Auxiliary Activity Family 17

Activities in FamilyLytic polygalacturonic acid monooxygenase / polygalacturonic acid oxidase (C4-dehydrogenating) (EC 1.14.99.-);
Mechanism monooxygenase
NoteFamily created after the characterization of Phytophthora infestans enzymes by Sabbadin et. al., (PMID:34385392). AA17 are copper-dependent lytic polysaccharide monooxygenases (LPMOs) found in oomycetes; binding and cleavage of homogalacturonan with oxidation of C-4 has been demonstrated for three AA17 LPMOs from Phytophtora infestans; oxidative polygalacturonase; C4-oxidative cleavage of polygalacturonic acid, generating a C4-ketone in a b-position relative to one carboxylic group, resulting in an unstable b-keto acid that undergoes spontaneous decarboxylation and tautomerization
Statistics GenBank accession (88); Uniprot accession (4); PDB accession (1); 3D entries (1); cryst (0)

Last update: 2024-04-25 © Copyright 1998-2024
AFMB - CNRS - Université d'Aix-Marseille