| Mechanism | Retaining e |
|---|---|
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | carbonyl oxygen of C-2 acetamido group of substrate |
| Catalytic Proton Donor | Glu |
| Note | Created after (Sumida et al., 2011) [PMID: 21297160]. Subfamilies established according to both (Moreno Prieto et al., 2024) [PMID:38129294] and (Sumida et al., 2024) [PMID:38730244]. In the latter, group 1 is GH123_4; group 2 is GH123_5; group 3 is GH123_3; group 4 is GH123_2 and group GH123 is GH123_1. |
| External resources | CAZypedia; |
| Statistics | GenBank accession (480); Uniprot accession (5); PDB accession (5); 3D entries (3); cryst (0) |
| Bacteria | ||||||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf | |||
| exo-β-N-acetylgalactosaminidase (NgaBl; MT990_12505) | 3.2.1.- 3.2.1.- |
pubmed pubmed pubmed pubmed |
Bifidobacterium longum subsp. infantis JRPT | UOG10788.1 | 2 | |||||
| exo-β-N-acetylgalactosaminidase (NgaBf; Bfae_31540) | 3.2.1.- 3.2.1.- |
pubmed doi pubmed doi |
Brachybacterium faecium DSM 4810 | ACU86914.1 WP_015777117.1 |
C7MB27 | 2 | ||||
| exo-β-N-acetylgalactosaminidase (NgaLy) | 3.2.1.- 3.2.1.- |
pubmed pubmed pubmed pubmed |
Lacticaseibacillus yichunensis | WP_125696777.1 | A0AAT8XUB5 | 8K2N[A,B,C,D] | 2 | |||
| β-N-acetylgalactosaminidase (NaNga) (DUF4091 domain-containing protein) | 3.2.1.53 | pubmed |
Niabella aurantiaca DSM 17617 | WP_018628640.1 | A0AAJ6N6J1 A0AAT8XUD7 |
8P4L[A,B,C,D,E,F,G,H,I,J,K,L] 8Q8H[A,B,C,D] |
2 | |||
| exo-β-N-acetylgalactosaminidase (NgaP2) | 3.2.1.- 3.2.1.- |
pubmed pubmed pubmed pubmed |
Paenibacillus sp. TS12 | BEL01682.1 | A0AAT8XUB3 | 8K2L[A] 8K2M[A] |
2 | |||
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