Glycoside Hydrolase Family 98

Activities in Family	Blood-group endo-β-1,4-galactosidase (EC 3.2.1.102); Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism	Inverting e
3D Structure Status	( β / α ) ₈ barrel
Catalytic Nucleophile/Base	Asp+Glu diad
Catalytic Proton Donor	Glu
Note	Created after Anderson et al. (J. Biol. Chem. 2005 280: 7720-7728; PMID:15618227)
External resources	CAZypedia;
Statistics	GenBank accession (555); Uniprot accession (10); PDB accession (19); 3D entries (3); cryst (0)


Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D
corn-bran specific endo-β-1,4-xylanase (BACOVA_03433; Bovatus_03729)	3.2.1.8	pubmed	Bacteroides ovatus ATCC 8483	ALJ48334.1 EDO10800.1	A7M006
blood group A- and B-cleaving endo-β-galactosidase (Endo-ABase;EabC)	3.2.1.102	pubmed	Clostridium perfringens ATCC 10543	AAR84225.1	Q6RUF5 Q8XNK4
blood group A- and B-cleaving endo-β-galactosidase (Cpe0329)	3.2.1.102	pubmed	Clostridium perfringens str. 13	BAB80035.1 NP_561245.1	Q8XNK4
blood-group endo-β-1,4-galactosidase (RgGH98;FXV78_04990)	3.2.1.102	pubmed	Mediterraneibacter gnavus ATCC 29149 JCM6515	QEI31357.1	A7B6A6	7PMO[A,B] 7Q1W[A] 7Q20[A,B]
endo-β-1,4-galactosidase (CGSSp3BS71_10403;Sp3GH98;EABase) (blood-group A/B-antigen-specific)	3.2.1.102	pubmed	Streptococcus pneumoniae SP3-BS71	EDK74349.1	A0A0H2UKY3 A0A0H2UKY4 A5LBQ0 C1CB04	2WMI[A,B] 2WMJ[A,B] 2WMK[A,B] 4D6C[A] 4D6D[A] 4D6E[A] 4D6F[A] 4D6G[A] 4D6H[A] 4D6I[A] 4D6J[A] 4D71[A] 4D72[A]
endo-β-1,4-galactosidase (SP_2159;SP2159;Sp4GH98) (LewisY-specific)	3.2.1.102	pubmed	Streptococcus pneumoniae TIGR4	AAK76213.1 AAY71778.1 NP_346573.1	A0A0H2US34 Q97N96	2WMF[A] 2WMG[A] 2WMH[A]
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