Glycoside Hydrolase Family 33

Mechanism Retaining e
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (12745); Uniprot accession (135); PDB accession (195); 3D entries (34); cryst (0)
Activity IdEC#Activity NameResidue -2Bond -1Residue -1 Reacting BondResidue +1Bond +1Residue +2Reactant
H13 3.2.1.18 a-neuraminidase [aDNeup5NAc 2,X alcohol H2O
H98 3.2.1.124 LPS exo-a-3-deoxy-2-octulosonidase (Kdo hydrolase) [aDKdo 2,X alcohol H2O
H199 3.2.1.- a-(2-keto)-(3-deoxy)-nononic acid hydrolase (KDNase) [aDKdn 2,X alcohol H2O
T328 2.4.1.- trans-sialidase [aDNeup5NAc 2,3 alcohol e-alcohol
L346 4.2.2.15 anhydrosialidase aDNeup5NAc 2,8 aDNeup5NAc 2,8 aDNeup5NAc
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