Mechanism	Retaining (inferred) e
3D Structure Status	( β / α ) 5 ( β ) 3 TIM-like
Catalytic Nucleophile/Base	Asp
Catalytic Proton Donor	Glu
External resources	CAZypedia; PROSITE;
Statistics	GenBank accession (23768); Uniprot accession (93); PDB accession (23); 3D entries (14); cryst (0)

Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
lysozyme (BA3501;BaGH25c)	3.2.1.17	pubmed	Bacillus anthracis str. Ames	AAP27267.1 NP_845781.1	A0A3P1U4Q1 A0A6L7H2K3 Q81YN8	2WAG[A]
bacteriolytic enzyme (PlyPH;BA2805)	3.2.1.17	pubmed	Bacillus anthracis str. Ames	AAP26640.1 NP_845154.1	A0A2P0HFC3 A0A6L8NZR3 A0AAC8SCM6 Q81PJ7
lysozyme CH/muramidase (CAC0554)	3.2.1.17	pubmed	Clostridium acetobutylicum ATCC 824	AAA23250.1 AAK78533.1 NP_347193.1	P34020
lyzozyme (SleM)	3.2.1.17	pubmed	Clostridium perfringens S40	BAA20125.1	O06496	5JIP[A,B]
lysozyme (CPE1314)	3.2.1.17	pubmed	Clostridium perfringens str. 13	BAB81020.1 NP_562230.1	I1SBA5 O06496
N-acetylmuramidase (AtlC;EF1992)	3.2.1.17	pubmed	Enterococcus faecalis V583	AAO81737.1 AAR58131.1 NP_815667.1	Q833G2
N-acetylmuramidase (AtlB;EF0355)	3.2.1.17	pubmed	Enterococcus faecalis V583	AAO80218.1 NP_814147.1	Q838S8
lysozyme (LysL)	3.2.1.17	pubmed	Lactococcus lactis subsp. lactis	CAA10710.1	Q9ZEK6
cell wall lytic enzyme (LysA)	3.2.1.17	pubmed	Limosilactobacillus fermentum BR11	AAS57574.1	Q64J93
autolysin (AtlA)	3.2.1.17	pubmed	Streptococcus criceti E49	BAH11115.1	B7X9H1
autolysin (AmL)	3.2.1.17	pubmed	Streptococcus mutans C67-1	BAF03559.1	Q0KK88
β-1,4-N-acetylmuramidase (LytC)	3.2.1.17	pubmed	Streptococcus pneumoniae M31	CAA08765.1 AAQ38109.1 AAY71755.1	Q9Z4J8
autolytic lysozyme (LytC;spr1431)	3.2.1.17	pubmed	Streptococcus pneumoniae R6	AAL00235.1	Q8DP07	2WW5[A] 2WWC[A] 2WWD[A]
lysozyme (Cellosyl)	3.2.1.17	pubmed	Streptomyces coelicolor MULLER			1JFX[A]
lysozyme CH / M1 (M1L; ACM)	3.2.1.17	doi	Streptomyces globisporus ATCC 21553	AAA26687.1	P25310
Eukaryota
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
GH25 muramidase	3.2.1.17	pubmed	Arcopilus cupreus	QNJ46215.1	A0A7S6K784
GH25 muramidase	3.2.1.17	pubmed	Ascobolus sp.	QNJ46252.1	A0A7S6G7K8
GH25 muramidase	3.2.1.17	pubmed	Ascobolus sp.	QNJ46241.1	A0A7S6G7X6
GH25 muramidase	3.2.1.17	pubmed	Aspergillus deflectus	QNJ46212.1	A0A7S6K3Z8
GH25 muramidase	3.2.1.17	pubmed	Aspergillus inflatus	QNJ46248.1	A0A7S6G7I7
lysozyme (AN6470.2)	3.2.1.17	pubmed	Aspergillus nidulans FGSC A4	EAA58492.1 ABF50879.1	A0A1U8QG74 C8V058 G5EAV9 Q5AZ10
GH25 muramidase	3.2.1.17	pubmed	Aspergillus sp.	QNJ46219.1	A0A7S6G7I4
GH25 muramidase	3.2.1.17	pubmed	Blackwellomyces cardinalis	QNJ46231.1	A0A7S6K8D4
lysozyme CH	3.2.1.17	pubmed	Chalara sp.		P00721
GH25 muramidase	3.2.1.17	pubmed	Coniochaeta sp.	QNJ46234.1	A0A7S6G7I9
GH25 muramidase	3.2.1.17	pubmed	Coniothyrium sp.	QNJ46242.1	A0A7S6K403
GH25 muramidase	3.2.1.17	pubmed	Cordyceps farinosa	QNJ46225.1	A0A7S6G7J0
GH25 muramidase	3.2.1.17	pubmed	Curreya sp.	QNJ46240.1	A0A7S6G7J7
GH25 muramidase	3.2.1.17	pubmed	Daldinia fissa	QNJ46235.1	A0A7S6G7S9
GH25 muramidase	3.2.1.17	pubmed	Deconica coprophila	QNJ46222.1	A0A7S6G7J2
lysozyme 1 (EHI_199110)	3.2.1.17	pubmed	Entamoeba histolytica HM-1:IMSS	EAL47908.1 CAA60916.1	C4LWV6 Q27650
GH25 muramidase	3.2.1.17	pubmed	Flammulina velutipes KACC42780	QNJ46237.1	A0A7S6G7K2
GH25 muramidase	3.2.1.17	pubmed	Hamigera paravellanea	QNJ46238.1	A0A7S6G7I8
GH25 muramidase	3.2.1.17	pubmed	Hypholoma polytrichi	QNJ46260.1	A0A7S6K794
GH25 muramidase	3.2.1.17	pubmed	Hypoxylon sp.	QNJ46254.1	A0A7S6K8W7
GH25 muramidase	3.2.1.17	pubmed	Hypoxylon sp.	QNJ46255.1	A0A7S6G7K5
GH25 muramidase	3.2.1.17	pubmed	Lecanicillium sp.	QNJ46224.1	A0A7S6K8V9
GH25 muramidase	3.2.1.17	pubmed	Lecanicillium sp.	QNJ46223.1	A0A7S6G7H9
GH25 muramidase	3.2.1.17	pubmed	Lecanicillium sp.	QNJ46227.1	A0A7S6K400
GH25 muramidase	3.2.1.17	pubmed	Malbranchea flava	QNJ46229.1	A0A7S6G7W8
GH25 muramidase	3.2.1.17	pubmed	Metapochonia bulbillosa	QNJ46239.1	A0A7S6K8W3
GH25 muramidase	3.2.1.17	pubmed	Metarhizium sp.	QNJ46249.1	A0A7S6G7J9
GH25 muramidase	3.2.1.17	pubmed	Mucoromycotina sp.	QNJ46253.1	A0A7S6G7K0
GH25 muramidase	3.2.1.17	pubmed	Neurospora cratophora	QNJ46256.1	A0A7S6G7Y0
GH25 muramidase	3.2.1.17	pubmed	Onygena equina	QNJ46220.1	A0A7S6G7S4
GH25 muramidase	3.2.1.17	pubmed	Paecilomyces sp. (in: Hypocreales)	QNJ46217.1	A0A7S6G7W1
GH25 muramidase	3.2.1.17	pubmed	Paecilomyces sp. (in: Hypocreales)	QNJ46218.1	A0A7S6G7H1
GH25 muramidase	3.2.1.17	pubmed	Paracremonium inflatum	QNJ46245.1	A0A7S6K789
GH25 muramidase	3.2.1.17	pubmed	Parengyodontium album	QNJ46230.1	A0A7S6K785
GH25 muramidase	3.2.1.17	pubmed	Penicillium citrinum	QNJ46221.1	A0A7S6G7I3
GH25 muramidase	3.2.1.17	pubmed	Penicillium sp. qii	QNJ46228.1	A0A7S6K840
GH25 muramidase	3.2.1.17	pubmed	Podospora bulbillosa	QNJ46214.1	A0A7S6G7V7
GH25 muramidase	3.2.1.17	pubmed	Poronia punctata	QNJ46210.1	A0A7S6G7I2
GH25 muramidase	3.2.1.17	pubmed	Poronia punctata	QNJ46209.1	A0A7S6K8V3
GH25 muramidase	3.2.1.17	pubmed	Protostropharia semiglobata	QNJ46257.1	A0A7S6K406
GH25 muramidase	3.2.1.17	pubmed	Protostropharia semiglobata	QNJ46258.1	A0A7S6K850
GH25 muramidase	3.2.1.17	pubmed	Protostropharia semiglobata	QNJ46259.1	A0A7S6G7Y2
GH25 muramidase	3.2.1.17	pubmed	Purpureocillium lilacinum	QNJ46232.1	A0A179GAU8
GH25 muramidase	3.2.1.17	pubmed	Pycnidiophora sp.	QNJ46213.1	A0A7S6K835
GH25 muramidase	3.2.1.17	pubmed	Rhizomucor pusillus	QNJ46208.1	A0A7S6G7H2
GH25 muramidase	3.2.1.17	pubmed	Rosellinia sp.	QNJ46236.1	A0A7S6G7J1
GH25 muramidase	3.2.1.17	pubmed	Sesquicillium rossmaniae	QNJ46247.1	A0A7S6G7X5
GH25 muramidase	3.2.1.17	pubmed	Simplicillium obclavatum	QNJ46250.1	A0A7S6G7T6
GH25 muramidase (AaMur)	3.2.1.17	pubmed	Sodiomyces alcalophilus JCM 7366	QNJ46261.1	A0A7S6K8E4	6ZM8[A]
GH25 muramidase	3.2.1.17	pubmed	Sporormia fimetaria	QNJ46216.1	A0A7S6K8C8
GH25 muramidase	3.2.1.17	pubmed	Thermoascus aurantiacus	QNJ46251.1	A0A7S6G7K1
GH25 muramidase	3.2.1.17	pubmed	Thermomucor indicae-seudaticae	QNJ46226.1	A0A7S6G7W7
GH25 muramidase (TzMur)	3.2.1.17	pubmed	Trichobolus zukalii	QNJ46207.1	A0A7S6G7I6	6ZMV[A,B]
GH25 muramidase	3.2.1.17	pubmed	Umbelopsis westeae	QNJ46233.1	A0A7S6G7H8
GH25 muramidase	3.2.1.17	pubmed	Westerdykella sp.	QNJ46244.1	A0A7S6G7X7
GH25 muramidase	3.2.1.17	pubmed	Xylariaceae sp.	QNJ46246.1	A0A7S6K8D9
GH25 muramidase	3.2.1.17	pubmed	Yunnania penicillata	QNJ46243.1	A0A7S6K843
GH25 muramidase	3.2.1.17	pubmed	Zopfiella sp.	QNJ46211.1	A0A7S6G7W5
Viruses
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
lysin (PlyB)	3.2.1.17	pubmed	Bacteriophage sp. BcpI			2NW0[B] 2NW0[A]
endolysin (CTP1L;phiCTP1_gp29)	3.2.1.17	pubmed	Clostridium phage phiCTP1	ADL40330.1	D9ZNF3	5A6S[A]
muramidase / endolysin (Psm;CPR_C0050)	3.2.1.17	pubmed	Clostridium perfringens SM101	ABG87925.1	Q0SPG7	4KRT[A,B] 4KRU[A]
endolysin (Mur-LH)	3.2.1.17	pubmed	Lactobacillus phage f-0303	AAQ06663.1	Q71JA9
endolysin (Mur)	3.2.1.17	pubmed	Lactobacillus phage LL-H	AAC00557.1	Q38359
lysozyme CH	3.2.1.17	pubmed	Lactobacillus phage mv1	AAA32264.1	P33486
lysin (Lys)	3.2.1.17	pubmed	Lactobacillus phage phiadh	CAB52540.1 NP_050170.1	Q38317
endolysin (Lyb5)	3.2.1.17	pubmed	Lactobacillus phage phiPYB5	ABP88927.1	A5A5E0
peptidoglycan endolysin	3.2.1.17	pubmed	Streptococcus phage B30	AAN28166.2	Q8HA43
lysozyme / endolysin / muramidase (Cpl-7;Cpl7)	3.2.1.17	pubmed	Streptococcus phage CP-7	AAA72844.2 CDS43823.1	A0A068YG91 P19385
lysozyme	3.2.1.17	pubmed	Streptococcus phage CP-9	AAA72845.1	P19386
lysozyme (Cpl1;Cpl-1)	3.2.1.17	pubmed	Streptococcus phage Cp1	AAA32204.1 CAA87744.1 NP_044837.1	P15057	1H09[A] 1OBA[A] 2IXU[A] 2IXV[A] 2J8F[A] 2J8G[A]
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