What’s new

The CAZy database introduces CAZac, a new, powerful and searchable descriptor of CAZyme reactions to complement the EC number system. Implemented for glycoside hydrolases, glycoside phosphorylases, transglycosidases, polysaccharide lyases and lytic polysaccharide monooxygenases, CAZac allows complex searches in the CAZy database to uncover the evolution of substrate specificity and mechanisms of CAZymes across families. publication here.
This month, no new family, for the first time in a while... If we missed your newly published family, please feel free to contact us by email or using the dedicated form.

This month, we officialized one novel Polysaccharide Lyase family, PL44, as well as three novel carbohydrate binding modules families : CBM104, CBM105 and CBM106.
PL44, CBM105 and CBM106 notably arose from the works of Profs Changhu Xue and Yaoguang Chang group (Ocean University of China, Qingdao), who gave an amazing talk in the last CBM15 conference in Ghent (Belgia).

This month, we officialized two novel GT families, GT136 and GT137, both discovered by the Wihtfield lab, which exhibit original/rare activities : α-pentose and α-Kdo transferases.
We also created two additional subfamilies for GH13 family, following a bioinformatics analysis by the Janecek lab (to be published in Applied Microbiology and Biotechnology).
These subfamilies, GH13_48 and GH13_49, have been characterized some time ago already, but this analysis highlight their conservation pattern and evolutionary relatedness, as well as another group not characterized to date which could become another subfamily in the future.

This month, no new family, for the first time in a while... If we missed your newly published family, please feel free to contact us by email or using the dedicated form.

After an amazing CBM15 conference in Ghent (Belgia), this month, we officialized two novel CBM families, CBM102 and CBM103, both with laminarin-binding members described by Zühlke and coworkers.
We also implemented the division into subfamilies of the GH123 family.
This was done according to the initial presentation of the two first subfamilies last year by Moreno Prieto and coworkers, recently completed by two additional subfamilies by Sumida and coworkers.
However, please note that their group numbering do not correspond to the subfamily numbering : group 1 is GH123_4 ; group 2 is GH123_5 ; group 3 is GH123_3 ; group 4 is GH123_2 and group GH123 is GH123_1).
Most of these subfamilies (apart GH123_1) were previously classified as GH_nc given their weak signals of homology to characterized GH123(_1) members.