Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (65173); Uniprot accession (7872); PDB accession (486); 3D entries (114); cryst (2)
All (60304) Archaea (391) Bacteria (56446) Eukaryota (3337) unclassified (130) Structure (114 - 2 cryst) Characterized (815)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 565 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 APP7_0352   Actinobacillus pleuropneumoniae serovar 7 str. AP76 ACE61004.1 B3H0J2   11
 MIDG2331_00362 (GlgB)   Actinobacillus pleuropneumoniae serovar 8 CUU51667.1     9
 MIDG2331_00363 (GlgX)   Actinobacillus pleuropneumoniae serovar 8 CUU51668.1     11
 DDU33_09930 (TreC)   Actinobacillus porcitonsillarum 9953L55 AWI51781.1     29
 DDU33_08315   Actinobacillus porcitonsillarum 9953L55 AWI51480.1     9
 DDU33_08320 (GlgX)   Actinobacillus porcitonsillarum 9953L55 AWI51481.1     11
 DDU33_04220   Actinobacillus porcitonsillarum 9953L55 AWI50739.1     19
 Asuc_1353   Actinobacillus succinogenes 130Z ABR74713.1 A6VP16   11
 Asuc_1352   Actinobacillus succinogenes 130Z ABR74712.1 A6VP15   9
 Asuc_0321   Actinobacillus succinogenes 130Z ABR73699.1 A6VL52  
 Asuc_0315   Actinobacillus succinogenes 130Z ABR73693.1 A6VL46   19
 ASU1_06960   Actinobacillus suis ATCC 33415 AIJ31653.1     29
 ASU1_02225   Actinobacillus suis ATCC 33415 AIJ30721.1     11
 ASU1_02220   Actinobacillus suis ATCC 33415 AIJ30720.1     9
 ASU2_06885   Actinobacillus suis H91-0380 AFU19515.1     29
 ASU2_02220   Actinobacillus suis H91-0380 AFU18586.1     11
 ASU2_02215   Actinobacillus suis H91-0380 AFU18585.1     9
 SAMEA4504061_01453 (TreA)   Actinobacillus suis NCTC12996 SNV35282.1     29
 SAMEA4504061_00456 (GlgB)   Actinobacillus suis NCTC12996 SNV27985.1     9
 SAMEA4504061_00457 (GlgX)   Actinobacillus suis NCTC12996 SNV27992.1     11
 IMCC26256_1192   Actinobacteria bacterium IMCC26256 AKL72400.1     23
 BH719_01310   Actinomyces hongkongensis HKU8 AOS46687.1     31
 BH719_02795   Actinomyces hongkongensis HKU8 AOS46924.1     13
 BH719_01345   Actinomyces hongkongensis HKU8 AOS46689.1     11
 BH719_07970   Actinomyces hongkongensis HKU8 AOS47784.1     31
 BH719_02715   Actinomyces hongkongensis HKU8 AOS46910.1    
 BH719_03025   Actinomyces hongkongensis HKU8 AOS46959.1     29
 ADJ76_04115   Actinomyces meyeri W712 AKU65048.1     3
 ADJ76_04100   Actinomyces meyeri W712 AKU65045.1     11
 ADJ76_04120   Actinomyces meyeri W712 AKU65049.1     9
 ADJ76_04560   Actinomyces meyeri W712 AKU65121.1     13
 ADJ76_01210   Actinomyces meyeri W712 AKU64565.1     5
 ADJ76_02565   Actinomyces meyeri W712 AKU64798.1     11
 ADJ76_06270   Actinomyces meyeri W712 AKU65967.1     31
 ADJ76_00480   Actinomyces meyeri W712 AKU65833.1     30
 AN27039_2522 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85592.1     10
 AN27039_1999 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85069.1     9
 AN27039_2005 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85075.1     3
 AN27039_1131 (fragment)   Actinomyces naeslundii ATCC 27039 BAV84201.1     13
 AN27039_1134 (fragment)   Actinomyces naeslundii ATCC 27039 BAV84204.1     13
 AN27039_1967 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85037.1     31
 AN27039_0153 (fragment)   Actinomyces naeslundii ATCC 27039 BAV83223.1     5
 AN27039_0152 (fragment)   Actinomyces naeslundii ATCC 27039 BAV83222.1     5
 AN27039_2004 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85074.1     3
 AN27039_2097 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85167.1     30
 AN27039_2003   Actinomyces naeslundii ATCC 27039 BAV85073.1     16
 AN27039_1133 (fragment)   Actinomyces naeslundii ATCC 27039 BAV84203.1     13
 AN27039_1130 (fragment)   Actinomyces naeslundii ATCC 27039 BAV84200.1     13
 AN27039_0760 (fragment)   Actinomyces naeslundii ATCC 27039 BAV83830.1    
 AN27039_2008 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85078.1     11
 AN27039_2525 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85595.1     11
 AN27039_2524 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85594.1     26
 AN27039_1132 (fragment)   Actinomyces naeslundii ATCC 27039 BAV84202.1     13
 AN27039_0964 (fragment)   Actinomyces naeslundii ATCC 27039 BAV84034.1     4
 AN27039_2007 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85077.1     11
 AXE84_08940   Actinomyces oris T14V AMD99526.1     30
 AXE84_10510   Actinomyces oris T14V AMD99794.1     10
 AXE84_08560   Actinomyces oris T14V AMD99459.1     9
 AXE84_08570   Actinomyces oris T14V AME00269.1     16
 AXE84_04820   Actinomyces oris T14V AMD98817.1     4
 AXE84_08575   Actinomyces oris T14V AMD99461.1     3
 AXE84_05410   Actinomyces oris T14V AMD98913.1     13
 AXE84_03910   Actinomyces oris T14V AMD98668.1    
 AXE84_10520 (fragment)   Actinomyces oris T14V AMD99795.1     11
 AXE84_01530   Actinomyces oris T14V AMD98267.1     5
 AXE84_10515   Actinomyces oris T14V AME00304.1     26
 AXE84_08585   Actinomyces oris T14V AMD99463.1     11
 AXE84_08430   Actinomyces oris T14V AMD99436.1     31
 AXF14_00820   Actinomyces radicidentis CCUG 36733 AMD86411.1     3
 AXF14_00830   Actinomyces radicidentis CCUG 36733 AMD88332.1     9
 AXF14_00825   Actinomyces radicidentis CCUG 36733 AMD88331.1     16
 AXF14_03995   Actinomyces radicidentis CCUG 36733 AMD88412.1     13
 AXF14_04000   Actinomyces radicidentis CCUG 36733 AMD86910.1     13
 AXF14_08500   Actinomyces radicidentis CCUG 36733 AMD87618.1     29
 AXF14_04915   Actinomyces radicidentis CCUG 36733 AMD87054.1     30
 AXF14_00950   Actinomyces radicidentis CCUG 36733 AMD86429.1     31
 AXF14_01000   Actinomyces radicidentis CCUG 36733 AMD86436.1     30
 AXF14_04875   Actinomyces radicidentis CCUG 36733 AMD87047.1     4
 AXF14_00810   Actinomyces radicidentis CCUG 36733 AMD88330.1     11
 AXF14_09700   Actinomyces radicidentis CCUG 36733 AMD88545.1     21
 AXF14_08485   Actinomyces radicidentis CCUG 36733 AMD87615.1    
 AXF14_10070   Actinomyces radicidentis CCUG 36733 AMD88553.1     26
 SAMN04489714_0283   Actinomyces radingae DSM 9169 SDT86273.1     30
 SAMN04489714_1336   Actinomyces radingae DSM 9169 SDT97203.1     16
 SAMN04489714_0967   Actinomyces radingae DSM 9169 SDT92733.1     26
 SAMN04489714_0916   Actinomyces radingae DSM 9169 SDT92173.1    
 SAMN04489714_1054   Actinomyces radingae DSM 9169 SDT93755.1    
 SAMN04489714_1335   Actinomyces radingae DSM 9169 SDT97185.1     3
 SAMN04489714_1905   Actinomyces radingae DSM 9169 SDU05796.1    
 SAMN04489714_0968   Actinomyces radingae DSM 9169 SDT92745.1     11
 SAMN04489714_0966   Actinomyces radingae DSM 9169 SDT92719.1     10
 SAMN04489714_1338   Actinomyces radingae DSM 9169 SDT97228.1     9
 SAMN04489714_1330   Actinomyces radingae DSM 9169 SDT97114.1     11
 CHIBA101_0107   Actinomyces sp. Chiba101 BAW91982.1     13
 CHIBA101_0824   Actinomyces sp. Chiba101 BAW92690.1     11
 CHIBA101_1824   Actinomyces sp. Chiba101 BAW93657.1     31
 CHIBA101_0818   Actinomyces sp. Chiba101 BAW92684.1     9
 CHIBA101_2346   Actinomyces sp. Chiba101 BAW94167.1     4
 CHIBA101_0802 (fragment)   Actinomyces sp. Chiba101 BAW92668.1    
 CHIBA101_0367   Actinomyces sp. Chiba101 BAW92238.1    
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