GlycosylTransferase Family 2

Activities in FamilyGDP-Man α-mannosyltransferase (EC 2.4.1.-);
GDP-Man: β-mannosyltransferase (EC 2.4.1.-);
GDP-β-L-Fuc : D-Glc-β-1,3-D-GalNAc-PP-Ph α-1,4-L-fucosyltransferase (EC 2.4.1.-);
Hexosyltransferases (EC 2.4.1.-);
LOS β-1,4-glucosyltransferase (EC 2.4.1.-);
N-acetylgalactosaminyltransferase (EC 2.4.1.-);
N-acetylglucosaminyltransferase (EC 2.4.1.-);
UDP-Gal: α-GlcNAc-PP-lipid β-1,3-galactosyltransferase (EC 2.4.1.-);
UDP-Gal:queuosine β-galactosyltransferase (EC 2.4.1.-);
UDP-GalNAc: β-1,3-N-acetylgalactosaminyltrasferase (EC 2.4.1.-);
UDP-GalNAc: undecaprenyl-P β-N-acetylgalactosaminyltransferase (EC 2.4.1.-);
UDP-Glc : GalNAc-PP-Und β-1,3-glucosyltransferase (EC 2.4.1.-);
UDP-Glc: β-1,6-glucan synthase (EC 2.4.1.-);
UDP-Glc: β-glucosyltransferase (EC 2.4.1.-);
UDP-Glc: bactoprenol β-glucosyltransferase (EC 2.4.1.-);
UDP-Glc: teichoic acid β-glucosyltransferase (EC 2.4.1.-);
UDP-GlcA: LOS β-glucuronyltransferase (EC 2.4.1.-);
UDP-GlcA: [hyaluronan] β-1,4-glucuronyltransferase (EC 2.4.1.-);
UDP-GlcNAc: [hyaluronan] β-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.-);
[inverting] UDP-Glc: glycocin S-β-glucosyltransferase (EC 2.4.1.-);
[inverting] UDP-Glc: protein O-β-glucosyltransferase (EC 2.4.1.-);
[inverting] UDP-GlcNAc: [chitooligosaccharide] β-1,4-N-acetylglucosaminyltransferase (EC 2.4.1.-);
[inverting] UDP-GlcNAc: teichoic acid β-N-acetylglucosaminyltransferase (EC 2.4.1.-);
[inverting] β-1,6-glucosyltransferase (EC 2.4.1.-);
[inverting] dTDP-spectinose: β-spectinosyltransferase (EC 2.4.1.-);
[inverting] glucomannan synthase (EC 2.4.1.-);
α-1,3-rhamnosyltransferase (unspecified donor) (EC 2.4.1.-);
α-1,4-L-fucosyltransferase (EC 2.4.1.-);
α-1,6-L-fucosyltransferase (EC 2.4.1.-);
Alternating β-1,3/4-N-acetylmannan synthase (EC 2.4.1.-);
Arabinoglucan synthase (EC 2.4.1.-);
β-1,3-1,4-glucan synthase (EC 2.4.1.-);
β-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.-);
β-1,3-galactosyltransferase (EC 2.4.1.-);
β-1,3-glucosyltransferase (EC 2.4.1.-);
β-1,4-galactosyltransferase (EC 2.4.1.-);
β-1,4-glucosyltransferase (EC 2.4.1.-);
Chlorobactene β-glucosyltransferase (EC 2.4.1.-);
DTDP-L-Rha: α-L-rhamnosyltransferase (EC 2.4.1.-);
Poly-β-1,6-N-acetylglucosamine synthase (EC 2.4.1.-);
Staphyloxanthin β-glucosyltransferase (EC 2.4.1.-);
Xyloglucan β-1,4-glucan synthase (EC 2.4.1.-);
UDP-Glc: dolichyl-phosphate β-glucosyltransferase (EC 2.4.1.117);
UDP-Glc: β-1,4-glucan synthase / cellulose synthase (UDP-forming) (EC 2.4.1.12);
UDP-Glc: 1,2-diacylglycerol 3-glucosyltransferase (EC 2.4.1.157);
Chitin transglycosylase (EC 2.4.1.16);
UDP-GlcA: β-glucuronosyltransferase (EC 2.4.1.17);
UDP-GalNAc: β-1,3-glucuronyl-N-acetylgalactosaminyl-proteoglycan β-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.175);
β-Man-P-decaprenol: α-1,6-mannooligosaccharide α-1,6-mannosyltransferase (EC 2.4.1.199);
Hyaluronan synthase (EC 2.4.1.212);
UDP-GlcA: N-acetylglucosaminyl-proteoglycan β-1,4-glucuronosyltransferase (EC 2.4.1.225);
UDP-GlcA: N-acetylgalactosaminyl-proteoglycan β-1,3-glucuronosyltransferase (EC 2.4.1.226);
UDP-Galf: rhamnopyranosyl-N-acetylglucosaminyl-PP-decaprenol β-1,4/1,5-galactofuranosyltransferase (EC 2.4.1.287);
UDP-Galf: [galactan] Galf-Galf-Rhα-GlcNAc-PP-decaprenol β-1,5/1,6-galactofuranosyltransferase (EC 2.4.1.288);
DTDP-L-Rha: N-acetylglucosaminyl-PP-decaprenol α-1,3-L-rhamnosyltransferase (EC 2.4.1.289);
β-1,3-glucosyltransferase (EC 2.4.1.305);
[inverting] GDP-Man: β-mannan β-1,4-mannosyltransferase / glucomannan synthase (EC 2.4.1.32);
Mannuronan synthase (EC 2.4.1.33);
UDP-Glc: β-1,3-glucan synthase / callose synthase (EC 2.4.1.34);
GDP-Man: Dol-P β-mannosyltransferase (EC 2.4.1.83);
UDP-L-Arap-4N-formyl : undecaprenyl-P α-L-4N-formylarabinosyltransferase (EC 2.4.2.-);
Mechanism Inverting
3D Structure StatusGT-A
NoteDistant similarity to families GT12, GT21, GT27, GT55, GT81 etc.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (369404); Uniprot accession (389); PDB accession (82); 3D entries (27); cryst (0)
| 1 | ... | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | ... | 60 |
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 THER333_0604   Thermococcus nautili 33-3 CAI1492439.1    
 THER333_1757   Thermococcus nautili 33-3 CAI1493592.1    
 THER333_0602   Thermococcus nautili 33-3 CAI1492437.1    
 TON_1366   Thermococcus onnurineus NA1 ACJ16856.1    
 TON_1918   Thermococcus onnurineus NA1 ACJ17409.1    
 TON_1695   Thermococcus onnurineus NA1 ACJ17185.1    
 TON_0615   Thermococcus onnurineus NA1 ACJ16102.1    
 TON_0719   Thermococcus onnurineus NA1 ACJ16207.1    
 TON_1822   Thermococcus onnurineus NA1 ACJ17312.1    
 TON_1975 (fragment)   Thermococcus onnurineus NA1 ACJ17344.1    
 TON_1861   Thermococcus onnurineus NA1 ACJ17352.1    
 TON_1862   Thermococcus onnurineus NA1 ACJ17353.1    
 A3L08_03120   Thermococcus pacificus P-4 ASJ06394.1    
 A3L08_07030   Thermococcus pacificus P-4 ASJ07092.1    
 A3L08_03115 (fragment)   Thermococcus pacificus P-4 ASJ06393.1    
 A3L08_07515   Thermococcus pacificus P-4 ASJ07177.1    
 A3L08_03110   Thermococcus pacificus P-4 ASJ06392.1    
 A3L08_08310   Thermococcus pacificus P-4 ASJ07323.1    
 A3L08_03440   Thermococcus pacificus P-4 ASJ06448.1    
 A3L08_00820   Thermococcus pacificus P-4 ASJ05976.1    
 A3L08_02300   Thermococcus pacificus P-4 ASJ06241.1    
 TES1_1039   Thermococcus paralvinellae ES1 AHF80423.1    
 TES1_1885   Thermococcus paralvinellae ES1 AHF81260.1    
 TES1_1735   Thermococcus paralvinellae ES1 AHF81110.1    
 TES1_0555   Thermococcus paralvinellae ES1 AHF79945.1    
 TES1_0577   Thermococcus paralvinellae ES1 AHF79967.1    
 TES1_2036   Thermococcus paralvinellae ES1 AHF81411.1    
 A0127_06535   Thermococcus peptonophilus OG-1 AMQ18853.1    
 A0127_06620   Thermococcus peptonophilus OG-1 AMQ19534.1    
 A0127_06525   Thermococcus peptonophilus OG-1 AMQ19533.1    
 A0127_06505   Thermococcus peptonophilus OG-1 AMQ18849.1    
 A0127_07400   Thermococcus peptonophilus OG-1 AMQ19006.1    
 A0127_06610   Thermococcus peptonophilus OG-1 AMQ18868.1    
 A0127_04095   Thermococcus peptonophilus OG-1 AMQ18410.1    
 A0127_02485   Thermococcus peptonophilus OG-1 AMQ18114.1    
 A0127_06635   Thermococcus peptonophilus OG-1 AMQ18871.1    
 A0127_09895   Thermococcus peptonophilus OG-1 AMQ19451.1    
 A0127_01260   Thermococcus peptonophilus OG-1 AMQ17895.1    
 A7C91_05640   Thermococcus piezophilus CDGS ANF23598.1    
 A7C91_02525   Thermococcus piezophilus CDGS ANF22184.1    
 A7C91_09735 (fragment)   Thermococcus piezophilus CDGS ANF23411.1    
 A7C91_03580   Thermococcus piezophilus CDGS ANF22357.1    
 A7C91_05195   Thermococcus piezophilus CDGS ANF22632.1    
 A7C91_09115   Thermococcus piezophilus CDGS ANF23312.1    
 A7C91_05170   Thermococcus piezophilus CDGS ANF22627.1    
 A3L09_01795   Thermococcus profundus DT 5432 ASJ02086.1    
 A3L09_01815   Thermococcus profundus DT 5432 ASJ02090.1    
 A3L09_05450   Thermococcus profundus DT 5432 ASJ03735.1    
 A3L09_01810   Thermococcus profundus DT 5432 ASJ02089.1    
 A3L09_10290   Thermococcus profundus DT 5432 ASJ03619.1    
 A3L09_04830   Thermococcus profundus DT 5432 ASJ02631.1    
 A3L09_10160   Thermococcus profundus DT 5432 ASJ03594.1    
 A3L09_10155   Thermococcus profundus DT 5432 ASJ03593.1    
 A3L09_08145   Thermococcus profundus DT 5432 ASJ03225.1    
 A3L10_09600   Thermococcus radiotolerans EJ2 ASJ15370.1    
 A3L10_00710   Thermococcus radiotolerans EJ2 ASJ13718.1    
 A3L10_08840   Thermococcus radiotolerans EJ2 ASJ15228.1    
 A3L10_10000   Thermococcus radiotolerans EJ2 ASJ15568.1    
 A3L10_07030   Thermococcus radiotolerans EJ2 ASJ14901.1    
 A3L10_02770   Thermococcus radiotolerans EJ2 ASJ14107.1    
 A3L10_02195   Thermococcus radiotolerans EJ2 ASJ13998.1    
 TSIB_0005   Thermococcus sibiricus MM 739 ACS89076.1    
 TSIB_0006   Thermococcus sibiricus MM 739 ACS89077.1    
 TSIB_0091   Thermococcus sibiricus MM 739 ACS89159.1    
 TSIB_1217   Thermococcus sibiricus MM 739 ACS90271.1    
 TSIB_1274   Thermococcus sibiricus MM 739 ACS90328.1    
 TSIB_1823   Thermococcus sibiricus MM 739 ACS90874.1    
 TSIB_2026   Thermococcus sibiricus MM 739 ACS91073.1    
 TSIB_2050   Thermococcus sibiricus MM 739 ACS91097.1    
 TSIB_0480   Thermococcus sibiricus MM 739 ACS89546.1    
 TSIB_2059   Thermococcus sibiricus MM 739 ACS91106.1    
 A3L11_10235   Thermococcus siculi RG-20 ASJ09587.1    
 A3L11_03670   Thermococcus siculi RG-20 ASJ08378.1    
 A3L11_04035   Thermococcus siculi RG-20 ASJ08444.1    
 A3L11_03680   Thermococcus siculi RG-20 ASJ08379.1    
 A3L11_00410   Thermococcus siculi RG-20 ASJ07772.1    
 A3L11_03495   Thermococcus siculi RG-20 ASJ08344.1    
 A3L11_03655   Thermococcus siculi RG-20 ASJ08375.1    
 A3L11_08415   Thermococcus siculi RG-20 ASJ09249.1    
 A3L11_03685   Thermococcus siculi RG-20 ASJ08380.1    
 A3L11_07770   Thermococcus siculi RG-20 ASJ09132.1    
 A3L11_02870   Thermococcus siculi RG-20 ASJ08225.1    
 A3L11_03660   Thermococcus siculi RG-20 ASJ08376.1    
 ADU37_CDS19490   Thermococcus sp. 2319x1 ALV63648.1    
 ADU37_CDS21750   Thermococcus sp. 2319x1 ALV63872.1    
 ADU37_CDS00110   Thermococcus sp. 2319x1 ALV61710.1    
 ADU37_CDS21580   Thermococcus sp. 2319x1 ALV63855.1    
 ADU37_CDS06110   Thermococcus sp. 2319x1 ALV62310.1    
 ADU37_CDS21610   Thermococcus sp. 2319x1 ALV63858.1    
 ADU37_CDS20040   Thermococcus sp. 2319x1 ALV63703.1    
 ADU37_CDS04100   Thermococcus sp. 2319x1 ALV62109.1    
 ADU37_CDS21890   Thermococcus sp. 2319x1 ALV63886.1    
 GQS_01290   Thermococcus sp. 4557 AEK72160.1    
 GQS_08670   Thermococcus sp. 4557 AEK73628.1    
 GQS_06840   Thermococcus sp. 4557 AEK73266.1    
 GQS_05565   Thermococcus sp. 4557 AEK73014.1    
 GQS_01955   Thermococcus sp. 4557 AEK72292.1    
 GQS_06080   Thermococcus sp. 4557 AEK73114.1    
 GQS_06820   Thermococcus sp. 4557 AEK73262.1    
 GQS_06830   Thermococcus sp. 4557 AEK73264.1    
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