi (Emihu1)      
 71027   Emiliania huxleyi (Emihu1)      
 238482   Emiliania huxleyi (Emihu1)      
 PRK78_003525 (Nag1_1)   Emydomyces testavorans 16-2883 WEW58058.1    
 PRK78_003816 (Hex1)   Emydomyces testavorans 16-2883 WEW58348.1    
 5116   Endocarpon pusillum Z07020 (EndpusZ1)      
 90556   Endogone sp FLAS 59071 (Endsp1)      
 90009   Endogone sp FLAS 59071 (Endsp1)      
 88353   Endogone sp FLAS 59071 (Endsp1)      
 89066   Endogone sp FLAS 59071 (Endsp1)      
 β-N-acetylglucosaminidase B / β-subunit / hexosaminidase 1 (HexB;Hex1)   Entamoeba histolytica HM-1:IMSS CAD10500.3    
 β-N-acetylglucosaminidase A / α-subunit (HexA;Hex-A;Bex-1;EHI_148130) 3.2.1.52 Entamoeba histolytica HM-1:IMSS CAE46968.1
AAA80165.1
CAG23943.1
EAL52144.2
C4LSY3
P49009
 
 441598   Entophlyctis helioformis JEL805 v1.0 (Enthel1)      
 402521   Entophlyctis helioformis JEL805 v1.0 (Enthel1)      
 C2857_000377 (Hex1)   Epichloe festucae Fl1 QPH09543.1    
 46686   Epithele typhae CBS 203.58 v1.0 (Epityp1)      
 92773   Epithele typhae CBS 203.58 v1.0 (Epityp1)      
 96689   Epithele typhae CBS 203.58 v1.0 (Epityp1)      
 89897   Epithele typhae CBS 203.58 v1.0 (Epityp1)      
 46673   Epithele typhae CBS 203.58 v1.0 (Epityp1)      
 421   Erysiphe necator c (Erynec1)      
 M5689_001803   Euphorbia peplus WCJ19515.1    
 M5689_001357   Euphorbia peplus WCJ19046.1    
 M5689_019959   Euphorbia peplus WCJ38929.1    
 411763   Eurotium rubrum v1.0 (Eurhe1)      
 9456   Eutypa lata UCREL1 (Eutla1)      
 10779   Eutypa lata UCREL1 (Eutla1)      
 5355   Eutypa lata UCREL1 (Eutla1)      
 674941   Exidia glandulosa v1 (Exigl1)      
 601286   Exidia glandulosa v1 (Exigl1)      
 607474   Exidia glandulosa v1 (Exigl1)      
 666216   Exidia glandulosa v1 (Exigl1)      
 829985   Exidia glandulosa v1 (Exigl1)      
 CBS101457_003442   Exobasidium rhododendri CBS101457 UZJ54122.1    
 CBS101457_005483 (fragment)   Exobasidium rhododendri CBS101457 UZJ56163.1    
 5701   Exophiala aquamarina CBS 119918 (Exoaq1)      
 4177   Exophiala aquamarina CBS 119918 (Exoaq1)      
 6502   Exophiala dermatitidis UT8656 (Exode1)      
 6246   Exophiala dermatitidis UT8656 (Exode1)      
 112294   Exophiala mesophila CBS40295 (Exome1)      
 107136   Exophiala mesophila CBS40295 (Exome1)      
 138350   Exophiala oligosperma CBS72588 (Exool1)      
 138885   Exophiala oligosperma CBS72588 (Exool1)      
 119528   Exophiala sideris CBS121828 (Exosi1)      
 120191   Exophiala sideris CBS121828 (Exosi1)      
 119527   Exophiala sideris CBS121828 (Exosi1)      
 6539   Exophiala spinifera CBS89968 (Exosp1)      
 6031   Exophiala spinifera CBS89968 (Exosp1)      
 687064   Eurotiomycetes sp. JF 03-3F Goopy v1.0 (EurotioJF033F_1)      
 5286   Eurotiomycetes sp. JF 03-3F Goopy v1.0 (EurotioJF033F_1)      
 441659   Eurotiomycetes sp. JF 03-4F Slimey v1.0 (EurotioJF034F_1)      
 113277   Eurotiomycetes sp. JF 03-4F Slimey v1.0 (EurotioJF034F_1)      
 144344   Exophiala xenobiotica CBS118157 (Exoxe1)      
 144135   Exophiala xenobiotica CBS118157 (Exoxe1)      
 N-acetyl β-glucosaminidase (β-chain)   Felis catus AAB30707.2
AAB67612.1
AEP60131.1
   
 β-N-acetylhexosaminidase alpha subunit (HexA)   Felis catus AEP60130.1    
 504767   Fennellomyces sp. T-0311 v1.0 (Fenlin1)      
 656844   Fennellomyces sp. T-0311 v1.0 (Fenlin1)      
 523787   Fennellomyces sp. T-0311 v1.0 (Fenlin1)      
 6878   Fibroporia radiculosa TFFH 294 (Fibra1)      
 7708   Fibroporia radiculosa TFFH 294 (Fibra1)      
 744208   Fibulorhizoctonia sp. CBS 109695 (Fibsp1)      
 961358   Fibulorhizoctonia sp. CBS 109695 (Fibsp1)      
 797178   Fibulorhizoctonia sp. CBS 109695 (Fibsp1)      
 316032   Filobasidium floriforme CBS 6241 v1.0 (Filflo1)      
 608318   Fimicolochytrium jonesii JEL569 v1.0 (Fimjon1)      
 268441   Fimicolochytrium jonesii JEL569 v1.0 (Fimjon1)      
 55935   Fistulina hepatica (Fishe1)      
 35305   Fistulina hepatica (Fishe1)      
 69844   Fistulina hepatica (Fishe1)      
 1241575   Fomes fomentarius CIRM-BRFM 1821 (Fomfom1)      
 1424728   Fomes fomentarius CIRM-BRFM 1821 (Fomfom1)      
 1317821   Fomes fomentarius CIRM-BRFM 1821 (Fomfom1)      
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