Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (54252); Uniprot accession (7858); PDB accession (465); 3D entries (110); cryst (2)
All (49476) Archaea (367) Bacteria (45982) Eukaryota (2997) unclassified (130) Structure (110 - 2 cryst) Characterized (812)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 460 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 SAMN04489716_8720   Actinoplanes derwentensis DSM 43941 SDT79278.1     11
 SAMN04489716_8472   Actinoplanes derwentensis DSM 43941 SDT78679.1     30
 SAMN04489716_8489   Actinoplanes derwentensis DSM 43941 SDT78721.1     31
 SAMN04489716_0790   Actinoplanes derwentensis DSM 43941 SDS44091.1     32
 SAMN04489716_8613   Actinoplanes derwentensis DSM 43941 SDT79023.1     42
 AFR_37790   Actinoplanes friuliensis DSM 7358 AGZ45812.1     16
 AFR_27100   Actinoplanes friuliensis DSM 7358 AGZ43681.1     16
 AFR_31595   Actinoplanes friuliensis DSM 7358 AGZ44579.1     11
 AFR_24665   Actinoplanes friuliensis DSM 7358 AGZ43199.1     11
 AFR_31585   Actinoplanes friuliensis DSM 7358 AGZ44577.1     10
 AFR_01380   Actinoplanes friuliensis DSM 7358 AGZ38565.1     30
 AFR_03100   Actinoplanes friuliensis DSM 7358 AGZ38909.1    
 AFR_07035   Actinoplanes friuliensis DSM 7358 AGZ39696.1     30
 AFR_10940   Actinoplanes friuliensis DSM 7358 AGZ40477.1     13
 AFR_11495   Actinoplanes friuliensis DSM 7358 AGZ40588.1     30
 AFR_13355   Actinoplanes friuliensis DSM 7358 AGZ40957.1     16
 AFR_19380   Actinoplanes friuliensis DSM 7358 AGZ42148.1     32
 AFR_24190   Actinoplanes friuliensis DSM 7358 AGZ43106.1     3
 AFR_27095   Actinoplanes friuliensis DSM 7358 AGZ43680.1     3
 AFR_27110   Actinoplanes friuliensis DSM 7358 AGZ43683.1     9
 AFR_27730   Actinoplanes friuliensis DSM 7358 AGZ43807.1    
 AFR_27730   Actinoplanes friuliensis DSM 7358 AGZ43807.1     13
 AFR_27735   Actinoplanes friuliensis DSM 7358 AGZ43808.1     30
 AFR_31590   Actinoplanes friuliensis DSM 7358 AGZ44578.1     26
 AFR_33005   Actinoplanes friuliensis DSM 7358 AGZ44859.1     31
 AFR_33140   Actinoplanes friuliensis DSM 7358 AGZ44886.1     30
 GlgB   Actinoplanes missouriensis AAQ01691.1 Q7WUM2   9
 TreS   Actinoplanes missouriensis AAQ01689.1
CBF79183.1
Q7WUM4   16
 AMIS_54560 (TreS)   Actinoplanes missouriensis 431 BAL90676.1     16
 AMIS_54550   Actinoplanes missouriensis 431 BAL90675.1     3
 AMIS_63900   Actinoplanes missouriensis 431 BAL91610.1     11
 AMIS_72480   Actinoplanes missouriensis 431 BAL92468.1     16
 AMIS_60130   Actinoplanes missouriensis 431 BAL91233.1     11
 AMIS_54580 (GlgB)   Actinoplanes missouriensis 431 BAL90678.1     9
 AMIS_57940   Actinoplanes missouriensis 431 BAL91014.1     32
 AMIS_61430   Actinoplanes missouriensis 431 BAL91363.1     21
 AMIS_63880   Actinoplanes missouriensis 431 BAL91608.1     10
 AMIS_63890   Actinoplanes missouriensis 431 BAL91609.1     26
 AMIS_65030   Actinoplanes missouriensis 431 BAL91723.1     42
 AMIS_65760   Actinoplanes missouriensis 431 BAL91796.1     31
 AMIS_65920   Actinoplanes missouriensis 431 BAL91812.1     30
 AMIS_61420   Actinoplanes missouriensis 431 BAL91362.1    
 AMIS_61420   Actinoplanes missouriensis 431 BAL91362.1     13
 AMIS_51170   Actinoplanes missouriensis 431 BAL90337.1     30
 AMIS_48070   Actinoplanes missouriensis 431 BAL90027.1     11
 AMIS_10420   Actinoplanes missouriensis 431 BAL86262.1     30
 AMIS_16540   Actinoplanes missouriensis 431 BAL86874.1     13
 AMIS_17870   Actinoplanes missouriensis 431 BAL87007.1    
 AMIS_18690   Actinoplanes missouriensis 431 BAL87089.1    
 AMIS_23270   Actinoplanes missouriensis 431 BAL87547.1     32
 AMIS_38190   Actinoplanes missouriensis 431 BAL89039.1     30
 AMIS_40190   Actinoplanes missouriensis 431 BAL89239.1    
 L083_6169   Actinoplanes sp. N902-109 AGL19679.1     11
 L083_3877 (GlgX)   Actinoplanes sp. N902-109 AGL17387.1     11
 L083_7162 (MalL)   Actinoplanes sp. N902-109 AGL20672.1     16
 L083_6403 (TreS)   Actinoplanes sp. N902-109 AGL19913.1     31
 L083_1382   Actinoplanes sp. N902-109 AGL14892.1     30
 L083_2217 (AcbE)   Actinoplanes sp. N902-109 AGL15727.1     13
 L083_2860   Actinoplanes sp. N902-109 AGL16370.1     23
 L083_3716   Actinoplanes sp. N902-109 AGL17226.1    
 L083_4517   Actinoplanes sp. N902-109 AGL18027.1     32
 L083_5205 (GlgE)   Actinoplanes sp. N902-109 AGL18715.1     3
 L083_5206 (AglA)   Actinoplanes sp. N902-109 AGL18716.1     16
 L083_5208 (GlgB)   Actinoplanes sp. N902-109 AGL18718.1     9
 L083_5332   Actinoplanes sp. N902-109 AGL18842.1    
 L083_5332   Actinoplanes sp. N902-109 AGL18842.1     13
 L083_5805   Actinoplanes sp. N902-109 AGL19315.1     32
 L083_6167 (TreZ)   Actinoplanes sp. N902-109 AGL19677.1     10
 L083_6168 (TreY)   Actinoplanes sp. N902-109 AGL19678.1     26
 L083_6421   Actinoplanes sp. N902-109 AGL19931.1     30
 L083_0697 (fragment)   Actinoplanes sp. N902-109 AGL14207.1    
 L083_5337   Actinoplanes sp. N902-109 AGL18847.1     30
 L083_5586   Actinoplanes sp. N902-109 AGL19096.1     18
 ACPL_6621 (TreZ)   Actinoplanes sp. SE50/110 AEV87503.1
SLM03320.1
    10
 ACPL_6622 (TreY)   Actinoplanes sp. SE50/110 AEV87504.1
SLM03321.1
    26
 ACPL_1259 (AglC)   Actinoplanes sp. SE50/110 AEV82156.1
SLL97961.1
    30
 ACPL_2033   Actinoplanes sp. SE50/110 AEV82930.1
SLL98733.1
   
 ACPL_2547   Actinoplanes sp. SE50/110 AEV83442.1
SLL99243.1
    30
 ACPL_3988 (AmyA)   Actinoplanes sp. SE50/110 AEV84883.1
SLM00681.1
   
 ACPL_4500   Actinoplanes sp. SE50/110 AEV85391.1
SLM01194.1
   
 ACPL_4688 (GlgX)   Actinoplanes sp. SE50/110 AEV85579.1
SLM01382.1
    11
 ACPL_5329 (GlgE)   Actinoplanes sp. SE50/110 AEV86216.1
SLM02024.1
    3
 ACPL_5330 (TreS)   Actinoplanes sp. SE50/110 AEV86217.1
SLM02025.1
    16
 ACPL_5332 (GlgB)   Actinoplanes sp. SE50/110 AEV86219.1
SLM02027.1
    9
 ACPL_6399 (PulA)   Actinoplanes sp. SE50/110 AEV87281.1
SLM03094.1
   
 ACPL_6399 (PulA)   Actinoplanes sp. SE50/110 AEV87281.1
SLM03094.1
    13
 ACPL_6623 (GlgX)   Actinoplanes sp. SE50/110 AEV87505.1
SLM03322.1
    11
 ACPL_6822 (MalL)   Actinoplanes sp. SE50/110 AEV87704.1
SLM03521.1
    31
 ACPL_6838 (AglA)   Actinoplanes sp. SE50/110 AEV87720.1
SLM03537.1
    30
 ACPL_7518 (TreS)   Actinoplanes sp. SE50/110 AEV88398.1
SLM04221.1
    16
 ACPL_2845   Actinoplanes sp. SE50/110 AEV83740.1
SLL99523.1
    11
 ACPL_5219 (GlgB)   Actinoplanes sp. SE50/110 AEV86106.1
SLM01914.1
   
 ACPL_5621   Actinoplanes sp. SE50/110 AEV86508.1
SLM02315.1
    32
 α-amylase (AcbZ; ACPL_3663)   Actinoplanes sp. SE50/110 CAJ81018.1
AEV84558.1
SLM00358.1
Q27GS8  
 acarbose resistent α-amylase (AcbE;ACPL_3683) 3.2.1.1 Actinoplanes sp. SE50/110 AEV84578.1
CAC02970.1
CAJ81030.1
SLM00378.1
Q27GR6
Q9K5L6
 
 acarviosyltransferase (AcbD; ACPL_3684) 2.4.1.- Actinoplanes sp. SE50/110 CAC02971.1
AAE37556.1
AEV84579.1
CAJ81031.1
SLM00379.1
Q9K5L5   2
 PepI (fragment)   Actinoplanes sp. SN223/29 ABV26718.1 A8QWZ9  
 trehalose synthase (TreS) 5.4.99.16 Actinoplanes sp. SN223/29 ABV26719.1 A8QX00   16
 TreX   Actinoplanes sp. SN223/29 ABV26724.1 A8QX06   11
 malto-oligosyltrehalose synthase (TreY) 5.4.99.15 Actinoplanes sp. SN223/29 ABV26725.1 A8QX07   26
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