Mechanism | Retaining e |
---|---|
Clan | GH-A |
3D Structure Status | ( β / α ) 8 barrel |
Catalytic Nucleophile/Base | Glu (experimental) |
Catalytic Proton Donor | Glu (inferred) |
Note | Following St John et al. [FEBS Letters 584:4435-4441 (2010); PMID: 20932833] several GH5 subfamilies have been reassigned to GH30. The subfamilies in GH30 are now indicated. |
External resources | CAZypedia; Gaucher Disease; PRINTS; |
Statistics | GenBank accession (51); Uniprot accession (18); PDB accession (58); 3D entries (2); cryst (0) |
Activity Id | EC# | Activity Name | Residue -2 | Bond -1 | Residue -1 | Reacting Bond | Residue +1 | Bond +1 | Residue +2 | Reactant |
H15 | 3.2.1.21 | b-glucosidase | [bDGlcp | 1,X | alcohol | H2O | ||||
H32 | 3.2.1.45 | ceramide b-glucosidase | [bDGlcp | 1,X | ceramide | H2O | ||||
H234 | 3.2.1.- | gentiobiose b-1,6-glucosidase | [bDGlcp | 1,6 | DGlcp] | H2O | ||||
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