What’s new

This month, we would like to highlight 17 bacterial polysaccharide polymerase families, GT119 to GT135, long-overdue but which required in-depth sequence analyses realized by Meitil and coworkers.

This month, we are welcoming a novel GH family, GH189 after the functional and structural characterization by Tanaka et al. (PMID=38300345) of a transglycosidase activity for a module belonging to this family, distantly related to GH144 and GH162. This team also recently deposited a manuscript to bioRxiv about this superfamily. GH189 distinguished by being systematically part of a trimodular proteins involved in the cyclic β-1,2-glucan syntesis pathway, for which another nice manuscript could be found in bioRxiv.

We also released a new GT family, GT118, discovered by Walklett et al. (PMID=38224120), as well as 17 bacterial polysaccharide polymerase families, GT119 to GT135, long-overdue but which required in-depth sequence analyses, to be published in Communications Biology by Meitil and coworkers.

CAZy wishes you a wonderful 2024 year, healthy and full of discoveries !!!
We would like to start this year by a big thank to CAZypedia contributors and organizers, as the lastly released families, described below, already have CAZypedia pages !

This month, we are welcoming a novel GH family, GH188 after the discovery of a NAD+ dependent sulfoquinovosidase active enzyme by Kaur et al. (PMID=38100472).
We also released another CBM family, CBM101 (Mei et al. ; PMID=38010608, discovered by the same laboratory who recently contributed CBM99, CBM100 and GH187.

Also, for those who missed it : end of 2023, we released on CAZy.org our expert annotation of the eukaryotic genomes sequenced by JGI after publication, including both MycoCosm and PhycoCosm projects ! This huge annotation effort is accomplished by Bernard and Elodie. We hope you’ll appreciate it.