GlycosylTransferase Family 66

Activities in Familydolichyl-diphosphooligosaccharide—protein glycotransferase (EC 2.4.99.18); undecaprenyl-diphosphooligosaccharide—protein glycotransferase (EC 2.4.99.19)
Mechanism Inverting
3D Structure StatusGT-C
NoteThese enzymes utilize a lipid-diphospho-oligosaccharide as the donor
External resourcesGlymap;
Statistics GenBank accession (1234); Uniprot accession (267); PDB accession (13); 3D entries (8); cryst (0)
All (1091) Archaea (487) Bacteria (261) Eukaryota (341) unclassified (2) Structure (8) Characterized (17)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 oligosaccharyltransferase (AglB-S1;AfAglB-S1;AF0329;AF_0329) 2.4.99.18 Archaeoglobus fulgidus DSM 4304 AAB90907.1
NP_069165.1
O29918 3VGP[A]
 oligosaccharyltransferase (AglB-L;AfAglB-L;AF_0380) 2.4.99.18 Archaeoglobus fulgidus DSM 4304 AAB90856.1 O29867 3WAI[A]
3WAJ[A]
3WAK[A]
5GMY[A]
 oligosaccharyltransferase (AglB;Stt3) 2.4.99.18 Haloferax volcanii WR536 (H53) CAP58184.1 A9JPF0  
 oligosaccharyltransferase (AglB;Stt3;Mv1749;MVO1749) 2.4.99.18 Methanococcus voltae PS ABD17750.1    
 oligosaccharyltransferase (AglB;Stt3;PF0156) 2.4.99.18 Pyrococcus furiosus DSM 3638 AAL80280.1
NP_577885.1
Q8U4D2 2ZAG[A,B,C,D]
2ZAI[A,B,C,D]
5AZA[A]
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Undecaprenyl-diphosphooligosaccharide--protein glycotransferase (PglB;WlaF) 2.4.99.19 Campylobacter jejuni subsp. jejuni 81-176 AAK97438.1
AAD51383.1
EAQ72203.1
A1W0B2
Q93DP5
Q9S4V7
 
 Undecaprenyl-diphosphooligosaccharide--protein glycotransferase (PglB;WlaF;Cj1126c) 2.4.99.19 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 CAB73381.1
AAD09293.1
CAL35243.1
NP_282274.1
Q0P9C8
Q9ZAC7
 
 Undecaprenyl-diphosphooligosaccharide--protein glycotransferase (PglB;Cla_1253) 2.4.99.19 Campylobacter lari RM2100 ACM64573.1 B9KDD4 3RCE[A]
 oligosaccharyltransferase (PglB1) 2.4.99.19 Helicobacter pullorum NCTC 12824 ADM36003.1 E1B265  
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 oligosaccharyltransferase subunit STT3 (Stt3A;B5;ITM1) 2.4.99.18 Homo sapiens NP_689926.1
AAB05994.1
AAH20965.1
AAH48348.1
AAH48348.2
AAL77539.1
AAP35764.1
ACM84938.1
BAF82729.1
BAG58686.1
CAH05569.1
CAH05570.1
CAH05571.1
CAH05572.1
P46977
Q86XU9
Q8TE35
 
 oligosaccharyltransferase STT3 subunit (YGL022w;Stt3;RHK2) 2.4.99.18 Saccharomyces cerevisiae S288c BAA06079.1
ABC17138.1
CAA96722.1
NP_011493.1
P39007  
 oligosaccharyltransferase (Stt3;SPBC1271.02) 2.4.99.18 Schizosaccharomyces pombe 972h- CAA22192.1
BAA76479.1
NP_595148.1
O94335
O94335
 
 oligosaccharyltransferase (Stt3) 2.4.99.18 Toxoplasma gondii RH TACHYZOITES CAB38944.1 O97353  
 oligosaccharyltransferase (Stt3C;Tb927.5.910) 2.4.99.18 Trypanosoma brucei AAX70183.1
AAX70186.1
Q57W36  
 oligosaccharyltransferase (Stt3B;Tb927.5.900) 2.4.99.18 Trypanosoma brucei AAX70184.1 Q57W35  
 oligosaccharyltransferase (Stt3A;Tb927.5.890) 2.4.99.18 Trypanosoma brucei AAX70185.1 Q57W34  
 oligosaccharyltransferase (Stt3;Tc00.1047053505163.80) 2.4.99.18 Trypanosoma cruzi CL BRENER EAN86688.1 Q4D2C9  
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