GlycosylTransferase Family 80

Activities in Familyβ-galactoside α-2,6-sialyltransferase (EC 2.4.99.1); β-galactoside α-2,3-sialyltransferase (EC 2.4.99.4)
Mechanism Inverting
3D Structure StatusGT-B
Notecreated from reading Yamamoto, Nakashizuka and Terada (1998) J Biochem (Tokyo) 123:94-100
Commercial Enzyme Provider(s)CHEMILY; PROZOMIX;
Statistics GenBank accession (77); Uniprot accession (11); PDB accession (24); 3D entries (6); cryst (0)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CMP-Neu5Ac: α-2,3-sialyltransferase (BtST1;WQG_5820) 2.4.99.4 Bibersteinia trehalosi USDA-ARS-USMARC-192 AGH37861.1    
 CMP-Neu5Ac: LacMU α-2,3-sialyltransferase (HD0053) 2.4.99.4 Haemophilus ducreyi 35000HP AAP95068.1
NP_872679.1
Q7VPL1  
 CMP-Neu5Ac α-2,3-sialyltransferase (PdST) (has also CMP-Neu5Ac hydrolase activity) 2.4.99.4 Pasteurella dagmatis DSM 22969 AFY98851.1   4V2U[A]
4V38[A]
4V39[A]
4V3B[A]
4V3C[A]
 CMP-NeuAc : α-2,3/2,6-sialyltransferase 1 / sialidase (St1;PmST1) 2.4.99.1
2.4.99.4
3.2.1.18
Pasteurella multocida ATCC 15742 / P-1059 AAY89061.1 Q15KI8 2IHJ[A]
2IHK[A]
2IHZ[A]
2II6[A]
2IIB[A]
2IIQ[A,B]
2ILV[A]
3S44[A]
 CMP-Neu5Ac: [galactosyl oligosaccharide] α-2,3/6-sialyltransferase 1 (St1;PmST1;PM0188) 2.4.99.1
2.4.99.4
Pasteurella multocida subsp. multocida str. Pm70 AAK02272.1
NP_245125.1
Q9CP67 2C83[A]
2C84[A]
2EX0[A,B]
2EX1[A]
2IIB[A]
2IY7[A]
2IY8[A,A]
 CMP-NeuAc: β-galactoside α-2,6-sialyltransferase (Bst;Pd2,6ST) 2.4.99.1 Photobacterium damselae JT0160 BAA25316.1 O66375 4R83[A,B,C,D]
4R84[A,B,C,D]
4R9V[A]
 α-2,6-sialyltransferase / α-2,6-linkage-specific neuraminidase (Plst6) 2.4.99.1
3.2.1.-
Photobacterium leiognathi JT-SHIZ-119 BAI49484.1 D0VYB7  
 CMP-NeuAc: β-galactoside α-2,6-sialyltransferase (Plst6) 2.4.99.1 Photobacterium leiognathi JT-SHIZ-145 BAF91416.1 A8R0T5  
 CMP-NeuAc: a-/β-galactoside α-2,3-sialyltransferase 2.4.99.4 Photobacterium phosphoreum JT-ISH-467 BAF63530.1 A5LHX0 2ZWI[A,B]
 CMP-NeuAc: a-/β-galactoside α-2,3-sialyltransferase (pst3-224) 2.4.99.4 Photobacterium sp. JT-ISH-224 BAF92025.1 A8QYL0  
 CMP-NeuAc: β-galactoside α-2,6-sialyltransferase (pst6-224;Psp2,6ST) 2.4.99.1 Photobacterium sp. JT-ISH-224 BAF92026.1 A8QYL1 2Z4T[A]
 CMP-NeuAc: a/β-galactoside α-2,3-sialyltransferase (2,3st) 2.4.99.4 Vibrio sp. JT-FAJ-16 BAF91160.1 A8R0Y0  
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