Mechanism	Retaining a
Clan	GH-H
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	New: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resources	CAZypedia; EBI Protein of the Month; PDB Molecule of the Month;
Statistics	GenBank accession (217052); Uniprot accession (1018); PDB accession (722); 3D entries (174); cryst (2)

Activity Id	EC#	Activity Name	Residue -2	Bond -1	Residue -1	Reacting Bond	Residue +1	Bond +1	Residue +2	Reactant
H1	3.2.1.1	amylose endo-a-1,4-glucosidase	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	H2O
H3	3.2.1.3	amylose exo-a-1,4-glucosidase			[aDGlcp	1,4	aDGlcp	1,4	aDGlcp	H2O
H8	3.2.1.10	oligo exo-a-1,6-glucosidase			[aDGlcp	1,6	aDGlcp	1,X	aDGlcp	H2O
H14	3.2.1.20	a-glucosidase			[aDGlcp	1,X	alcohol			H2O
H21	3.2.1.28	trehalose a-1,1-glucosidase			[aDGlcp	1,1	aDGlcp]			H2O
H31	3.2.1.41	pullulan endo-a-1,6-glucosidase	aDGlcp	1,4	aDGlcp	1,6	aDGlcp	1,4	aDGlcp	H2O
H34	3.2.1.48	sucrose a-1,2-glucosidase			[aDGlcp	1,2	bDFruf]			H2O
H40	3.2.1.54	cyclomaltodextrin endo-a-1,4-glucosidase	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp(cyclic)	H2O
H45	3.2.1.60	amylose exo-a-1,4-glucotetraosidase	[(aDGlcp)3	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	H2O
H51	3.2.1.68	starch endo-a-1,6-glucosidase	aDGlcp	1,4	aDGlcp	1,6	(aDGlcp-1,4)aDGlcp	1,4	aDGlcp	H2O
H52	3.2.1.70	dextran exo-a-1,6-glucosidase			[aDGlcp	1,6	aDGlcp	1,6	aDGlcp	H2O
H70	3.2.1.93	phosphotrehalose a-1,1-(6 phospho)-glucosidase			[aDGlcp_6P	1,1	aDGlcp]			H2O
H75	3.2.1.98	amylose exo-a-1,4-glucohexaosidase	[(aDGlcp)5	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	H2O
H91	3.2.1.116	amylose exo-a-1,4-glucotriosidase	[(aDGlcp-1,4)aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	H2O
H107	3.2.1.133	amylose exo-a-1,4-glucobiosidase	[aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	H2O
H108	3.2.1.135	pullulan exo-a-1,4-panosidase	[(aDGlcp-1,6)aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	H2O
H112	3.2.1.141	maltotrehalose a-1,4-glucosidase	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,1	aDGlcp]	H2O
H182	3.2.1.-	amylose exo-1,4-glucopentaosidase	[(aDGlcp)4	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	H2O
H191	3.2.1.-	palatin a-1,6-glucosidase			[aDGlcp	1,6	DFruf]			H2O
H196	3.2.1.-	cyclic maltosyl-maltose a-1,6-glucosidase	aDGlcp	1,4	aDGlcp	1,6	aDGlcp	1,4	aDGlcp(cyclic)	H2O
T264	2.4.1.7	sucrose phosphorylase			[aDGlcp	1,2	bDFruf]			aPi
T283	2.4.1.329	sucrose 6'-phosphate phosphorylase			[aDGlcp	1,2	bDFruf_6P]			aPi
T289	2.4.1.352	a-glucosyl-glycerate phosphorylase			[aDGlcp	1,X	glycerate]			aPi
T290	2.4.1.359	a-glucosyl-glycerol phosphorylase			[aDGlcp	1,X	glycerol]			aPi
T292	2.4.99.16	starch phosphorylase	[aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	aPi
T302	2.4.1.-	a-glucoside phosphorylase			[aDGlcp	1,X	alcohol			aPi
T304	2.4.1.4	amylosucrase			[aDGlcp	1,4	aDGlcp	1,4	aDGlcp	a-1,2-bDFruf]
T308	2.4.1.18	1,4-a-glucan branching enzyme	aDGlcp	1,4	aDGlcp	1,6	aDGlcp	1,4	aDGlcp	a-1,4-aDGlcp
T309	2.4.1.19	cyclomaltodextrin glucanotransferase	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp(cyclic)	a-1,4-aDGlcp
T311	2.4.1.25	4-a-glucanotransferase	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	a-1,4-aDGlcp
T318	2.4.1.161	oligosaccharide 4-a-D-glucosyltransferase			[aDGlcp	1,4	aDGlcp	1,4	aDGlcp	a-1,4-aDGlcp
T323	2.4.1.-	a-glucosyltransferase			[aDGlcp	1,X	hydroquinone			a-1,4-DGlcp]
T327	2.4.1.-	a-1,6-maltooligosyltransferase	aDGlcp	1,4	aDGlcp	1,6	aDGlcp	1,4	aDGlcp(cyclic)	a-1,4-aDGlcp
T334	2.4.1.-	acarviosyltransferase	myo-inositol	X,4	aDQuip_4N	1,4	aDGlcp	1,X	alcohol	a-1,4-aDGlcp
T338	2.4.1.-	a-maltosyltransferase	[aDGlcp	1,4	aDGlcp	1,4	aDGlcp	1,4	aDGlcp	a-1,4-aDGlcp
T342	2.4.1.-	sucrose a-transglucosidase			[aDGlcp	1,X	alcohol			a-1,2-bDFruf]
M348	5.4.99.11	isomaltulose synthase			[aDGlcp	1,6	DFruf]			a-1,2-DbFruf]
M349	5.4.99.15	malto-oligosyltrehalose synthase	aDGlcp	1,4	aDGlcp	1,1	aDGlcp]			a-1,4-aDGlcp
M350	5.4.99.16	trehalose synthase / maltose glucosylmutase			[aDGlcp	1,1	aDGlcp]			a-1,4-DGlcp]
H407	3.2.1.-	maltose a-1,4-glucosidase			[aDGlcp	1,4	DGlcp]			H2O
H435	3.2.1.-	acarbose a-1,4-glucosidase	aDQuip_4N	1,4	aDGlcp	1,4	DGlcp]			H2O
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