| Activities in Family | Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (EC 2.4.1.-); Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (EC 2.4.1.-); Dol-P-Man: Man6GlcNAc2-PP-Dol α-1,2-mannosyltransferase (EC 2.4.1.259); Dol-P-Man: Man7GlcNAc2-PP-Dol α-1,6-mannosyltransferase (EC 2.4.1.260); Dol-P-Man: Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase (EC 2.4.1.261); |
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| Mechanism | Inverting |
| 3D Structure Status | GT-C |
| Note | These enzymes use dolichol-P-mannose as the sugar donor. |
| External resources | Glymap; GPI:PIG-B; GPI:SMP3; |
| Statistics | GenBank accession (2674); Uniprot accession (20); |
| Eukaryota | ||||||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | ||||
| Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (PigB;Pig-B) | 2.4.1.- | Homo sapiens | BAA07709.1 AAH17711.1 ACM85135.1 BAD97050.1 BAG37253.1 BAG57112.1 CAH05352.1 CAH05365.1 CAH05366.1 NP_004846.3 |
B2RBK6 B4DEK1 Q8WVN7 Q92521 |
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| Dol-P-Man: Man6GlcNAc2-PP-Dol/Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase (Alg9;DIBD1;DKFZp586M2420;FLJ21845) | 2.4.1.259 2.4.1.261 |
Homo sapiens | BAB15154.1 AAH09255.1 AAL25798.1 AAP97696.1 BAD18793.1 BAG60945.1 BAG63872.1 CAB66861.1 NP_079016.1 XP_041331.1 |
B4DQI3 B4DYW0 Q6ZMD5 Q9H6U8 |
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| Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Smp3;Pig-Z) | 2.4.1.- | Homo sapiens | BAB14263.1 AAH44640.1 BAG59430.1 CAE90685.1 NP_079439.2 XP_016392.1 XP_067596.1 |
B4DL68 Q86VD9 Q9H9G6 |
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| Dol-P-Man: Man7GlcNAc2-PP-Dol α-1,6-mannosyltransferase (Alg12;PP14673) | 2.4.1.260 | Homo sapiens | AAH01729.1 AAH98562.1 AAL55850.1 AAM94900.1 CAC67488.1 CAC83681.1 CAG30255.1 CAO72064.1 NP_077010.1 |
A0A024R4V6 Q9BV10 Q9BV10 |
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| Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Pig-b;PigB) | 2.4.1.- | Mus musculus | BAA94827.1 AAH52658.1 BAE32195.1 NP_061377.2 |
Q7TQ01 Q9JJQ0 |
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| Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Smp3;YOR149c) | 2.4.1.- | Saccharomyces cerevisiae S288c | AAC49635.1 CAA41123.1 CAA99355.1 NP_014792.1 |
Q04174 | ||||||
| Dol-P-Man: Man6GlcNAc2-PP-Dol/Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase (Alg9;YNL219c;N1295) | 2.4.1.259 2.4.1.261 |
Saccharomyces cerevisiae S288c | CAA65277.1 CAA96122.1 NP_014180.1 |
P53868 | ||||||
| Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Gpi10;Per13;YGL142c) | 2.4.1.- | Saccharomyces cerevisiae S288c | CAA68220.1 CAA42931.1 CAA96854.1 NP_011373.1 |
P30777 | ||||||
| Dol-P-Man: Man7GlcNAc2-PP-Dol α-1,6-mannosyltransferase (Alg12;Tb927.2.4720) | 2.4.1.260 | Trypanosoma brucei brucei TREU927 | AAQ15930.1 AAX80168.1 |
Q586R8 Q7YUW0 |
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