Glycoside Hydrolase Family 94

Mechanism	Inverting e
Clan	GH-Q
3D Structure Status	( α / α ) ₆ barrel
Catalytic Nucleophile/Base	phosphate
Catalytic Proton Donor	Asp
Note	Formerly known as glycosyltransferase family GT36; Assigned to a GH family following a paper by Hidaka, Honda, Kitaoka, Nirasawa, Hayashi, Wakagi, Shoun and Fushinobu (Structure (Camb). 2004 Jun;12(6):937-947) (PMID: 15274915) that revealed the evolutionary, structural and mechanistic relationship of these phosphorylases with glycoside hydrolases of clan GH-L.
External resources	CAZypedia;
Statistics	GenBank accession (7657); Uniprot accession (49); PDB accession (50); 3D entries (10); cryst (0)

Summary

Download GH94 (7867) Taxonomic display Structure (10) Characterized (46) Activities in Family (11)

Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
cellodextrin-phosphorylase (Cdp; CtCDP; RtCDP; Cthe_2989)	2.4.1.49	doi	Acetivibrio thermocellus ATCC 27405	ABN54185.1 BAA22081.1	A3DJQ6 O24780 Q93HT8	5NZ7[A,B] 5NZ8[A,B] 8H2K[A,B] 8H2V[A,B] 8H2W[A,B] 8H6H[A,B] 8HNU[A,B] 8XI1[A,B] 8XIL[A,B] 8XIS[A,B] 8YAQ[A,B]
cellobiose phosphorylase (Cbp; CtCBP; RtCBD; Cthe_0275)	2.4.1.20	pubmed	Acetivibrio thermocellus ATCC 27405	ABN51514.1	A3DC35
cellodextrin phosphorylase (Cdp-ym4)	2.4.1.49	pubmed	Acetivibrio thermocellus YM4	BAB71818.1	Q93HT8
cellobiose phosphorylase (Cbp; CtCBP)	2.4.1.20	pubmed	Acetivibrio thermocellus YM4	AAL67138.1	A3DC35 Q8VP44	3QDE[A,B] 8HO7[A,B] 8HO8[A,B] 8HO9[A,B] 8HOB[A,B] 8IYR[A,B]
cellobiose-phosphorylase (Cbp)	2.4.1.20	pubmed	Acetivibrio thermocellus YM4	BAA25846.1	O66383
laminaribiose phosphorylase (ACL_0729;ACL0729)	2.4.1.31	pubmed	Acholeplasma laidlawii PG-8A	ABX81345.1	A9NG65
acholetin phosphorylase (AchP; ACL_1061)	2.4.1.-	pubmed	Acholeplasma laidlawii PG-8A	ABX81671.1	A9NH41
cyclic β-1,2-glucan synthase (Cgs; ChvB; Atu2730)	2.4.1.333	pubmed	Agrobacterium fabrum str. C58	AAK88447.2 AAK88447.1 AAL43711.1 NP_355662.1 NP_533395.1	Q7CWD9	8RF0[A] 8RF9[A] 8RFE[A] 8RFG[A]
mixed-linkage β-glucooligosaccharide phosphorylase (BpGH94MLG; E5259_00910)	2.4.1.-	pubmed	Blautia producta DSM 2950	QMW76265.1	A0A7G5MNS2	8BOU[A,B]
cyclic β-1,2-glucan synthetase / cyclic glucan synthase (Cgs)	2.4.1.333	pubmed	Brucella abortus S19	ACD71661.1 AAC34747.1 AAC34747.2	A0A0F6ANM6 B2S8A8 O85166
cellobiose phosphorylase (Cbp;CgCBP)	2.4.1.20	pubmed	Cellulomonas gilvus ATCC13127	BAA28631.1	O66264	2CQS[A,B] 2CQT[A,B] 3ACS[A,B] 3ACT[A,B] 3AFJ[A,B] 3QFY[A,B] 3QFZ[A,B] 3QG0[A,B]
cellobiose phosphorylase (CbP)	2.4.1.20	doi	Cellulomonas uda DSM 20108	AAQ20920.1	Q7WTR6	3RRS[A,B] 3RSY[A,B] 3S4A[A,B] 3S4B[A,B] 3S4C[A] 3S4D[A]
β-1,2-oligoglucan phosphorylase (EiSOGP; HMPREF9088_0334; RT43_GL001656)	2.4.1.333	pubmed	Enterococcus italicus DSM 15952	EFU74768.1 OJG60645.1 WP_007207355.1
4-O-β-D-glucosyl-N-acetyl-D-glucosamine phosphorylase (IaGP; IALB_1006)	2.4.1.-	pubmed	Ignavibacterium album JCM 16511	AFH48717.1	I0AIB0
β-1,2-oligoglucan phosphorylase (LpSOGP;Cphy_0694)	2.4.1.333	pubmed	Lachnoclostridium phytofermentans ISDg	ABX41081.1	A9KJS6	5H3Z[A,B] 5H40[A,B] 5H41[A,B] 5H42[A,B]
β-1,2-oligoglucan phosphorylase (LiSOGP; SOGP; Lin1839)	2.4.1.333	pubmed	Listeria innocua Clip11262	CAC97070.1 NP_471174.1	Q92AT0
3-O-β-D-glucopyranosyl β-D-glucuronide phosphorylase (PBOR_13355)	2.4.1.392	doi	Paenibacillus borealis DSM 13188	AIQ57809.1	A0A089MMR2
solabiose phosphorylase (PBOR_28850)	2.4.1.389	pubmed	Paenibacillus borealis DSM 13188	AIQ60507.1	A0A089LI24
4-O-β-D-glucosyl-D-galactose phosphorylase (GGalP; PpGGalP; X809_13280)	2.4.1.389	pubmed	Paenibacillus polymyxa CR1	AHC20114.1 AHC20112.2
laminaribiose phosphorylase (LbpA)	2.4.1.31	pubmed	Paenibacillus sp. YM1	BAJ10826.1	D7UT17	6GGY[A,B] 6GH2[A,B] 6GH3[A,B]
cellodextrin phosphorylase (CdpA; Ccel_1439)	2.4.1.49	pubmed	Ruminiclostridium cellulolyticum H10	ACL75793.1	B8I1W7
cellodextrin phisphorylase (CdpC; Ccel_3412)	2.4.1.49	pubmed	Ruminiclostridium cellulolyticum H10	ACL77700.1	B8I1R5
cellobiose phosphorylase (CbpA;Ccel_2109)	2.4.1.20	pubmed	Ruminiclostridium cellulolyticum H10	ACL76454.1	B8I421
cellodextrin phosporylase (CdpB; Ccel_2354)	2.4.1.49	pubmed	Ruminiclostridium cellulolyticum H10	ACL76688.1	B8I5F2
cellobiose phosphorylase (CBP;RaCBP;Rumal_0187)	2.4.1.20	pubmed	Ruminococcus albus 7 = DSM 20455	ADU20744.1	E0LCW6 E6UCF2
cellodextrin phosphorylase (CDP;RaCDP;Rumal_2403)	2.4.1.49	pubmed	Ruminococcus albus 7 = DSM 20455	ADU22883.1	E0L4C3 E6UE18
cellobionic acid phosphorylase 94B (Cep94B;CBAP;SdCBAP;Sde_0906) (Cep94B)	2.4.1.321	pubmed	Saccharophagus degradans 2-40	ABD80168.1	Q21MB1	4ZLE[A] 4ZLF[A] 4ZLG[A] 4ZLI[A]
cellobiose phosphorylase 94A (Cbp;SdCBP;Sde_1318) (Cep94A)	2.4.1.20	pubmed	Saccharophagus degradans 2-40	ABD80580.1	Q21L49
cellobiose phosphorylase (TcCBP; SAMN05444373_103016)	2.4.1.20	doi	Thermoclostridium caenicola DSM 19027	SHJ18487.1
cellodextrin-phosphorylase (CepB;CsCdP)	2.4.1.49	pubmed	Thermoclostridium stercorarium DSM8532	AAC45511.1	P77846
cellobiose-phosphorylase (CepA)	2.4.1.20	pubmed	Thermoclostridium stercorarium NCIB 11754	AAC45510.1	Q59316
cellobiose-phosphorylase (CepA;TM1848;Tmari_1863)	2.4.1.20	pubmed	Thermotoga maritima MSB8	AAD36910.1 AGL50787.1 AHD18255.1 AKE29604.1 NP_229644.1	Q9X2G3 R4P2E1
cellobiose-phosphorylase (CbpA)	2.4.1.20	pubmed	Thermotoga neapolitana DSM 4359	AAB95491.2 ACM22959.1	B9K7M6 O52504
cellobiose phosphorylase (GH94_G)	2.4.1.20	pubmed	uncultured bacterium	QCO92836.1	A0A4P8GF30
cellodextrin phosphorylase (GH94_F)	2.4.1.49	pubmed	uncultured bacterium	QCO92835.1	A0A4P8GE33
laminaribiose phosphorylase (GH94_B)	2.4.1.31	pubmed	uncultured bacterium	QCO92990.1	A0A4P8GFQ2
laminaribiose phosphorylase (GH94_C)	2.4.1.31	pubmed	uncultured bacterium	QCO92945.1 QCO93023.1 QCO93046.1	A0A4P8GE90
cellobiose phosphorylase (GH94_E)	2.4.1.20	pubmed	uncultured bacterium	QCO92799.1	A0A4P8GDW8
cellodextrin phosphorylase (GH94_A)	2.4.1.49	pubmed	uncultured bacterium	QCO92991.1	A0A4P8GG51
cellodextrin phosphorylase (GH94_D)	2.4.1.49	pubmed	uncultured bacterium	QCO92946.1 QCO93024.1 QCO93047.1	A0A4V1E8I4
cellobiose phosphorylase, partial (Cbp1775)	2.4.1.20	doi	uncultured bacterium	XHP21234.1
cellobiose phosphorylase (Cbp1942)	2.4.1.20	doi	uncultured bacterium	XHP21232.1
diacetylchitobiose phosphorylase (ChbP)	2.4.1.280	pubmed	Vibrio furnissii	AAG23740.1	Q9F8X1
chitobiose phosphorylase (ChbP;VpChBP)	2.4.1.280	pubmed	Vibrio proteolyticus	BAC87867.1	Q76IQ9	1V7V[A] 1V7W[A] 1V7X[A]
cellobionic acid phosphorylase (CelAP; NdvB; XCC4077)	2.4.1.321	pubmed	Xanthomonas campestris pv. campestris str. ATCC 33913	AAM43298.1 NP_639416.1	Q8P3J4
Eukaryota
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
cellobionic acid phosphorylase (CelAP;NdvB;NCU09425)	2.4.1.321	pubmed	Neurospora crassa OR74A	EAA28929.1 XP_332117.1	Q7S0S2
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