Activities in Family	Hexosyltransferases (EC 2.4.1.-); [inverting] UDP-Galf: [LPS/O-antigen] α-glucoside β-1,6-galactofuranosyltransferase (EC 2.4.1.-);
3D Structure Status	GT-B
Note	Family created after Zhou et al. (2010) [PMID: 20164186] who demonstrated the glycosyltransferase activity in the Streptococcus parasanguinis protein Gtf3. The enzyme is predicted to have a retaining mechanism [PMID=21653318] based on structural similarity to GT4, GT5 and GT20 structures; however, direct proof of the stereochemistry of the glycosidic bond formed is missing.
Statistics	GenBank accession (1734); Uniprot accession (4); PDB accession (3); 3D entries (2); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
UDP-Glc: [Serine-rich repeat glycoprotein] N-acetylglucosaminide glucosyltransferase (GtfC; GBSCOH1_1238)	2.4.1.-	Streptococcus agalactiae COH1	CDN66704.1	A0A0M3KKZ0	4W6Q[A,B,C,D] 2.70
UDP-glucose: glucosyltransferase 3 (Gtf3;Nss;Spaf_1934)	2.4.1.-	Streptococcus parasanguinis FW213	ACF35267.1 AFJ26876.1	B5A7L9 I1ZPA2	3QKW[A,B,C,D] 2.29 3RHZ[A,B] 1.90
Top

Last update: 2024-04-25 © Copyright 1998-2024
AFMB - CNRS - Université d'Aix-Marseille