Known Activities	cellulose synthase (EC 2.4.1.12); chitin synthase (EC 2.4.1.16); dolichyl-phosphate β-D-mannosyltransferase (EC 2.4.1.83); dolichyl-phosphate β-glucosyltransferase (EC 2.4.1.117); N-acetylglucosaminyltransferase (EC 2.4.1.-); N-acetylgalactosaminyltransferase (EC 2.4.1.-); hyaluronan synthase (EC 2.4.1.212); chitin oligosaccharide synthase (EC 2.4.1.-); β-1,3-glucan synthase (EC 2.4.1.34); β-1,4-mannan synthase (EC 2.4.1.-); β-mannosylphosphodecaprenol�mannooligosaccharide α-1,6-mannosyltransferase (EC 2.4.1.199); α-1,3-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism	Inverting
3D Structure Status	GT-A
Note	Distant similarity to families GT12, GT21, GT27, GT55, GT81 etc.
External resources	Callose Synthases/Glucan Synth; CesA pages at Stanford; CSL pages at Michigan state Un; HOMSTRAD; InterPro;
Statistics	GenBank accession (21856); Uniprot accession (10019); PDB accession (13); 3D entries (4); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
SpsA (BSU37910)		Bacillus subtilis subsp. subtilis str. 168	CAA51619.1 CAB15817.1 NP_391670.1	P39621	1H7L[A] 1H7Q[A] 1QG8[A] 1QGQ[A] 1QGS[A]
BF2801		Bacteroides fragilis NCTC 9343 ATCC 25285	CAH08495.1	Q5LBM4	3BCV[A,B]
chondroitin polymerase (KfoC;K4CP)	2.4.1.175 2.4.1.226	Escherichia coli K4	BAC00523.1 CAD87418.1 CAD87419.1 CAV13380.1 CAV13381.1	Q8L0V4	2Z86[A,B,C,D] 2Z87[A,B]
chondroitin polymerase (KfoC;K4CP)	2.4.1.175 2.4.1.226	Escherichia coli K4	BAC00523.1 CAD87418.1 CAD87419.1 CAV13380.1 CAV13381.1	Q8L0V4	2Z86[A,B,C,D] 2Z87[A,B]
teichoic acid polymerase (TagF;SE1960)		Staphylococcus epidermidis RP62A	AAW52851.1	Q5HLM5	3L7I[A,B,C,D] 3L7J[A,B,C,D] 3L7K[A,B,C,D] 3L7L[A,B,C,D] 3L7M[A,B,C,D]