| Mechanism | b-elimination |
|---|---|
| Note | This family groups together polysaccharide lyases active on hyaluronan, gellan and chondroitin sulfate (Helbert et al., PNAS (2019) [PMID=30850540]) |
| External resources | CAZypedia; |
| Statistics | GenBank accession (812); Uniprot accession (3); PDB accession (6); 3D entries (2); cryst (0) |
| Bacteria | ||||||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf | |||
| endo-hyaluronan lyase (BcPL33HA; BcellWH2_04512; BACWH2_4253) | 4.2.2.1 | pubmed |
Bacteroides cellulosilyticus WH2 | ALJ61728.1 | A0A0P0GKX0 | 8R73[A] | 1 | |||
| heparosan lyase (BsPL33Hep; HMPREF1181_01744) (weak activity) | 4.2.2.- | Bacteroides stercoris CC31F | EPH20528.1 | 1 | ||||||
| hyaluronate lyase / chondroitin-sulfate lyase (BtPL33HA; BT_4410; BT4410) | 4.2.2.1 4.2.2.5 |
pubmed pubmed |
Bacteroides thetaiotaomicron VPI-5482 | AAO79515.1 | Q89ZG7 | 8R6Z[A,B] 8R70[A,B] 8R71[A,B] 8R72[A,B] 8R75[A,B] |
1 | |||
| polysaccharide lyase (PoPL33; NCTC13071_00468) (weak activity) | 4.2.2.1 4.2.2.5 4.2.2.19 4.2.2.- |
pubmed pubmed pubmed pubmed |
Segatella oris NCTC13071 | VEH14491.1 | 1 | |||||
| chondroitin AC lyase (Bfo2291; BFO_2291) | 4.2.2.5 | pubmed |
Tannerella forsythia 92A2 | AEW20097.1 | G8UJW9 | 1 | ||||
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