| Mechanism | Retaining e |
|---|---|
| Clan | GH-K |
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | carbonyl oxygen of C-2 acetamido group of substrate |
| Catalytic Proton Donor | Glu |
| External resources | CAZypedia; HOMSTRAD; PRINTS; Tay-Sachs Disease; |
| Commercial Enzyme Provider(s) | MEGAZYME; |
| Statistics | GenBank accession (23495); Uniprot accession (191); PDB accession (122); 3D entries (38); cryst (0) |
| Activity Id | EC# | Activity Name | Residue -2 | Bond -1 | Residue -1 | Reacting Bond | Residue +1 | Bond +1 | Residue +2 | Reactant |
| H38 | 3.2.1.52 | b-N-acetylhexosaminidase | [bDGlcpNAc/bDGalpNAc | 1,X | alcohol | H2O | ||||
| H39 | 3.2.1.53 | b-N-acetylgalactosaminidase | [bDGalpNAc | 1,X | alcohol | H2O | ||||
| H73 | 3.2.1.96 | mannosyl-oligosaccharide endo-b-1,4-N-acetylglucosaminidase | bDManp | 1,4 | bDGlcpNAc | 1,4 | bDGlcpNAc | 1,X | Asn | H2O |
| H111 | 3.2.1.140 | antigen b-1,3-lacto-N-biosidase | [bDGalp | 1,3 | bDGlcpNAc | 1,3 | bDGalp | 1,X | alcohol | H2O |
| H171 | 3.2.1.- | poly-N-acetylglucose endo-b-1,6-N-acetylglucosaminidase | bDGlcpNAc | 1,6 | bDGlcpNAc | 1,6 | bDGlcpNAc | 1,6 | bDGlcpNAc | H2O |
| H219 | 3.2.1.- | b-N-Acetyl-(6-sulfo)-glucosaminidase | [bDGlcpNAc_6S | 1,X | alcohol | H2O | ||||
| H418 | 3.2.1.- | poly-N-acetylglucose exo-b-1,6-N-acetylglucosaminidase | [bDGlcpNAc | 1,6 | bDGlcpNAc | 1,6 | bDGlcpNAc | H2O | ||
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