Polysaccharide Lyase Family 15

Activities in Family	Exo-heparin lyase (reducing-end specific) (EC 4.2.2.-); Oligoalginate lyase / exo-alginate lyase (EC 4.2.2.26); Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3);
Mechanism	b-elimination
3D Structure Status	( α / α ) ₆ toroid + anti-parallel β-sheet
External resources	CAZypedia;
Statistics	GenBank accession (514); Uniprot accession (7); PDB accession (4); 3D entries (2); cryst (0)

Bacteria

Protein Name

EC#

Organism

GenBank

Uniprot

PDB/3D

Carbohydrate Ligands

Resolution (Å)

Subf

exotype alginate lyase (Atu3025)

AAL43841.1
AAK90358.1
NP_357573.1
NP_533525.1

3A0O[A,B]		2.11
3AFL[A]	β-D-4-deoxy-ManpA-(1-4)-α-L-GulpA-(1-4)-α-L-GulpA	2.99

reducing-end specific exo-heparin lyase (BIexoHep; BACINT_00178)

WP_007659809.1
EDV07780.1

6LJA[A]	α-L-4-deoxy-IdopA2SO3-(1-4)-α-D-GlcpNSO36SO3	1.98
6LJL[A]	β-D-4-deoxy-GlcpA-(1-4)-α-D-GlcpNSO36SO3-(1-4)-α-L-IdopA2SO3-(1-4)-α-D-GlcpNSO36SO3	1.73