| Mechanism | b-elimination |
|---|---|
| 3D Structure Status | ( α / α ) 6 toroid + anti-parallel β-sheet |
| Note | This family groups together polysaccharide lyases active on hyaluronan, gellan and chondroitin sulfate (Helbert et al., PNAS (2019) [PMID=30850540]) |
| External resources | CAZypedia; |
| Statistics | GenBank accession (875); Uniprot accession (3); PDB accession (6); 3D entries (2); cryst (0) |
| Activity Id | EC# | Activity Name | Residue -2 | Bond -1 | Residue -1 | Reacting Bond | Residue +1 | Bond +1 | Residue +2 | Reactant |
| L356 | 4.2.2.1 | hyaluronate lyase | bDGlcpA | 1,3 | bDGlcpNAc | 1,4 | bDGlcpA | 1,3 | bDGlcpNAc | |
| L359 | 4.2.2.5 | chondroitin AC lyase | bDGlcpA | 1,3 | bDGalpNAc_4/6S | 1,4 | bDGlcpA | 1,3 | bDGalpNAc_4/6S | |
| L368 | 4.2.2.19 | chondroitin B lyase | aLIdopA | 1,3 | bDGalpNAc_4S | 1,4 | aLIdopA | 1,3 | bDGalpNAc_4S | |
| L416 | 4.2.2.- | heparosan lyase | bDGlcpA | 1,4 | aDGlcpNAc | 1,4 | bDGlcpA | 1,4 | aDGlcpNAc | |
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