Polysaccharide Lyase Family 18

Activities in FamilyAlginate lyase (EC 4.2.2.-);
Poly-(MG)-lyase / MG-specific alginate lyase (EC 4.2.2.-);
Poly(α-L-guluronate) lyase / G-specific alginate lyase (EC 4.2.2.11);
Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3);
Mechanism b-elimination
3D Structure Statusβ-jelly roll
NoteThe alginate lyase has been demonstrated for several members of this family
Statistics GenBank accession (51); Uniprot accession (4); PDB accession (3); 3D entries (2); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 alginate lyase (AlyM5; JFJ09_20015) 4.2.2.-   Pseudoalteromonas arctica M9 MBZ2194481.1    
 alginate lyase (AlyA) 4.2.2.3
4.2.2.11
pubmed
pubmed
Pseudoalteromonas atlantica AR06 BAI50574.1 D1MX66  
 alginate lyase (partial) 4.2.2.3
4.2.2.11
pubmed
pubmed
Pseudoalteromonas sp. 272   P84143 1J1T[A]
 poly-MG alginate lyase (Aly;alyPEEC) 4.2.2.-
4.2.2.-
pubmed
pubmed
pubmed
pubmed
Pseudoalteromonas sp. IAM14594 AAD16034.1
ACK10595.1
Q9Z6D6  
 bifunctional alginate lyase (Aly;Aly-SJ02) 4.2.2.3
4.2.2.11
pubmed
pubmed
Pseudoalteromonas sp. SM0524 ACB87607.2
ACB87607.1
B2LME8 4Q8K[A]
4Q8L[A,B]
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