| Activities in Family | GDP-α-D-Manp: β-1,2-D-mannosyltransferase (EC 2.4.1.374); |
|---|---|
| Mechanism | inverting |
| Note | Created after (Sernee et al., Cell Host & Microbe, 2019), in press [PMID=31513773]. The dual activity mannosyltransferases/phosphorylases of six Leishmania proteins allows the management of mannogen (storage polysacharride). Family evolutionary related the bacterial GH130 phosphorylases. |
| Statistics | GenBank accession (729); Uniprot accession (6); PDB accession (6); 3D entries (4); cryst (0) |
| Eukaryota | ||||||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | ||||
| MTP1 (LMXM_10_1230) | 2.4.1.374 | pubmed |
Leishmania mexicana MHOM/GT/2001/U1103 | CBZ24446.1 XP_003872964.1 |
E9AND7 | 6Q4W[A,B] | ||||
| MTP2 (LMXM_10_1240) | 2.4.1.374 | pubmed |
Leishmania mexicana MHOM/GT/2001/U1103 | XP_003872965.1 CBZ24447.1 |
E9AND8 | 6Q4X[A,B] 6Q4Y[A,B] 6Q4Z[A,B] |
||||
| MTP3 (LMXM_10_1250) | 2.4.1.374 | Leishmania mexicana MHOM/GT/2001/U1103 | XP_003872966.1 CBZ24448.1 |
E9AND9 | ||||||
| MTP6 (LMXM_10_1280) | 2.4.1.374 | Leishmania mexicana MHOM/GT/2001/U1103 | CBZ24451.1 XP_003872969.1 |
E9ANE2 | ||||||
| MTP4 (LMXM_10_1260) | 2.4.1.374 | Leishmania mexicana MHOM/GT/2001/U1103 | CBZ24449.1 XP_003872967.1 |
E9ANE0 | 6Q50[A] | |||||
| MTP7 (LMXM_10_1290) | 2.4.1.374 | Leishmania mexicana MHOM/GT/2001/U1103 | CBZ24452.1 XP_003872970.1 |
E9ANE3 | ||||||
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