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Polysaccharide Lyase Family 16

Activities in FamilyHyaluronate lyase (EC 4.2.2.1);
Mechanism b-elimination
3D Structure Statustriple strand β-helix
NoteFormerly known as glycoside hydrolase family GH69; assigned to a PL family following papers by Baker, J. R., Dong, S. and Pritchard, D. G. (2002) Biochem J 365, 317-322 and Smith et al (2005) PNAS 102: 17652-17657. Subfamilies have been removed in this family (December 2012).
Commercial Enzyme Provider(s)PROZOMIX;
Statistics GenBank accession (435); Uniprot accession (3); PDB accession (13); 3D entries (5); cryst (0)
Summary
Download PL16 (410) Taxonomic display Structure (5) Characterized (3)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 R0V13_01465 (fragment)   Facklamia hominis UMB2355B WPJ91086.1    
 RCF27_08155 (fragment)   Rhodococcus pyridinivorans CP-8 WMM74250.1    
 P1X07_01045   Streptococcus equi Kargaly-22 WGS35418.1    
 SEQ_2045   Streptococcus equi subsp. equi 4047 CAW95336.1    
 JZI44_03265   Streptococcus equi subsp. equi 470_001 QWB43413.1    
 JZI44_10675   Streptococcus equi subsp. equi 470_001 QWB42821.1    
 JZI56_09885   Streptococcus equi subsp. equi 470_003 QWB40731.1    
 JZI56_02470   Streptococcus equi subsp. equi 470_003 QWB41315.1    
 JZI50_09130   Streptococcus equi subsp. equi 470_006 QWB38524.1    
 JZI50_05730   Streptococcus equi subsp. equi 470_006 QWB37949.1    
 JZI48_05885   Streptococcus equi subsp. equi 470_007 QWB35995.1    
 JZI48_02490   Streptococcus equi subsp. equi 470_007 QWB37257.1    
 JZI59_08395   Streptococcus equi subsp. equi 470_008 QWB34470.1    
 JZI59_04995   Streptococcus equi subsp. equi 470_008 QWB35736.1    
 JZI66_01630   Streptococcus equi subsp. equi 489_002 QWB33198.1    
 JZI66_05025   Streptococcus equi subsp. equi 489_002 QWB33770.1    
 JZI57_04250   Streptococcus equi subsp. equi 489_004 QWB20709.1    
 JZI57_00850   Streptococcus equi subsp. equi 489_004 QWB20140.1    
 JZI54_10650   Streptococcus equi subsp. equi 489_005 QWB18075.1    
 JZI54_07255   Streptococcus equi subsp. equi 489_005 QWB17500.1    
 JZI51_03260   Streptococcus equi subsp. equi 489_010 QWB16659.1    
 JZI51_10585   Streptococcus equi subsp. equi 489_010 QWB16070.1    
 SE071780_02165   Streptococcus equi subsp. equi ATCC 39506 ASB97711.1    
 SE071780_00215   Streptococcus equi subsp. equi ATCC 39506 ASB95834.1    
 SE071780_01756   Streptococcus equi subsp. equi ATCC 39506 ASB97343.1    
 RIM75_01155   Streptococcus equi subsp. equi HT1112 WOK49648.1    
 RIM74_01155   Streptococcus equi subsp. equi HTP133 WOK45881.1    
 RIM73_04970   Streptococcus equi subsp. equi HTP232 WOK48419.1    
 RIM73_01155   Streptococcus equi subsp. equi HTP232 WOK47744.1    
 NCTC9682_02201 (fragment)   Streptococcus equi subsp. equi NCTC9682 VEH35905.1    
 NCTC9682_00221 (Hylp3)   Streptococcus equi subsp. equi NCTC9682 VEH29504.1    
 NCTC9682_02200 (fragment)   Streptococcus equi subsp. equi NCTC9682 VEH35901.1    
 RLO20_09645   Streptococcus equi subsp. equi XJ5012 WOK51208.1    
 RIM64_08215   Streptococcus equi subsp. zooepidemicus JMC111 WOK54885.1    
 JFMEOBDD_00533   Streptococcus equi subsp. zooepidemicus SEZ25 QTZ56455.1    
 HCFMJIKG_00547   Streptococcus equi subsp. zooepidemicus SEZ36 QTR95317.1    
 RIM62_08220   Streptococcus equi subsp. zooepidemicus ZHZ211 WOK52939.1    
 hyaluronate lyase (HylP2) 4.2.2.1 Streptococcus pyogenes 10403 AAA86895.1 Q54699
Q9A0M7		 2DP5[A]
3EKA[A]
 GQ677_02480   Streptococcus pyogenes 1085 QHB64130.1    
 GQ677_06105   Streptococcus pyogenes 1085 QHB64795.1    
 GQ677_06545   Streptococcus pyogenes 1085 QHB64879.1    
 C7K40_02100   Streptococcus pyogenes 14GA0832 AXI57526.1    
 DMC40_04250   Streptococcus pyogenes ABC020055975 AYO92582.1    
 DMC40_06955   Streptococcus pyogenes ABC020055975 AYO93086.1    
 DMC40_02060   Streptococcus pyogenes ABC020055975 AYO92182.1    
 DMC40_02935   Streptococcus pyogenes ABC020055975 AYO92346.1    
 SPYALAB49_001176   Streptococcus pyogenes Alab49 AEQ24773.1    
 SPYALAB49_000995   Streptococcus pyogenes Alab49 AEQ24593.1    
 SPYALAB49_001308 (fragment)   Streptococcus pyogenes Alab49 AEQ24901.1    
 SPAP1_06950   Streptococcus pyogenes AP1 AKG28345.1    
 SPAP1_05545   Streptococcus pyogenes AP1 AKG28083.1    
 SPAP1_02840   Streptococcus pyogenes AP1 AKG27558.1    
 SPAP1_03565   Streptococcus pyogenes AP1 AKG27701.1    
 AUQ45_0607 (HylP)   Streptococcus pyogenes AP53 AMY97168.1    
 AUQ45_1317 (fragment)   Streptococcus pyogenes AP53 AMY97871.1    
 AUQ45_1187 (HylP)   Streptococcus pyogenes AP53 AMY97741.1    
 AUQ45_1011 (HylP)   Streptococcus pyogenes AP53 AMY97567.1    
 DP15_245 (Hylp2)   Streptococcus pyogenes ATCC 19615 AIL10687.1    
 DP15_676 (Hylp2)   Streptococcus pyogenes ATCC 19615 AIL11612.1    
 GJE17_02925   Streptococcus pyogenes AUSMDU00010539 QGK05361.1    
 DB248_04545   Streptococcus pyogenes CCUG 4207 QAB34490.1    
 DB248_03100   Streptococcus pyogenes CCUG 4207 QAB34227.1    
 DB248_06550   Streptococcus pyogenes CCUG 4207 QAB34870.1    
 DB248_07280   Streptococcus pyogenes CCUG 4207 QAB35011.1    
 SpyM6D471_07290   Streptococcus pyogenes D471 AKI78395.1    
 SpyM6D471_05370   Streptococcus pyogenes D471 AKI78041.1    
 SpyM6D471_06095   Streptococcus pyogenes D471 AKI78183.1    
 EHF40_06555   Streptococcus pyogenes Duke-Large AZA35611.1    
 ETT46_01340   Streptococcus pyogenes emm100 QCK70271.1    
 ETT46_06180   Streptococcus pyogenes emm100 QCK71163.1    
 ETT46_05335   Streptococcus pyogenes emm100 QCK71001.1    
 ETT68_02860   Streptococcus pyogenes emm105 QCK33544.1    
 ETT67_04010   Streptococcus pyogenes emm11 QCK35399.1    
 ETT67_05910   Streptococcus pyogenes emm11 QCK35745.1    
 ETT44_03695   Streptococcus pyogenes emm197 QCK74061.1    
 ETT44_01995   Streptococcus pyogenes emm197 QCK73751.1    
 ETT44_04515   Streptococcus pyogenes emm197 QCK74217.1    
 ETT61_06555   Streptococcus pyogenes emm22.8 QCK45938.1    
 ETT61_03450   Streptococcus pyogenes emm22.8 QCK45379.1    
 ETT48_06170   Streptococcus pyogenes emm230 QCK67850.1    
 ETT48_04110   Streptococcus pyogenes emm230 QCK67462.1    
 ETT57_06030   Streptococcus pyogenes emm25 QCK52763.1    
 ETT45_04985   Streptococcus pyogenes emm54 QCK72679.1    
 ETT69_03350   Streptococcus pyogenes emm55 QCK31865.1    
 ETT69_07765   Streptococcus pyogenes emm55 QCK32656.1    
 ETT50_06560   Streptococcus pyogenes emm56 QCK64609.1    
 ETT50_05135   Streptococcus pyogenes emm56 QCK64352.1    
 ETT50_03445   Streptococcus pyogenes emm56 QCK64032.1    
 ETT56_03480   Streptococcus pyogenes emm58 QCK54010.1    
 ETT56_06640   Streptococcus pyogenes emm58 QCK54599.1    
 ETT56_05330   Streptococcus pyogenes emm58 QCK54357.1    
 ETT64_05280   Streptococcus pyogenes emm64.3 QCK40702.1    
 ETT64_03530   Streptococcus pyogenes emm64.3 QCK40374.1    
 ETT66_05320   Streptococcus pyogenes emm65 QCK37292.1    
 ETT51_01265   Streptococcus pyogenes emm70 QCK61916.1    
 ETT51_04735   Streptococcus pyogenes emm70 QCK62553.1    
 ETT51_04310   Streptococcus pyogenes emm70 QCK62475.1    
 ETT72_01365   Streptococcus pyogenes emm74 QCK26355.1    
 ETT72_03420   Streptococcus pyogenes emm74 QCK26733.1    
 ETT72_06220   Streptococcus pyogenes emm74 QCK27253.1    
 ETT65_02080   Streptococcus pyogenes emm75.1 QCK39736.1    
 ETT62_06275   Streptococcus pyogenes emm78.3 QCK44793.1    
 ETT63_04110   Streptococcus pyogenes emm89.14 QCK42173.1    
 ETT52_06270   Streptococcus pyogenes emm97.1 QCK61163.1    
 JAN99_03495 (HylP)   Streptococcus pyogenes emm9ST603 QQA64856.1    
 ETT70_04095   Streptococcus pyogenes emmNA QCK30302.1    
 ETT70_05300   Streptococcus pyogenes emmNA QCK30530.1    
 ETT71_01350   Streptococcus pyogenes emmSTG866.1 QCK28127.1    
 AL510_07135   Streptococcus pyogenes FDAARGOS_149 AMH03618.1    
 EGX80_00140   Streptococcus pyogenes FDAARGOS_514 AYZ10371.1    
 EGX80_01525   Streptococcus pyogenes FDAARGOS_514 AYZ08884.1    
 EGX80_00960   Streptococcus pyogenes FDAARGOS_514 AYZ08774.1    
 EGX78_03195   Streptococcus pyogenes FDAARGOS_534 AYZ02517.1    
 EGX78_04495   Streptococcus pyogenes FDAARGOS_534 AYZ02755.1    
 FOB76_01285   Streptococcus pyogenes FDAARGOS_668 QEU35956.1    
 FOB76_09375   Streptococcus pyogenes FDAARGOS_668 QEU37394.1    
 FIU13_10010   Streptococcus pyogenes FDAARGOS_774 QDC78260.1    
 FIU13_08575   Streptococcus pyogenes FDAARGOS_774 QDC77998.1    
 FIU13_01975   Streptococcus pyogenes FDAARGOS_774 QDC76839.1    
 FIU13_02705   Streptococcus pyogenes FDAARGOS_774 QDC76981.1    
 B2G65_03235   Streptococcus pyogenes GUR ASO73760.1    
 B2G65_05975   Streptococcus pyogenes GUR ASO75021.1    
 B2G65_01855   Streptococcus pyogenes GUR ASO73519.1    
 B2G65_03940   Streptococcus pyogenes GUR ASO73894.1    
 CFA72_01855   Streptococcus pyogenes GURSA1 ASO67801.1    
 CFA72_03940   Streptococcus pyogenes GURSA1 ASO68178.1    
 CFA72_03235   Streptococcus pyogenes GURSA1 ASO68044.1    
 CFA72_05975   Streptococcus pyogenes GURSA1 ASO69307.1    
 HKU360_00797   Streptococcus pyogenes HKU360 AIW24615.1    
 L897_04975   Streptococcus pyogenes HSC5 AGQ28519.1    
 L897_07515   Streptococcus pyogenes HSC5 AGQ28627.1    
 L897_05855   Streptococcus pyogenes HSC5 AGQ28574.1    
 JMUB1235_0575   Streptococcus pyogenes JMUB1235 BAV54834.1    
 SPYJRS4_1277 (HylP)   Streptococcus pyogenes JRS4 BAR44777.1
AKI76512.1		    
 SPYJRS4_1529 (Hylp2)   Streptococcus pyogenes JRS4 BAR45029.1
AKI76724.1		    
 SPYJRS4_1119 (Hylp3)   Streptococcus pyogenes JRS4 BAR44619.1
AKI76370.1		    
 CCX85_04985   Streptococcus pyogenes JS12 AUG50481.1    
 SPYKS030_09350   Streptococcus pyogenes KS030 BBB88324.1    
 SPYKS030_07700   Streptococcus pyogenes KS030 BBB88167.1    
 SPYKS030_06570   Streptococcus pyogenes KS030 BBB88055.1    
 hyaluronan lyase (HylP3)   Streptococcus pyogenes M1 GAS SF370 AAK34249.1
NP_269528.1		   2WB3[A]
 hyaluronate lyase (HylP2)   Streptococcus pyogenes M1 GAS SF370 AAK33900.1
NP_269179.1		   2WH7[A]
 hyaluronate lyase (HylP1;SPy0701) 4.2.2.1 Streptococcus pyogenes M1 GAS SF370 AAK33657.1
NP_268936.1		 Q9A0M7 2C3F[A]
2PK1[A]
2YVV[A]
2YW0[A]
2YX2[A]
 FE90_0215   Streptococcus pyogenes M23ND AIQ00984.1    
 FE90_0641 (HylP)   Streptococcus pyogenes M23ND AIQ01408.1    
 FE90_0460 (HylP)   Streptococcus pyogenes M23ND AIQ01229.1    
 FE90_0882 (fragment)   Streptococcus pyogenes M23ND AIQ01645.1    
 FE90_0883 (HylP) (fragment)   Streptococcus pyogenes M23ND AIQ01646.1    
 M3B_0843   Streptococcus pyogenes M3-b BAU60212.1    
 M3B_0510 (fragment)   Streptococcus pyogenes M3-b BAU59891.1    
 M3B_0511 (fragment)   Streptococcus pyogenes M3-b BAU59892.1    
 M3B_0729   Streptococcus pyogenes M3-b BAU60098.1    
 M3B_1017   Streptococcus pyogenes M3-b BAU60386.1    
 EGC57_05930   Streptococcus pyogenes M75 QAZ37222.1    
 AWM58_02775   Streptococcus pyogenes MEW427 AMA68626.1    
 AWM58_05790   Streptococcus pyogenes MEW427 AMA69164.1    
 MGAS10270_Spy0590 or MGAS10270_Spy1310   Streptococcus pyogenes MGAS10270 ABF33655.1
ABF34375.1		    
 M6_Spy1203   Streptococcus pyogenes MGAS10394 AAT87338.1    
 M6_Spy0993 (fragment)   Streptococcus pyogenes MGAS10394 AAT87128.1    
 M6_Spy1550   Streptococcus pyogenes MGAS10394 AAT87685.1    
 M6_Spy0059   Streptococcus pyogenes MGAS10394 AAT86194.1    
 M6_Spy1348   Streptococcus pyogenes MGAS10394 AAT87483.1    
 MGAS10750_Spy0615   Streptococcus pyogenes MGAS10750 ABF37565.1    
 MGAS10750_Spy1285   Streptococcus pyogenes MGAS10750 ABF38235.1    
 MGAS11027_0588   Streptococcus pyogenes MGAS11027 ANC23593.1    
 MGAS1882_1115   Streptococcus pyogenes MGAS1882 AFC68322.1    
 MGAS27061_0575   Streptococcus pyogenes MGAS27061 ANC26858.1    
 DZU27_03400   Streptococcus pyogenes MGAS28533 QBB48450.1    
 HylP.1   Streptococcus pyogenes MGAS315 AAM79332.1
NP_664529.1		    
 HylP.2 (fragment)   Streptococcus pyogenes MGAS315 AAM79536.1
NP_664733.1		    
 HylP.3   Streptococcus pyogenes MGAS315 AAM79708.1
NP_664905.1		    
 HylP.4   Streptococcus pyogenes MGAS315 AAM79821.1
NP_665018.1		    
 HylP.6   Streptococcus pyogenes MGAS315 AAM80025.1
NP_665222.1		    
 SpyM3_0928 (short fragment)   Streptococcus pyogenes MGAS315 AAM79535.1    
 HylP   Streptococcus pyogenes MGAS8232 AAL97134.1
NP_606635.1		    
 HylP   Streptococcus pyogenes MGAS8232 AAL97438.1
NP_606939.1		    
 HylP   Streptococcus pyogenes MGAS8232 AAL97860.1
NP_607361.1		    
 HylP   Streptococcus pyogenes MGAS8232 AAL98032.1
NP_607533.1		    
 HylP   Streptococcus pyogenes MGAS8232 AAL98283.1
NP_607784.1		    
 MGAS9429_Spy0586   Streptococcus pyogenes MGAS9429 ABF31774.1    
 MGAS9429_Spy0843   Streptococcus pyogenes MGAS9429 ABF32031.1    
 NCTC10085_00792   Streptococcus pyogenes NCTC10085 SQG54433.1    
 NCTC10874_01006   Streptococcus pyogenes NCTC10874 SQG15529.1    
 NCTC10876_01282   Streptococcus pyogenes NCTC10876 SQF63080.1    
 NCTC10876_01842 (Hylp3)   Streptococcus pyogenes NCTC10876 SQF63621.1    
 NCTC10876_00807   Streptococcus pyogenes NCTC10876 SQF62617.1    
 NCTC10876_01069   Streptococcus pyogenes NCTC10876 SQF62874.1    
 NCTC10877_00693   Streptococcus pyogenes NCTC10877 SQH10299.1    
 NCTC10879_01088   Streptococcus pyogenes NCTC10879 SQG28395.1    
 NCTC10879_00686   Streptococcus pyogenes NCTC10879 SQG27999.1    
 NCTC10879_01182   Streptococcus pyogenes NCTC10879 SQG28489.1    
 NCTC10879_00855   Streptococcus pyogenes NCTC10879 SQG28167.1    
 NCTC12044_01383   Streptococcus pyogenes NCTC12044 SQH27273.1    
 NCTC12045_00915   Streptococcus pyogenes NCTC12045 SQE97795.1    
 NCTC12046_01148   Streptococcus pyogenes NCTC12046 SQF19819.1    
 NCTC12046_01600   Streptococcus pyogenes NCTC12046 SQF20247.1    
 NCTC12046_01123   Streptococcus pyogenes NCTC12046 SQF19794.1    
 NCTC12047_01474 (HylP)   Streptococcus pyogenes NCTC12047 SQF21921.1    
 NCTC12050_01298 (Hylp3)   Streptococcus pyogenes NCTC12050 SQF16328.1    
 NCTC12050_01007   Streptococcus pyogenes NCTC12050 SQF16048.1    
 NCTC12052_00638   Streptococcus pyogenes NCTC12052 SQF51859.1    
 NCTC12052_01240   Streptococcus pyogenes NCTC12052 SQF52445.1    
 NCTC12052_01068 (fragment)   Streptococcus pyogenes NCTC12052 SQF52274.1    
 NCTC12052_01796 (Hylp3)   Streptococcus pyogenes NCTC12052 SQF52973.1    
 NCTC12057_01008   Streptococcus pyogenes NCTC12057 SQF10000.1    
 NCTC12059_01062   Streptococcus pyogenes NCTC12059 SQE78906.1    
 NCTC12059_00688   Streptococcus pyogenes NCTC12059 SQE78165.1    
 NCTC12060_01035   Streptococcus pyogenes NCTC12060 VED83850.1    
 NCTC12062_01065   Streptococcus pyogenes NCTC12062 SQF27880.1    
 NCTC12062_00694   Streptococcus pyogenes NCTC12062 SQF27065.1    
 NCTC12064_00395   Streptococcus pyogenes NCTC12064 SQF22579.1    
 NCTC12066_00784   Streptococcus pyogenes NCTC12066 SQE93017.1    
 NCTC12067_01393   Streptococcus pyogenes NCTC12067 SQF56221.1    
 NCTC12069_01456   Streptococcus pyogenes NCTC12069 SQF04216.1    
 NCTC12069_01116   Streptococcus pyogenes NCTC12069 SQF03893.1    
 NCTC12696_01300   Streptococcus pyogenes NCTC12696 SQF12883.1    
 NCTC12696_01102   Streptococcus pyogenes NCTC12696 SQF12699.1    
 NCTC12696_01531 (HylP)   Streptococcus pyogenes NCTC12696 SQF13111.1    
 NCTC12840_00523   Streptococcus pyogenes NCTC12840 SQF36052.1    
 NCTC12840_00765   Streptococcus pyogenes NCTC12840 SQF36483.1    
 NCTC13738_00863   Streptococcus pyogenes NCTC13738 SQG19575.1    
 NCTC13739_00681   Streptococcus pyogenes NCTC13739 SQH08627.1    
 NCTC13743_01037   Streptococcus pyogenes NCTC13743 SQG22800.1    
 NCTC13744_01109   Streptococcus pyogenes NCTC13744 SQG73318.1    
 NCTC13744_01447   Streptococcus pyogenes NCTC13744 SQG73639.1    
 NCTC13745_00583   Streptococcus pyogenes NCTC13745 SQH47662.1    
 NCTC13751_01255   Streptococcus pyogenes NCTC13751 SQH62852.1    
 NCTC4001_00660 (HylP)   Streptococcus pyogenes NCTC4001 SQF50225.1    
 NCTC4001_00483 (fragment)   Streptococcus pyogenes NCTC4001 SQF50049.1    
 NCTC4001_00482 (fragment)   Streptococcus pyogenes NCTC4001 SQF50048.1    
 NCTC5163_00807   Streptococcus pyogenes NCTC5163 SQE56134.1    
 NCTC5163_01047   Streptococcus pyogenes NCTC5163 SQE56631.1    
 NCTC5163_01287   Streptococcus pyogenes NCTC5163 SQE57170.1    
 NCTC5163_01116   Streptococcus pyogenes NCTC5163 SQE56772.1    
 NCTC5164_01287   Streptococcus pyogenes NCTC5164 SQE90839.1    
 NCTC5164_01116   Streptococcus pyogenes NCTC5164 SQE90669.1    
 NCTC5164_01047   Streptococcus pyogenes NCTC5164 SQE90600.1    
 NCTC5164_00807   Streptococcus pyogenes NCTC5164 SQE90364.1    
 NCTC8193_00587   Streptococcus pyogenes NCTC8193 VTP72388.1    
 NCTC8193_01686   Streptococcus pyogenes NCTC8193 VTP78827.1    
 NCTC8193_00734   Streptococcus pyogenes NCTC8193 VTP73271.1    
 NCTC8195_01159   Streptococcus pyogenes NCTC8195 SQF45658.1    
 NCTC8195_00718   Streptococcus pyogenes NCTC8195 SQF44848.1    
 NCTC8195_01539   Streptococcus pyogenes NCTC8195 SQF46440.1    
 NCTC8195_00622 (Hylp3)   Streptococcus pyogenes NCTC8195 SQF44680.1    
 NCTC8195_00263   Streptococcus pyogenes NCTC8195 SQF43881.1    
 ERS445054_01453   Streptococcus pyogenes NCTC8198 CKH05333.1    
 ERS445054_00613   Streptococcus pyogenes NCTC8198 CKG82209.1    
 ERS445054_01307 (HylP)   Streptococcus pyogenes NCTC8198 CKH01474.1    
 ERS445054_00899   Streptococcus pyogenes NCTC8198 CKG90139.1    
 NCTC8224_01063 (Hylp3)   Streptococcus pyogenes NCTC8224 SRX91036.1    
 NCTC8224_00721 (Hylp_2) (fragment)   Streptococcus pyogenes NCTC8224 SRX90699.1    
 NCTC8224_00577   Streptococcus pyogenes NCTC8224 SRX90557.1    
 NCTC8224_00720 (Hylp_1) (fragment)   Streptococcus pyogenes NCTC8224 SRX90698.1    
 NCTC8225_01005   Streptococcus pyogenes NCTC8225 SQE38596.1    
 NCTC8225_00555   Streptococcus pyogenes NCTC8225 SQE38162.1    
 NCTC8225_00286   Streptococcus pyogenes NCTC8225 SQE37903.1    
 NCTC8227_00965   Streptococcus pyogenes NCTC8227 SQG52357.1    
 NCTC8227_01293   Streptococcus pyogenes NCTC8227 SQG53079.1    
 NCTC8227_01143   Streptococcus pyogenes NCTC8227 SQG52623.1    
 NCTC8230_01627   Streptococcus pyogenes NCTC8230 SQF61520.1    
 NCTC8230_01119   Streptococcus pyogenes NCTC8230 SQF60518.1    
 NCTC8230_01291 (HylP)   Streptococcus pyogenes NCTC8230 SQF60840.1    
 NCTC8230_00272   Streptococcus pyogenes NCTC8230 SQF58692.1    
 NCTC8230_00863   Streptococcus pyogenes NCTC8230 SQF60040.1    
 NCTC8231_01010   Streptococcus pyogenes NCTC8231 SQF32808.1    
 NCTC8232_01491   Streptococcus pyogenes NCTC8232 VEE00365.1    
 NCTC8232_01074   Streptococcus pyogenes NCTC8232 VED99961.1    
 NCTC8232_01390   Streptococcus pyogenes NCTC8232 VEE00265.1    
 NCTC8232_00506   Streptococcus pyogenes NCTC8232 VED99414.1    
 NCTC8300_01412   Streptococcus pyogenes NCTC8300 SQF02499.1    
 NCTC8300_01000   Streptococcus pyogenes NCTC8300 SQF02100.1    
 NCTC8302_00564   Streptococcus pyogenes NCTC8302 VEF02257.1    
 NCTC8302_00957   Streptococcus pyogenes NCTC8302 VEF03016.1    
 NCTC8302_00713   Streptococcus pyogenes NCTC8302 VEF02553.1    
 NCTC8304_01007   Streptococcus pyogenes NCTC8304 SQG96868.1    
 NCTC8314_00747 (Hylp3)   Streptococcus pyogenes NCTC8314 SQE92822.1    
 NCTC8318_00820   Streptococcus pyogenes NCTC8318 VTR13015.1    
 NCTC8320_00629   Streptococcus pyogenes NCTC8320 SQG42580.1    
 NCTC8320_01067 (Hylp_1)   Streptococcus pyogenes NCTC8320 SQG43352.1    
 NCTC8320_01248 (Hylp_2)   Streptococcus pyogenes NCTC8320 SQG43724.1    
 NCTC8320_01517   Streptococcus pyogenes NCTC8320 SQG44323.1    
 NCTC8322_00564   Streptococcus pyogenes NCTC8322 SRX87147.1    
 NCTC8322_01260   Streptococcus pyogenes NCTC8322 SRX87813.1    
 NCTC8324_00424   Streptococcus pyogenes NCTC8324 SQF38000.1    
 NCTC8324_01001   Streptococcus pyogenes NCTC8324 SQF38584.1    
 NCTC8324_00823   Streptococcus pyogenes NCTC8324 SQF38407.1    
 NCTC8326_00684   Streptococcus pyogenes NCTC8326 SQF57170.1    
 NCTC8326_01331   Streptococcus pyogenes NCTC8326 SQF57802.1    
 NCTC8328_00784   Streptococcus pyogenes NCTC8328 SQF09662.1    
 NCTC8328_00395   Streptococcus pyogenes NCTC8328 SQF08894.1    
 NCTC8332_01047   Streptococcus pyogenes NCTC8332 SQF17824.1    
 NCTC8332_01287   Streptococcus pyogenes NCTC8332 SQF18063.1    
 NCTC8332_01116   Streptococcus pyogenes NCTC8332 SQF17893.1    
 NCTC8332_00807   Streptococcus pyogenes NCTC8332 SQF17588.1    
 SD89_06270   Streptococcus pyogenes NGAS322 AKZ50707.1    
 SD89_06945   Streptococcus pyogenes NGAS322 AKZ50836.1    
 SD89_05005   Streptococcus pyogenes NGAS322 AKZ50471.1    
 DK93_03885   Streptococcus pyogenes NGAS327 AKI38591.1    
 DK92_05065   Streptococcus pyogenes NGAS596 AKI37192.1    
 SD90_04815   Streptococcus pyogenes NGAS638 AKZ52250.1    
 DI45_04145   Streptococcus pyogenes NGAS743 AKI35205.1    
 DI45_03205   Streptococcus pyogenes NGAS743 AKI35031.1    
 C5P47_05700   Streptococcus pyogenes NGAS979 AWS23441.1    
 Spy49_0785   Streptococcus pyogenes NZ131 ACI61098.1    
 Spy49_1465c   Streptococcus pyogenes NZ131 ACI61737.1    
 EHF39_06555   Streptococcus pyogenes RLGH AZA33817.1    
 SP119_0555   Streptococcus pyogenes S119 VDC38840.1    
 D1F63_06555   Streptococcus pyogenes SASM4-Duke AYJ02721.1    
 D0Z58_03070   Streptococcus pyogenes SP1336 QBC34615.1    
 D0Z58_04360   Streptococcus pyogenes SP1336 QBC34853.1    
 SPs0763   Streptococcus pyogenes SSI-1 BAC63858.1
NP_802025.1		    
 SPs0927   Streptococcus pyogenes SSI-1 BAC64022.1
NP_802189.1		    
 SPs0447   Streptococcus pyogenes SSI-1 BAC63542.1
NP_801709.1		    
 SPs1127 (fragment)   Streptococcus pyogenes SSI-1 BAC64222.1
NP_802389.1		    
 SPs0648   Streptococcus pyogenes SSI-1 BAC63743.1
NP_801910.1		    
 B4W66_05875   Streptococcus pyogenes STAB090229 ASQ21424.1    
 EZY40_02900   Streptococcus pyogenes STAB09023 QGU90350.1    
 EZ612_02900   Streptococcus pyogenes STAB10048 QGU91958.1    
 B5D85_06210   Streptococcus pyogenes STAB120304 ASQ23235.1    
 AXK13_03295   Streptococcus pyogenes STAB13021 AND04600.1    
 AXK13_07410   Streptococcus pyogenes STAB13021 AND05369.1    
 AYM92_06065   Streptococcus pyogenes STAB14018 ARV01471.1    
 STAB902_02535   Streptococcus pyogenes STAB902 AIG46749.1
AIG47403.1		    
 STAB902_04220   Streptococcus pyogenes STAB902 AIG47045.1    
 STAB902_03630   Streptococcus pyogenes STAB902 AIG46933.1
AIG47203.1		    
 SpyM50524   Streptococcus pyogenes str. Manfredo CAM29863.1    
 SpyM50680   Streptococcus pyogenes str. Manfredo CAM30013.1    
 SpyM51031   Streptococcus pyogenes str. Manfredo CAM30356.1    
 SpyM51271   Streptococcus pyogenes str. Manfredo CAM30596.1    
 D8S76_06805   Streptococcus pyogenes TSPY155 QAX76550.1    
 EB817_03660   Streptococcus pyogenes TSPY165 QAX70924.1    
 EB818_03870   Streptococcus pyogenes TSPY208 QAX72671.1    
 EB818_07705   Streptococcus pyogenes TSPY208 QAX73349.1    
 EB816_05355   Streptococcus pyogenes TSPY453 QAX69383.1    
 D8S77_03465   Streptococcus pyogenes TSPY556 QAX74246.1    
 SP4011_11550 (fragment)   Streptococcus sp. SP4011 BDT64738.1    
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BV0002_038   Streptococcus phage BV-0002 WDS50820.1    
 Javan177_0009   Streptococcus phage Javan177 QBX15195.1    
 Javan183_0045   Streptococcus phage Javan183 QBX15374.1    
 Javan184_0046   Streptococcus phage Javan184 QBX24365.1    
 Javan185_0009   Streptococcus phage Javan185 QBX15391.1    
 Javan186_0046   Streptococcus phage Javan186 QBX24419.1    
 Javan187_0001   Streptococcus phage Javan187 QBX15437.1    
 Javan188_0009   Streptococcus phage Javan188 QBX24436.1    
 Javan189_0009   Streptococcus phage Javan189 QBX15487.1    
 Javan196_0009   Streptococcus phage Javan196 QBX24600.1    
 Javan446_0013   Streptococcus phage Javan446 QBX28227.1    
 Javan447_0011 (fragment)   Streptococcus phage Javan447 QBX18817.1    
 Javan448_0010   Streptococcus phage Javan448 QBX28292.1    
 Javan450_0008   Streptococcus phage Javan450 QBX28328.1    
 Javan451_0008   Streptococcus phage Javan451 QBX18871.1    
 Javan452_0056   Streptococcus phage Javan452 QBX28427.1    
 Javan456_0055   Streptococcus phage Javan456 QBX28549.1    
 Javan457_0008   Streptococcus phage Javan457 QBX18923.1    
 Javan459_0046   Streptococcus phage Javan459 QBX19005.1    
 Javan460_0042   Streptococcus phage Javan460 QBX28707.1    
 Javan464_0013   Streptococcus phage Javan464 QBX28728.1    
 Javan465_0007   Streptococcus phage Javan465 QBX19020.1    
 Javan467_0045   Streptococcus phage Javan467 QBX19106.1    
 Javan470_0046   Streptococcus phage Javan470 QBX28828.1    
 Javan472_0044   Streptococcus phage Javan472 QBX28881.1    
 Javan474_0009   Streptococcus phage Javan474 QBX28899.1    
 Javan476_0047   Streptococcus phage Javan476 QBX28998.1    
 Javan477_0047   Streptococcus phage Javan477 QBX19273.1    
 Javan481_0042   Streptococcus phage Javan481 QBX19323.1    
 Javan483_0010   Streptococcus phage Javan483 QBX19342.1    
 Javan484_0012   Streptococcus phage Javan484 QBX29146.1    
 Javan485_0010   Streptococcus phage Javan485 QBX19400.1    
 Javan486_0012   Streptococcus phage Javan486 QBX29217.1    
 Javan487_0010   Streptococcus phage Javan487 QBX19456.1    
 Javan488_0041   Streptococcus phage Javan488 QBX29306.1    
 Javan489_0053   Streptococcus phage Javan489 QBX19549.1    
 Javan491_0045   Streptococcus phage Javan491 QBX19637.1    
 Javan492_0049 (fragment)   Streptococcus phage Javan492 QBX29363.1    
 Javan493_0009 (fragment)   Streptococcus phage Javan493 QBX19656.1    
 Javan494_0009 (fragment)   Streptococcus phage Javan494 QBX29383.1    
 Javan496_0012 (fragment)   Streptococcus phage Javan496 QBX29437.1    
 Javan496_0013 (fragment)   Streptococcus phage Javan496 QBX29438.1    
 Javan497_0041   Streptococcus phage Javan497 QBX19747.1    
 Javan498_0010   Streptococcus phage Javan498 QBX29484.1    
 Javan501_0056   Streptococcus phage Javan501 QBX19914.1    
 Javan502_0010   Streptococcus phage Javan502 QBX29532.1    
 Javan507_0047   Streptococcus phage Javan507 QBX20078.1    
 Javan508_0010 (fragment)   Streptococcus phage Javan508 QBX29633.1    
 Javan508_0011 (fragment)   Streptococcus phage Javan508 QBX29634.1    
 Javan509_0008   Streptococcus phage Javan509 QBX20098.1    
 Javan511_0012   Streptococcus phage Javan511 QBX20188.1    
 Javan512_0012   Streptococcus phage Javan512 QBX29752.1    
 Javan520_0010   Streptococcus phage Javan520 QBX29998.1    
 Javan521_0049   Streptococcus phage Javan521 QBX20461.1    
 Javan522_0052   Streptococcus phage Javan522 QBX30097.1    
 Javan523_0011   Streptococcus phage Javan523 QBX20480.1    
 Javan525_0046   Streptococcus phage Javan525 QBX20576.1    
 Javan526_0055   Streptococcus phage Javan526 QBX30214.1    
 Javan527_0011   Streptococcus phage Javan527 QBX20595.1    
 Javan528_0044   Streptococcus phage Javan528 QBX30266.1    
 Javan530_0050   Streptococcus phage Javan530 QBX30322.1    
 Javan531_0042   Streptococcus phage Javan531 QBX20777.1    
 Javan532_0011 (fragment)   Streptococcus phage Javan532 QBX30345.1    
 Javan532_0010 (fragment)   Streptococcus phage Javan532 QBX30344.1    
 MissB1_0012 (fragment)   Streptococcus phage MissB1 UJD17837.1    
 MissC_0063 (fragment)   Streptococcus phage MissC UJD17956.1    
 MissE1_0012 (fragment)   Streptococcus phage MissE1 UJD18031.1    
 MissF_0012 (fragment)   Streptococcus phage MissF UJQ44939.1    
 MissG1_0008 (fragment)   Streptococcus phage MissG1 UJH95058.1    
 hylauronidase   Streptococcus phage P9 ABL61072.1    
 hyaluronidase   Streptococcus phage phiNIH1.1 AAL15086.1
NP_438157.1		    
 hyaluronate lyase (HylP1;HylP) 4.2.2.1 Streptococcus pyogenes phage H4489A AAA98101.1 P15316 6WV2[A,B,C]
6WWX[A,B,C]
6WXA[A,B,C]
6X3M[A,B,C,D,E,F,G,H,I]
 SEA_ALONE_86   Streptomyces phage Alone3 WPH58274.1    
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