Polysaccharide Lyase Family 33

Mechanism b-elimination
NoteThis family groups together polysaccharide lyases active on hyaluronan, gellan and chondroitin sulfate (Helbert et al., PNAS (2019) [PMID=30850540])
External resourcesCAZypedia;
Statistics GenBank accession (1210); Uniprot accession (6); PDB accession (6); 3D entries (2); cryst (0)
Activity IdEC#Activity NameResidue -2Bond -1Residue -1 Reacting BondResidue +1Bond +1Residue +2Reactant
L356 4.2.2.1 hyaluronate lyase bDGlcpA 1,3 bDGlcpNAc 1,4 bDGlcpA 1,3 bDGlcpNAc
L359 4.2.2.5 chondroitin AC lyase bDGlcpA 1,3 bDGalpNAc_4/6S 1,4 bDGlcpA 1,3 bDGalpNAc_4/6S
L368 4.2.2.19 chondroitin B lyase aLIdopA 1,3 bDGalpNAc_4S 1,4 aLIdopA 1,3 bDGalpNAc_4S
L371 4.2.2.25 gellan lyase aLRhap 1,3 bDGlcp 1,4 bDGlcpA 1,4 bDGlcp
L416 4.2.2.- heparosan lyase bDGlcpA 1,4 bDGlcpNAc 1,4 bDGlcpA 1,4 bDGlcpNAc
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