| Mechanism | Retaining e |
|---|---|
| Clan | GH-A |
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | Glu (experimental) |
| Catalytic Proton Donor | Glu (inferred) |
| Note | Following St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated. |
| External resources | CAZypedia; Gaucher Disease; PRINTS; |
| Statistics | GenBank accession (51); Uniprot accession (18); PDB accession (58); 3D entries (2); cryst (0) |
| Bacteria | ||||||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf | |||
| laminarin-debranching β-1,6-glucosidase (FbGH30; FORMB_24730) | 3.2.1.- | pubmed |
Formosa sp. Hel1_33_131 | AOR29490.1 | A0A1D7Y224 | 1 | ||||
| β-glucosidase / β-glucosylceramidase (SrfJ; STM4426) | 3.2.1.45 | pubmed |
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | AAL23246.1 NP_463287.1 |
H9L4C2 Q9KIJ7 |
2WNW[A,B] | 1 | |||
| Eukaryota | ||||||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf | |||
| acid β-glucosidase 1 / β-glucocerebrosidase 1 (Gba1; Gba; GC; GCase; LOC82008) (lysosomal) | 3.2.1.45 | pubmed |
Homo sapiens | AAA35873.1 AAA35877.1 AAA35880.1 AAC51820.1 AAC63056.1 AAH03356.1 AAQ41981.1 AAQ41982.1 AAT13636.1 AAT13637.1 AAV20581.1 AAY03281.1 AAY03324.1 ABL21565.1 ACH14936.1 ACJ92748.1 ACM85831.1 ACM97663.1 AID60277.1 AID60278.1 AID60279.1 AID60280.1 ASU47376.1 BAA02545.1 BAF84600.1 BAG58248.1 BAG60020.1 BAH12898.1 BAH13232.1 BAH13357.1 BAH13365.1 BAH13467.1 BAH13605.1 CAC41172.1 CAC41173.1 CAD12720.1 CAD12721.1 CAE85438.1 CAI95090.1 NP_000148.1 SJX47168.1 |
A0A068F579 A0A068F658 A0A068F753 A0A068FB60 A0A223PQI4 B2R6A7 B4DHT6 B4DMV8 B7Z6E6 B7Z6S9 B7Z731 B7Z7G9 P04062 |
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|
1 | |||
| β-glucosidase 1 / β-glucocerebrosidase / β-glucosylceramidase (Gba;GBA;Gba1) | 3.2.1.45 | pubmed |
Mus musculus | AAA37671.1 AAH06663.1 AAM66757.1 BAC38609.1 NP_032120.1 |
P17439 | 1 | ||||
| β-glucosidase (Bgx1; BGX1) | 3.2.1.21 | pubmed |
Phytophthora infestans 88069 | AAK19754.1 | Q9AT27 | 1 | ||||
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