GlycosylTransferase Family 113

Activities in FamilyHexosyltransferases (EC 2.4.1.-);
[inverting] UDP-Galf: [LPS/O-antigen] α-glucoside β-1,6-galactofuranosyltransferase (EC 2.4.1.-);
3D Structure StatusGT-B
NoteFamily created after Zhou et al. (2010) [PMID: 20164186] who demonstrated the glycosyltransferase activity in the Streptococcus parasanguinis protein Gtf3. The enzyme is predicted to have a retaining mechanism [PMID=21653318] based on structural similarity to GT4, GT5 and GT20 structures; however, direct proof of the stereochemistry of the glycosidic bond formed is missing.
Statistics GenBank accession (1745); Uniprot accession (4); PDB accession (3); 3D entries (2); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 UDP-Galf: [LPS/O-antigen] α-glucoside β-1,6-galactofuranosyltransferase (WbbI;yefG;Orf8;b2034) 2.4.1.- pubmed
Escherichia coli K-12 CQR81552.1    
 UDP-Glc: [Serine-rich repeat glycoprotein] N-acetylglucosaminide glucosyltransferase (GtfC; GBSCOH1_1238) 2.4.1.- pubmed
Streptococcus agalactiae COH1 CDN66704.1 A0A0M3KKZ0 4W6Q[A,B,C,D]
 UDP-glucose: glucosyltransferase 3 (Gtf3;Nss;Spaf_1934) 2.4.1.- pubmed
Streptococcus parasanguinis FW213 ACF35267.1
AFJ26876.1
B5A7L9
I1ZPA2
3QKW[A,B,C,D]
3RHZ[A,B]
 UDP-Glc: glucosyltransferase (Gtf3;SP1768;SP_1768) 2.4.1.- pubmed
Streptococcus pneumoniae TIGR4 AAK75843.1 A0A0H2UR93  
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