Mechanism	Inverting e
3D Structure Status	6-stranded β-barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Asp (experimental).
Note	formerly known as cellulase family K; distantly related to plant expansins
External resources	CAZypedia; Expansin; PROSITE;
Statistics	GenBank accession (710); Uniprot accession (102); PDB accession (34); 3D entries (10); cryst (0)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
endo-β-1,4-glucanase (EG27II)	3.2.1.4	Ampullaria crossean	ABR92638.1	A7KMF0	5XBU[A] 1.00 5XBX[A] β-D-Glcp-(1-4)-β-D-Glcp 1.04 5XC4[A] β-D-Glcp-(1-4)-β-D-Glcp 1.42 5XC8[A] β-D-Glcp-(1-4)-β-D-Glcp 1.45 5XC9[A] β-D-Glcp-(1-4)-β-D-Glcp 1.28 5XCA[A] β-D-Glcp-(1-4)-β-D-Glcp 1.35	2
endo-β-1,4-glucanase (Cel;CaCel)	3.2.1.4	Cryptopygus antarcticus	ACV50414.1 ACV50415.1	D3GDK4	5H4U[A,B,C] 2.60	1
endo-β-1,4-glucanase (GtGH45; GLOTRDRAFT_59933)	3.2.1.4	Gloeophyllum trabeum ATCC 11539	EPQ56593.1	S7QB86	8BZQ[A] 1.30	3
endo-β-1,4-glucanase (Egl3)	3.2.1.4	Humicola grisea var. thermoidea	BAA74956.1 AAE55435.1 AAN19009.1	O93782 P43316	1HD5[A] 1.7	1
endo-β-1,4-glucanase V (EGV; EG V; NCE5) (Cel45A)	3.2.1.4	Humicola insolens DSM 1800	CAB42307.1 AAE16508.1 AAN23440.1 AAO30277.1 AAO30279.1 AAX00991.1 AAY74558.1 ABA35703.1 ABN29330.1 CAA01574.1 CAA01681.1 CAA01683.1 CAA01696.1 CAA01698.1 CAJ21530.1	P43316	2ENG[A] 1.50 3ENG[A] β-D-Glcp-(1-4)-β-D-Glcp 1.90 4ENG[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.90	1
endo-β-1,4-glucanase (MaCel45A) (Cel45A)	3.2.1.4	Melanocarpus albomyces	CAD56665.1 AAU96162.1 QCO31627.1	Q8J0K8	1L8F[A] 1.80 1OA7[A] β-D-Glcp-(1-4)-β-D-Glcp 2.0 1OA9[A] 2.0	1
endoglucanase (Eg)	3.2.1.4	Mytilus edulis	CAC59695.1 CAC59694.1	P82186 Q95P02	1WC2[A] 1.2	2
endoglucanase (NcCel45A;NCU05121.1) (Cel45A)	3.2.1.4	Neurospora crassa OR74A	CAD70529.1 EAA27871.1 XP_324478.1	Q1K5M0 Q872Q1	6MVI[A] 1.89 6MVJ[A] β-D-Glcp-(1-4)-β-D-Glcp 1.81	1
endoglucanase V (EGV;PcCel45A) (Cel45A)	3.2.1.4	Phanerochaete chrysosporium K-3	BAG68300.1 AEK06231.1	B3Y002 G0ZPJ6	3X2G[A] 1.00 3X2H[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-α-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 0.99 3X2I[A] 1.60 3X2J[A] 1.30 3X2K[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-α-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.18 3X2L[A] 0.83 3X2M[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-α-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 0.64 3X2N[A] 1.20 3X2O[A] 1.50 3X2P[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.52 4ZM7[A] 0.70 5KJO[A] 1.47 5KJQ[A] β-D-Glcp-(1-4)-β-D-Glcp 1.70	3
endo-β-1,4-glucanase (THITE_2110957)	3.2.1.4	Thermothielavioides terrestris NRRL 8126	AEO64667.1	G2QVH7	5GLX[A] 1.42 5GLY[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-α-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.58 5GM9[A] β-D-Glcp-(1-4)-α-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp 1.36	1
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