Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (55939); Uniprot accession (7858); PDB accession (467); 3D entries (111); cryst (2)
All (51170) Archaea (370) Bacteria (47636) Eukaryota (3034) unclassified (130) Structure (111 - 2 cryst) Characterized (812)
| 1 | ... | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | ... | 477 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 ACWT_5200   Actinoplanes sp. SE50 ATO84615.1     16
 ACWT_5199   Actinoplanes sp. SE50 ATO84614.1     3
 ACWT_5089   Actinoplanes sp. SE50 ATO84504.1    
 ACWT_6708   Actinoplanes sp. SE50 ATO86123.1     30
 ACWT_3556   Actinoplanes sp. SE50 ATO82971.1     2
 ACWT_2701   Actinoplanes sp. SE50 ATO82116.1     11
 ACPL_6621 (TreZ)   Actinoplanes sp. SE50/110 AEV87503.1
SLM03320.1
    10
 ACPL_6622 (TreY)   Actinoplanes sp. SE50/110 AEV87504.1
SLM03321.1
    26
 ACPL_1259 (AglC)   Actinoplanes sp. SE50/110 AEV82156.1
SLL97961.1
    30
 ACPL_2033   Actinoplanes sp. SE50/110 AEV82930.1
SLL98733.1
   
 ACPL_2547   Actinoplanes sp. SE50/110 AEV83442.1
SLL99243.1
    30
 ACPL_3988 (AmyA)   Actinoplanes sp. SE50/110 AEV84883.1
SLM00681.1
   
 ACPL_4500   Actinoplanes sp. SE50/110 AEV85391.1
SLM01194.1
   
 ACPL_4688 (GlgX)   Actinoplanes sp. SE50/110 AEV85579.1
SLM01382.1
    11
 ACPL_5329 (GlgE)   Actinoplanes sp. SE50/110 AEV86216.1
SLM02024.1
    3
 ACPL_5330 (TreS)   Actinoplanes sp. SE50/110 AEV86217.1
SLM02025.1
    16
 ACPL_5332 (GlgB)   Actinoplanes sp. SE50/110 AEV86219.1
SLM02027.1
    9
 ACPL_6399 (PulA)   Actinoplanes sp. SE50/110 AEV87281.1
SLM03094.1
   
 ACPL_6399 (PulA)   Actinoplanes sp. SE50/110 AEV87281.1
SLM03094.1
    13
 ACPL_6623 (GlgX)   Actinoplanes sp. SE50/110 AEV87505.1
SLM03322.1
    11
 ACPL_6822 (MalL)   Actinoplanes sp. SE50/110 AEV87704.1
SLM03521.1
    31
 ACPL_6838 (AglA)   Actinoplanes sp. SE50/110 AEV87720.1
SLM03537.1
    30
 ACPL_7518 (TreS)   Actinoplanes sp. SE50/110 AEV88398.1
SLM04221.1
    16
 ACPL_2845   Actinoplanes sp. SE50/110 AEV83740.1
SLL99523.1
    11
 ACPL_5219 (GlgB)   Actinoplanes sp. SE50/110 AEV86106.1
SLM01914.1
   
 ACPL_5621   Actinoplanes sp. SE50/110 AEV86508.1
SLM02315.1
    32
 α-amylase (AcbZ; ACPL_3663)   Actinoplanes sp. SE50/110 CAJ81018.1
AEV84558.1
SLM00358.1
Q27GS8  
 acarbose resistent α-amylase (AcbE;ACPL_3683) 3.2.1.1 Actinoplanes sp. SE50/110 AEV84578.1
CAC02970.1
CAJ81030.1
SLM00378.1
Q27GR6
Q9K5L6
 
 acarviosyltransferase (AcbD; ACPL_3684) 2.4.1.- Actinoplanes sp. SE50/110 CAC02971.1
AAE37556.1
AEV84579.1
CAJ81031.1
SLM00379.1
Q9K5L5   2
 PepI (fragment)   Actinoplanes sp. SN223/29 ABV26718.1 A8QWZ9  
 trehalose synthase (TreS) 5.4.99.16 Actinoplanes sp. SN223/29 ABV26719.1 A8QX00   16
 TreX   Actinoplanes sp. SN223/29 ABV26724.1 A8QX06   11
 malto-oligosyltrehalose synthase (TreY) 5.4.99.15 Actinoplanes sp. SN223/29 ABV26725.1 A8QX07   26
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Actinoplanes sp. SN223/29 ABV26726.1 A8QX08   10
 SAMN04489717_4654   Actinopolymorpha singaporensis DSM 22024 SDT00113.1     26
 SAMN04489717_5466   Actinopolymorpha singaporensis DSM 22024 SDT20232.1     9
 SAMN04489717_3520   Actinopolymorpha singaporensis DSM 22024 SDS68593.1     30
 SAMN04489717_4017   Actinopolymorpha singaporensis DSM 22024 SDS82798.1     11
 SAMN04489717_1709   Actinopolymorpha singaporensis DSM 22024 SDS12780.1     30
 SAMN04489717_3155   Actinopolymorpha singaporensis DSM 22024 SDS58206.1     30
 SAMN04489717_5464   Actinopolymorpha singaporensis DSM 22024 SDT20198.1     16
 SAMN04489717_5461   Actinopolymorpha singaporensis DSM 22024 SDT20116.1    
 SAMN04489717_4653   Actinopolymorpha singaporensis DSM 22024 SDT00094.1     10
 SAMN04489717_5463   Actinopolymorpha singaporensis DSM 22024 SDT20176.1     3
 SAMN04489717_5377   Actinopolymorpha singaporensis DSM 22024 SDT18264.1     11
 CDG81_11840   Actinopolyspora erythraea YIM 90600 ASU78856.1     32
 CDG81_12455 (fragment)   Actinopolyspora erythraea YIM 90600 ASU81072.1     30
 Amir_1134   Actinosynnema mirum DSM 43827 ACU35089.1 C6WQ33   30
 Amir_3009   Actinosynnema mirum DSM 43827 ACU36929.1 C6WRT7   31
 Amir_3708   Actinosynnema mirum DSM 43827 ACU37591.1 C6WC24   16
 Amir_5113   Actinosynnema mirum DSM 43827 ACU38935.1 C6W888   26
 Amir_5114   Actinosynnema mirum DSM 43827 ACU38936.1 C6W889   11
 Amir_6072   Actinosynnema mirum DSM 43827 ACU39879.1 C6WGB5   3
 Amir_6073   Actinosynnema mirum DSM 43827 ACU39880.1 C6WGB6   16
 Amir_6075   Actinosynnema mirum DSM 43827 ACU39882.1 C6WGB8   9
 Amir_1130   Actinosynnema mirum DSM 43827 ACU35085.1 C6WQ29   32
 Amir_1170   Actinosynnema mirum DSM 43827 ACU35124.1 C6WQ68  
 Amir_1170   Actinosynnema mirum DSM 43827 ACU35124.1 C6WQ68   13
 Amir_5112   Actinosynnema mirum DSM 43827 ACU38934.1 C6W887   10
 Amir_6067   Actinosynnema mirum DSM 43827 ACU39874.1 C6WGB0   11
 CNX65_29865 (GlgX)   Actinosynnema pretiosum X47 ATE56977.1     11
 CNX65_25410 (TreZ)   Actinosynnema pretiosum X47 ATE56199.1     10
 CNX65_25415 (TreY)   Actinosynnema pretiosum X47 ATE56200.1     26
 CNX65_29895 (TreS)   Actinosynnema pretiosum X47 ATE56982.1     16
 CNX65_18575   Actinosynnema pretiosum X47 ATE55041.1     16
 CNX65_15165   Actinosynnema pretiosum X47 ATE54463.1     31
 CNX65_29890   Actinosynnema pretiosum X47 ATE56981.1     3
 CNX65_05840   Actinosynnema pretiosum X47 ATE52860.1    
 CNX65_05840   Actinosynnema pretiosum X47 ATE52860.1     13
 CNX65_25420 (GlgX)   Actinosynnema pretiosum X47 ATE56201.1     11
 CNX65_05655   Actinosynnema pretiosum X47 ATE52828.1     30
 CNX65_05635   Actinosynnema pretiosum X47 ATE58006.1     32
 FB03_01500   Actinotignum schaalii CCUG 27420 AIE82167.1     26
 FB03_05870   Actinotignum schaalii CCUG 27420 AIE82860.1     30
 FB03_07780   Actinotignum schaalii CCUG 27420 AIE83159.1    
 FB03_08535   Actinotignum schaalii CCUG 27420 AIE83267.1     30
 FB03_08560   Actinotignum schaalii CCUG 27420 AIE83272.1     9
 FB03_08570   Actinotignum schaalii CCUG 27420 AIE83273.1     16
 FB03_08575   Actinotignum schaalii CCUG 27420 AIE83274.1     3
 FB03_08590   Actinotignum schaalii CCUG 27420 AIE83277.1     11
 FB03_01495   Actinotignum schaalii CCUG 27420 AIE82166.1     10
 FB03_01505   Actinotignum schaalii CCUG 27420 AIE82168.1     11
 ADH66_17495   Acutalibacter muris KB18 ASB42289.1    
 ADH66_07440   Acutalibacter muris KB18 ASB40508.1     9
 ADH66_14400   Acutalibacter muris KB18 ASB42775.1     39
 ADH66_16090   Acutalibacter muris KB18 ASB42041.1     18
 ADH66_13280   Acutalibacter muris KB18 ASB41540.1     11
 AP3564_13830   Aeribacillus pallidus KCTC3564 ASS91157.1    
 AP3564_13810   Aeribacillus pallidus KCTC3564 ASS91153.1     20
 AP3564_13685   Aeribacillus pallidus KCTC3564 ASS91133.1     31
 AP3564_10590   Aeribacillus pallidus KCTC3564 ASS90608.1     29
 AP3564_13720   Aeribacillus pallidus KCTC3564 ASS91139.1     31
 AP3564_09945   Aeribacillus pallidus KCTC3564 ASS90496.1    
 AWM71_03640   Aerococcus christensenii CCUG28831 AMB92451.1    
 AWM71_05325   Aerococcus christensenii CCUG28831 AMB92732.1    
 AWM71_05295   Aerococcus christensenii CCUG28831 AMB92727.1     20
 AWM72_04580   Aerococcus sanguinicola CCUG43001 AMB94082.1    
 AWM72_03810   Aerococcus sanguinicola CCUG43001 AMB93946.1     29
 AWM72_03790   Aerococcus sanguinicola CCUG43001 AMB93942.1     5
 AWM72_00385   Aerococcus sanguinicola CCUG43001 AMB93334.1     9
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