GlycosylTransferase Family 113

Activities in FamilyGlucosyltransferase (2.4.1.-); Hexosyltransferase (2.4.1.-)
3D Structure StatusGT-B
NoteFamily created after Zhou et al. (2010) [PMID: 20164186] who demonstrated the glycosyltransferase activity in the Streptococcus parasanguinis protein Gtf3. The enzyme is predicted to have a retaining mechanism [PMID=21653318] based on structural similarity to GT4, GT5 and GT20 structures; however, direct proof of the stereochemistry of the glycosidic bond formed is missing.
Statistics GenBank accession (1227); Uniprot accession (4); PDB accession (3); 3D entries (2); cryst (0)
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 UDP-glucose: glucosyltransferase (GtfC; GBSCOH1_1238) 2.4.1.- Streptococcus agalactiae COH1 CDN66704.1 A0A0M3KKZ0
4W6Q[A] 2.70
 UDP-glucose: glucosyltransferase 3 (Gtf3;Nss;Spaf_1934) 2.4.1.- Streptococcus parasanguinis FW213 ACF35267.1
3QKW[A,B,C,D] 2.29
3RHZ[A,B] 1.90

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