Polysaccharide Lyase Family 29

Activities in FamilyHyaluronate lyase (EC 4.2.2.1);
Chondroitinase B (EC 4.2.2.19);
Chondroitin AC lyase (EC 4.2.2.5);
Mechanism b-elimination
NoteFamily created after Ndeh et al., J. Biol. Chem. (2018) 293:17906-17916 [PMID=30262663] who have shown that the PL29 enzyme BT_3328 of Bacteroides thetaiotaomicron is active on chondroitin sulfate, dermatan sulfate and hyaluronic acid.
Statistics GenBank accession (289); Uniprot accession (2);


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