| Activities in Family | Hyaluronate lyase (EC 4.2.2.1); |
|---|---|
| Mechanism | b-elimination |
| 3D Structure Status | triple strand β-helix |
| Note | Formerly known as glycoside hydrolase family GH69; assigned to a PL family following papers by Baker, J. R., Dong, S. and Pritchard, D. G. (2002) Biochem J 365, 317-322 and Smith et al (2005) PNAS 102: 17652-17657. Subfamilies have been removed in this family (December 2012). |
| Commercial Enzyme Provider(s) | PROZOMIX; |
| Statistics | GenBank accession (435); Uniprot accession (3); PDB accession (13); 3D entries (5); cryst (0) |
| Bacteria | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| hyaluronate lyase (HylP2) | 4.2.2.1 | pubmed |
Streptococcus pyogenes 10403 | AAA86895.1 | Q54699 Q9A0M7 |
2DP5[A] 3EKA[A] |
|
| hyaluronate lyase (HylP1;SPy0701) | 4.2.2.1 | pubmed |
Streptococcus pyogenes M1 GAS SF370 | AAK33657.1 NP_268936.1 |
Q9A0M7 | 2C3F[A] 2PK1[A] 2YVV[A] 2YW0[A] 2YX2[A] |
|
| Viruses | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| hyaluronate lyase (HylP1;HylP) | 4.2.2.1 | pubmed |
Streptococcus pyogenes phage H4489A | AAA98101.1 | P15316 | 6WV2[A,B,C] 6WWX[A,B,C] 6WXA[A,B,C] 6X3M[A,B,C,D,E,F,G,H,I] |
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