Polysaccharide Lyase Family 29

Activities in FamilyChondroitinase B (EC 4.2.2.19);
Chondroitin AC lyase (EC 4.2.2.5);
Mechanism b-elimination
NoteFamily created after Ndeh et al., J. Biol. Chem. (2018) 293:17906-17916 [PMID=30262663] who have shown that the PL29 enzyme BT_3328 of Bacteroides thetaiotaomicron is active on chondroitin sulfate, dermatan sulfate and hyaluronic acid.
Statistics GenBank accession (281); Uniprot accession (1);
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 chondroitin ABC lyase (BT_3328; BT3328) 4.2.2.5
4.2.2.19
pubmed
pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO78434.1 Q8A2H7  
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