Mechanism	Inverting e
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Asp+Glu diad
Catalytic Proton Donor	Glu
Note	Created after Anderson et al. (J. Biol. Chem. 2005 280: 7720-7728; PMID:15618227)
External resources	CAZypedia;
Statistics	GenBank accession (616); Uniprot accession (11); PDB accession (19); 3D entries (3); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
blood-group endo-β-1,4-galactosidase (RgGH98; FXV78_04990; RGna_RS10325)	3.2.1.102	Mediterraneibacter gnavus ATCC 29149 JCM6515	QEI31357.1	A7B6A6	7PMO[A,B] 7Q1W[A] 7Q20[A,B]
endo-β-1,4-galactosidase (Sp3GH98; SpBgg98A; EABase; CGSSp3BS71_10403) (blood-group A/B-antigen-specific)	3.2.1.102	Streptococcus pneumoniae SP3-BS71	EDK74349.1	A0A0H2UKY3 A0A0H2UKY4 A5LBQ0 C1CB04	2WMI[A,B] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp 1.90 2WMJ[A,B] α-D-Galp-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp 2.00 2WMK[A,B] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-4)[α-L-Fucp-(1-3)]-β-D-GlcpNAc 1.90 4D6C[A] 1.59 4D6D[A] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-α-D-Galp 1.52 4D6E[A] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp 1.45 4D6F[A] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-3)-β-D-GlcpNAc 2.03 4D6G[A] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-α-D-Galp 1.24 4D6H[A] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-3)-β-D-GlcpNAc 1.65 4D6I[A] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-3)-β-D-GlcpNAc 1.99 4D6J[A] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-4)-β-D-GlcpNAc 1.98 4D71[A] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-4)-β-D-GlcpNAc 1.77 4D72[A] α-D-GalpNAc-(1-3)[α-L-Fucp-(1-2)]-β-D-Galp-(1-4)-β-D-GlcpNAc 2.11
endo-β-1,4-galactosidase (SP_2159; SP2159; Sp4GH98) (LewisY-specific)	3.2.1.102	Streptococcus pneumoniae TIGR4	AAK76213.1 AAY71778.1 NP_346573.1	A0A0H2US34 Q97N96	2WMF[A] 1.50 2WMG[A] α-L-Fucp-(1-2)-β-D-Galp-(1-4)[α-L-Fucp-(1-3)]-β-D-GlcpNAc 2.30 2WMH[A] α-L-Fucp-(1-2)-β-D-Galp 1.70
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