Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (54252); Uniprot accession (7858); PDB accession (465); 3D entries (110); cryst (2)
All (49476) Archaea (367) Bacteria (45982) Eukaryota (2997) unclassified (130) Structure (110 - 2 cryst) Characterized (812)
| 1 | ... | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | ... | 460 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Actinoplanes sp. SN223/29 ABV26726.1 A8QX08   10
 SAMN04489717_4654   Actinopolymorpha singaporensis DSM 22024 SDT00113.1     26
 SAMN04489717_5466   Actinopolymorpha singaporensis DSM 22024 SDT20232.1     9
 SAMN04489717_3520   Actinopolymorpha singaporensis DSM 22024 SDS68593.1     30
 SAMN04489717_4017   Actinopolymorpha singaporensis DSM 22024 SDS82798.1     11
 SAMN04489717_1709   Actinopolymorpha singaporensis DSM 22024 SDS12780.1     30
 SAMN04489717_3155   Actinopolymorpha singaporensis DSM 22024 SDS58206.1     30
 SAMN04489717_5464   Actinopolymorpha singaporensis DSM 22024 SDT20198.1     16
 SAMN04489717_5461   Actinopolymorpha singaporensis DSM 22024 SDT20116.1    
 SAMN04489717_4653   Actinopolymorpha singaporensis DSM 22024 SDT00094.1     10
 SAMN04489717_5463   Actinopolymorpha singaporensis DSM 22024 SDT20176.1     3
 SAMN04489717_5377   Actinopolymorpha singaporensis DSM 22024 SDT18264.1     11
 CDG81_11840   Actinopolyspora erythraea YIM 90600 ASU78856.1     32
 CDG81_12455 (fragment)   Actinopolyspora erythraea YIM 90600 ASU81072.1     30
 Amir_1134   Actinosynnema mirum DSM 43827 ACU35089.1 C6WQ33   30
 Amir_3009   Actinosynnema mirum DSM 43827 ACU36929.1 C6WRT7   31
 Amir_3708   Actinosynnema mirum DSM 43827 ACU37591.1 C6WC24   16
 Amir_5113   Actinosynnema mirum DSM 43827 ACU38935.1 C6W888   26
 Amir_5114   Actinosynnema mirum DSM 43827 ACU38936.1 C6W889   11
 Amir_6072   Actinosynnema mirum DSM 43827 ACU39879.1 C6WGB5   3
 Amir_6073   Actinosynnema mirum DSM 43827 ACU39880.1 C6WGB6   16
 Amir_6075   Actinosynnema mirum DSM 43827 ACU39882.1 C6WGB8   9
 Amir_1130   Actinosynnema mirum DSM 43827 ACU35085.1 C6WQ29   32
 Amir_1170   Actinosynnema mirum DSM 43827 ACU35124.1 C6WQ68  
 Amir_1170   Actinosynnema mirum DSM 43827 ACU35124.1 C6WQ68   13
 Amir_5112   Actinosynnema mirum DSM 43827 ACU38934.1 C6W887   10
 Amir_6067   Actinosynnema mirum DSM 43827 ACU39874.1 C6WGB0   11
 CNX65_29865 (GlgX)   Actinosynnema pretiosum X47 ATE56977.1     11
 CNX65_25410 (TreZ)   Actinosynnema pretiosum X47 ATE56199.1     10
 CNX65_25415 (TreY)   Actinosynnema pretiosum X47 ATE56200.1     26
 CNX65_29895 (TreS)   Actinosynnema pretiosum X47 ATE56982.1     16
 CNX65_18575   Actinosynnema pretiosum X47 ATE55041.1     16
 CNX65_15165   Actinosynnema pretiosum X47 ATE54463.1     31
 CNX65_29890   Actinosynnema pretiosum X47 ATE56981.1     3
 CNX65_05840   Actinosynnema pretiosum X47 ATE52860.1    
 CNX65_05840   Actinosynnema pretiosum X47 ATE52860.1     13
 CNX65_25420 (GlgX)   Actinosynnema pretiosum X47 ATE56201.1     11
 CNX65_05655   Actinosynnema pretiosum X47 ATE52828.1     30
 CNX65_05635   Actinosynnema pretiosum X47 ATE58006.1     32
 FB03_01500   Actinotignum schaalii CCUG 27420 AIE82167.1     26
 FB03_05870   Actinotignum schaalii CCUG 27420 AIE82860.1     30
 FB03_07780   Actinotignum schaalii CCUG 27420 AIE83159.1    
 FB03_08535   Actinotignum schaalii CCUG 27420 AIE83267.1     30
 FB03_08560   Actinotignum schaalii CCUG 27420 AIE83272.1     9
 FB03_08570   Actinotignum schaalii CCUG 27420 AIE83273.1     16
 FB03_08575   Actinotignum schaalii CCUG 27420 AIE83274.1     3
 FB03_08590   Actinotignum schaalii CCUG 27420 AIE83277.1     11
 FB03_01495   Actinotignum schaalii CCUG 27420 AIE82166.1     10
 FB03_01505   Actinotignum schaalii CCUG 27420 AIE82168.1     11
 ADH66_17495   Acutalibacter muris KB18 ASB42289.1    
 ADH66_07440   Acutalibacter muris KB18 ASB40508.1     9
 ADH66_14400   Acutalibacter muris KB18 ASB42775.1     39
 ADH66_16090   Acutalibacter muris KB18 ASB42041.1     18
 ADH66_13280   Acutalibacter muris KB18 ASB41540.1     11
 AP3564_13830   Aeribacillus pallidus KCTC3564 ASS91157.1    
 AP3564_13810   Aeribacillus pallidus KCTC3564 ASS91153.1     20
 AP3564_13685   Aeribacillus pallidus KCTC3564 ASS91133.1     31
 AP3564_10590   Aeribacillus pallidus KCTC3564 ASS90608.1     29
 AP3564_13720   Aeribacillus pallidus KCTC3564 ASS91139.1     31
 AP3564_09945   Aeribacillus pallidus KCTC3564 ASS90496.1    
 AWM71_03640   Aerococcus christensenii CCUG28831 AMB92451.1    
 AWM71_05325   Aerococcus christensenii CCUG28831 AMB92732.1    
 AWM71_05295   Aerococcus christensenii CCUG28831 AMB92727.1     20
 AWM72_04580   Aerococcus sanguinicola CCUG43001 AMB94082.1    
 AWM72_03810   Aerococcus sanguinicola CCUG43001 AMB93946.1     29
 AWM72_03790   Aerococcus sanguinicola CCUG43001 AMB93942.1     5
 AWM72_00385   Aerococcus sanguinicola CCUG43001 AMB93334.1     9
 AWM72_06580   Aerococcus sanguinicola CCUG43001 AMB94449.1     14
 HMPREF9243_0592 (PulA)   Aerococcus urinae ACS-120-V-Col10a AEA00956.1     14
 HMPREF9243_0376   Aerococcus urinae ACS-120-V-Col10a AEA01295.1    
 HMPREF9243_0995   Aerococcus urinae ACS-120-V-Col10a AEA00598.1     5
 AWM73_07620   Aerococcus urinae CCUG36881 AMB96373.1    
 AWM73_03965   Aerococcus urinae CCUG36881 AMB95712.1     9
 AWM73_04790   Aerococcus urinae CCUG36881 AMB95866.1     5
 AWM73_06605   Aerococcus urinae CCUG36881 AMB96186.1     14
 AWM74_03910   Aerococcus urinaeequi CCUG28094 AMB97437.1     20
 AWM74_03730   Aerococcus urinaeequi CCUG28094 AMB97407.1     29
 AWM74_00235   Aerococcus urinaeequi CCUG28094 AMB98395.1     9
 AWM74_04100   Aerococcus urinaeequi CCUG28094 AMB97472.1    
 AWM74_04915   Aerococcus urinaeequi CCUG28094 AMB97609.1     5
 AWM74_06505   Aerococcus urinaeequi CCUG28094 AMB97913.1     14
 AWM74_09100   Aerococcus urinaeequi CCUG28094 AMB98360.1     18
 APT62_00785   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ87073.1     20
 APT62_04490   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ88711.1     9
 APT62_07585   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ88305.1     14
 APT62_04890   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ87836.1     18
 APT62_00940   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ87098.1     29
 APT62_04880   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ87834.1     31
 APT62_00590   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ87037.1    
 APT62_09220   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ88615.1     5
 AWM75_05975   Aerococcus urinaehominis CCUG42038B AMB99572.1     14
 AWM75_04960   Aerococcus urinaehominis CCUG42038B AMB99380.1    
 AWM75_04430   Aerococcus urinaehominis CCUG42038B AMB99293.1     5
 AWM75_08230   Aerococcus urinaehominis CCUG42038B AMB99958.1     29
 AWM76_02695   Aerococcus viridans CCUG4311 AMC00559.1     14
 AWM76_09635   Aerococcus viridans CCUG4311 AMC01788.1     29
 AWM76_09805   Aerococcus viridans CCUG4311 AMC01817.1     20
 AWM76_05355   Aerococcus viridans CCUG4311 AMC01013.1     31
 AWM76_10010   Aerococcus viridans CCUG4311 AMC01852.1    
 AWM76_05815   Aerococcus viridans CCUG4311 AMC01944.1     9
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