Activities in Family	β-galactoside α-2,6-sialyltransferase (EC 2.4.99.1); β-galactoside α-2,3-sialyltransferase (EC 2.4.99.4)
Mechanism	Inverting
3D Structure Status	GT-B
Note	created from reading Yamamoto, Nakashizuka and Terada (1998) J Biochem (Tokyo) 123:94-100
Commercial Enzyme Provider(s)	CHEMILY; PROZOMIX;
Statistics	GenBank accession (247); Uniprot accession (12); PDB accession (24); 3D entries (6); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
CMP-Neu5Ac α-2,3-sialyltransferase (PdST) (has also CMP-Neu5Ac hydrolase activity)	2.4.99.4	Pasteurella dagmatis DSM 22969	AFY98851.1	K9UUI6	4V2U[A] 2.71 4V38[A] 1.96 4V39[A] 2.60 4V3B[A] 2.18 4V3C[A] 1.84
CMP-NeuAc : α-2,3/2,6-sialyltransferase 1 / sialidase (St1;PmST1)	2.4.99.1 2.4.99.4	Pasteurella multocida ATCC 15742 / P-1059	AAY89061.1	Q15KI8	2IHJ[A] 2.00 2IHK[A] 1.90 2IHZ[A] β-D-Galp-(1-4)-α-D-Glcp 2.00 2II6[A] 1.75 2IIB[A] 2.20 2IIQ[A,B] 2.30 2ILV[A] β-D-Galp-(1-4)-α-D-Glcp 2.27 3S44[A] 1.45
CMP-Neu5Ac: [galactosyl oligosaccharide] α-2,3/6-sialyltransferase 1 (St1;PmST1;PM0188)	2.4.99.1 2.4.99.4	Pasteurella multocida subsp. multocida str. Pm70	AAK02272.1 NP_245125.1	Q15KI8 Q9CP67	2C83[A] 1.9 2C84[A] 2.31 2EX0[A,B] 1.65 2EX1[A] 2.00 2IY7[A] 1.85 2IY8[A] β-D-Galp-(1-4)-β-D-Glcp 2.50
CMP-NeuAc: β-galactoside α-2,6-sialyltransferase (Bst;Pd2,6ST)	2.4.99.1	Photobacterium damselae JT0160	BAA25316.1	O66375	4R83[A,B,C,D] 1.93 4R84[A,B,C,D] 1.70 4R9V[A] 2.30
CMP-NeuAc: a-/β-galactoside α-2,3-sialyltransferase	2.4.99.4	Photobacterium phosphoreum JT-ISH-467	BAF63530.1	A5LHX0	2ZWI[A,B] 2.01
CMP-NeuAc: β-galactoside α-2,6-sialyltransferase (pst6-224;Psp2,6ST)	2.4.99.1	Photobacterium sp. JT-ISH-224	BAF92026.1	A8QYL1	2Z4T[A] β-D-Galp-(1-4)-α-D-Glcp 2.50
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