| Activities in Family | Acharan-sulfate lyase (EC 4.2.2.-); Heparin lyase / heparin lyase I (EC 4.2.2.7); Heparin-sulfate lyase / heparin lyase III (EC 4.2.2.8); |
|---|---|
| Mechanism | b-elimination |
| 3D Structure Status | ( α / α ) 6 toroid + anti-parallel β-sheet |
| Note | heparin lyase II enzymes have simultaneously heparin lyase (heparin lyase I) and heparin-sulfate lyase (heparin lyase III) activity ; distantly related to family PL15; |
| Statistics | GenBank accession (86); Uniprot accession (3); PDB accession (4); 3D entries (1); cryst (0) |
| Bacteria | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf |
| acharan sulfate lyase 1/2 / heparin lyase II / heparanase II (AlsI;Als2;HepII) | 4.2.2.- | pubmed |
Bacteroides stercoris HJ-15 | ACN29695.1 | C0JBW5 | 1 | |
| heparin lyase II / heparinase II (HepB;Phep_2408) | 4.2.2.7 4.2.2.8 |
pubmed pubmed |
Pedobacter heparinus DSM 2366 | ACU04612.1 AAB18277.1 ABJ17170.1 ACW20418.1 |
C6XZB6 Q46080 |
2FUQ[A,B] 2FUT[A,B] 3E7J[A,B] 3E80[A,B,C] |
1 |
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