| Activities in Family | Dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase (EC 2.4.1.119); Dolichyl-diphosphooligosaccharide—protein glycotransferase (EC 2.4.99.18); Undecaprenyl-diphosphooligosaccharide--protein glycotransferase (EC 2.4.99.19); |
|---|---|
| Mechanism | Inverting |
| 3D Structure Status | GT-C |
| Note | These enzymes utilize a lipid-diphospho-oligosaccharide as the donor |
| External resources | Glymap; |
| Statistics | GenBank accession (2665); Uniprot accession (28); PDB accession (47); 3D entries (12); cryst (0) |
| Archaea | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| oligosaccharyltransferase (AglB-S1;AfAglB-S1;AF0329;AF_0329) | 2.4.99.18 | Archaeoglobus fulgidus DSM 4304 | AAB90907.1 NP_069165.1 |
O29918 | 3VGP[A] | ||
| oligosaccharyltransferase (AglB-L;AfAglB-L;AF_0380) | 2.4.99.18 | Archaeoglobus fulgidus DSM 4304 | AAB90856.1 | O29867 | 3WAI[A] 3WAJ[A] 3WAK[A] 5GMY[A] 7E9S[A] |
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| oligosaccharyltransferase (AglB;Stt3) | 2.4.99.18 | Haloferax volcanii WR536 (H53) | CAP58184.1 | A9JPF0 D4GYH4 |
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| oligosaccharyltransferase (AglB;Stt3;Mv1749;MVO1749) | 2.4.99.18 | Methanococcus voltae PS | ABD17750.1 | Q2EMT4 | |||
| oligosaccharyltransferase (AglB;Stt3;PF0156) | 2.4.99.18 | pubmed |
Pyrococcus furiosus DSM 3638 | AAL80280.1 NP_577885.1 |
I6V0B8 Q8U4D2 |
2ZAG[A,B,C,D] 2ZAI[A,B,C,D] 5AZA[A] |
|
| oligosaccharyltransferase (AglB-L;PhAglB-L;PH0242) | 2.4.1.119 | pubmed |
Pyrococcus horikoshii OT3 | BAA29314.1 NP_142238.1 |
O74088 | 3VU1[A,B] | |
| Bacteria | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| Undecaprenyl-diphosphooligosaccharide--protein glycotransferase (PglB;WlaF) | 2.4.99.19 | Campylobacter jejuni subsp. jejuni 81-176 | AAK97438.1 AAD51383.1 EAQ72203.1 |
A0A0H3P9U9 A1W0B2 Q93DP5 Q9S4V7 |
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| Undecaprenyl-diphosphooligosaccharide--protein glycotransferase (PglB;WlaF;Cj1126c) | 2.4.99.19 | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 | CAB73381.1 AAD09293.1 CAL35243.1 NP_282274.1 |
Q0P9C8 Q9ZAC7 |
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| Undecaprenyl-diphosphooligosaccharide--protein glycotransferase (PglB;Cla_1253) | 2.4.99.19 | Campylobacter lari RM2100 | ACM64573.1 | B9KDD4 | 3RCE[A] 5OGL[A] 6GXC[A] |
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| oligosaccharyltransferase (PglB1) | 2.4.99.19 | Helicobacter pullorum NCTC 12824 | ADM36003.1 | E1B265 | |||
| Eukaryota | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| dolichyl-diphosphooligosaccharide: protein glycotransferase / oligosaccharyltransferase subunit STT3 (OST-A; Stt3A; B5; ITM1) | 2.4.99.18 | pubmed |
Homo sapiens | NP_689926.1 AAB05994.1 AAH20965.1 AAH48348.1 AAH48348.2 AAL77539.1 AAP35764.1 ACM84938.1 BAF82729.1 BAG58686.1 CAH05569.1 CAH05570.1 CAH05571.1 CAH05572.1 |
P46977 Q86XU9 Q8TE35 |
6S7O[A] 8B6L[I] 8PN9[A] |
|
| dolichyl-diphosphooligosaccharide: protein glycotransferase / oligosaccharyltransferase subunit STT3B (SIMP; OST-B) | 2.4.99.18 | pubmed |
Homo sapiens | AAL71884.1 AAH15880.1 ABA83583.1 ABA84110.1 BAB55370.1 BAC11076.1 BAC11581.1 CAC39710.1 CAE48447.1 CAE91783.1 CAF00240.1 CAF85831.1 CAI72081.1 NP_849193.1 |
Q8TCJ2 | 6S7T[A] | |
| oligosaccharyltransferase STT3 subunit (YGL022w;Stt3;RHK2) | 2.4.99.18 | pubmed |
Saccharomyces cerevisiae S288c | BAA06079.1 ABC17138.1 CAA96722.1 NP_011493.1 |
P39007 | 2LGZ[A] 6C26[A] 6EZN[F] 7OCI[F] 8AGB[A] 8AGC[A] 8AGE[A] |
|
| oligosaccharyltransferase (Stt3;SPBC1271.02) | 2.4.99.18 | Schizosaccharomyces pombe 972h- | CAA22192.1 BAA76479.1 CAK8728358.1 NP_595148.1 |
O94335 O94335 |
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| oligosaccharyltransferase (Stt3) | 2.4.99.18 | Toxoplasma gondii RH TACHYZOITES | CAB38944.1 | O97353 | |||
| oligosaccharyltransferase (Stt3C;Tb927.5.910) | 2.4.99.18 | Trypanosoma brucei brucei TREU927 | AAX70183.1 AAX70186.1 |
Q57W33 Q57W36 |
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| oligosaccharyltransferase (Stt3B;Tb927.5.900) | 2.4.99.18 | Trypanosoma brucei brucei TREU927 | AAX70184.1 | Q57W35 | |||
| oligosaccharyltransferase (Stt3A;Tb927.5.890) | 2.4.99.18 | Trypanosoma brucei brucei TREU927 | AAX70185.1 | Q57W34 | |||
| oligosaccharyltransferase (Stt3;Tc00.1047053505163.80) | 2.4.99.18 | Trypanosoma cruzi CL BRENER | EAN86688.1 | Q4D2C9 | |||
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