| Mechanism | Inverting and retaining a |
|---|---|
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | Glu for inverting members; Asp for retaining members |
| Catalytic Proton Donor | Glu |
| Note | Created based on a paper by Hughes et al. (2003) Oral Microbiol Immunol. 18:309-312 (PMID: 12930523); *Mechanistic and structural elucidation by Gloster et al. (2008) Chem. Biol., Oct 8 (PMID:18848471); the inverting a-glucosidases (EC 3.2.1.20) could be renamed glucoamylases (EC 3.2.1.3 according to Kitamura et al. (2008) J. Biol. Chem., Nov 3 (PMID:18981178) |
| External resources | CAZypedia; |
| Statistics | GenBank accession (6690); Uniprot accession (13); PDB accession (17); 3D entries (6); cryst (0) |
| Activity Id | EC# | Activity Name | Residue -2 | Bond -1 | Residue -1 | Reacting Bond | Residue +1 | Bond +1 | Residue +2 | Reactant |
| H3 | 3.2.1.3 | amylose exo-a-1,4-glucosidase | [aDGlcp | 1,4 | aDGlcp | 1,4 | aDGlcp | H2O | ||
| H14 | 3.2.1.20 | a-glucosidase | [aDGlcp | 1,X | alcohol | H2O | ||||
| H16 | 3.2.1.22 | a-galactosidase | [aDGalp | 1,X | alcohol | H2O | ||||
| H52 | 3.2.1.70 | dextran exo-a-1,6-glucosidase | [aDGlcp | 1,6 | aDGlcp | 1,6 | aDGlcp | H2O | ||
| H66 | 3.2.1.88 | b-L-arabinopyranosidase | [bLArap | 1,X | alcohol | H2O | ||||
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