Mechanism	Inverting e
3D Structure Status	6-stranded β-barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Asp (experimental).
Note	formerly known as cellulase family K; distantly related to plant expansins. Subfamiles established in (Hornung and Terrapon, 2024) [PMID:37585436]
External resources	CAZypedia; Expansin; PROSITE;
Statistics	GenBank accession (396); Uniprot accession (4); PDB accession (14); 3D entries (2); cryst (0)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
endo-β-1,4-glucanase (GtGH45; GLOTRDRAFT_59933)	3.2.1.4	Gloeophyllum trabeum ATCC 11539	EPQ56593.1	S7QB86	8BZQ[A] 1.30	3
endoglucanase V (EGV;PcCel45A) (Cel45A)	3.2.1.4	Phanerochaete chrysosporium K-3	BAG68300.1 AEK06231.1	B3Y002 G0ZPJ6	3X2G[A] 1.00 3X2H[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-α-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 0.99 3X2I[A] 1.60 3X2J[A] 1.30 3X2K[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-α-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.18 3X2L[A] 0.83 3X2M[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-α-D-Glcp β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 0.64 3X2N[A] 1.20 3X2O[A] 1.50 3X2P[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp 1.52 4ZM7[A] 0.70 5KJO[A] 1.47 5KJQ[A] β-D-Glcp-(1-4)-β-D-Glcp 1.70	3
Top

Last update: 2025-12-16 © Copyright 1998-2025
AFMB - CNRS - Université d'Aix-Marseille