Glycoside Hydrolase Family 7

Activities in Familyendo-β-1,4-glucanase (EC 3.2.1.4); reducing end-acting cellobiohydrolase (EC 3.2.1.176); chitosanase (EC 3.2.1.132); endo-β-1,3-1,4-glucanase (EC 3.2.1.73)
Mechanism Retaining
ClanGH-B
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family C. The cellobiohydrolases of this family act processively from the reducing ends of cellulose chains to generate cellobiose. This is markedly different from the IUBMB definition of cellobiohydrolases (EC 3.2.1.91), which act from the non-reducing ends of cellulose.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (10571); Uniprot accession (528); PDB accession (84); 3D entries (17); cryst (0)
All (5106) Bacteria (10) Eukaryota (5092) unclassified (4) Structure (17) Characterized (84)
| 1 | 2 | 3 | 4 | 5 | 6 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CBHI (fragment)   uncultured fungus ABY70686.1 B0FX52  
 CBHI (fragment)   uncultured fungus ABY70687.1
ABY70688.1
ABY70689.1
B0FX53  
 CBHI (fragment)   uncultured fungus ABY70690.1 B0FX56  
 CBHI (fragment)   uncultured fungus ABY70691.1 B0FX57  
 CBHI (fragment)   uncultured fungus ABY70692.1 B0FX58  
 CBHI (fragment)   uncultured fungus ABY70693.1 B0FX59  
 CbhI / C73 (fragment)   uncultured soil fungus AFX69289.1    
 CbhI / C12 (fragment)   uncultured soil fungus AFX69282.1    
 CbhI / C35 / C36 (fragment)   uncultured soil fungus AFX69283.1
AFX69284.1
   
 CbhI / C55 (fragment)   uncultured soil fungus AFX69285.1    
 CbhI / C53 (fragment)   uncultured soil fungus AFX69286.1    
 CbhI / C43 (fragment)   uncultured soil fungus AFX69287.1    
 CbhI / C62 (fragment)   uncultured soil fungus AFX69288.1    
 CbhI / C14 (fragment)   uncultured soil fungus AFX69290.1    
 SM2734A30   uncultured symbiotic protist of Cryptocercus punctulatus BAF57462.1 A4UX52  
 SM2734B07   uncultured symbiotic protist of Cryptocercus punctulatus BAF57463.1 A4UX53  
 SM2734B90;SM2735A96   uncultured symbiotic protist of Cryptocercus punctulatus BAF57464.1
BAF57465.1
A4UX54  
 SM2737B11;SM2737B15;SM2738A85;SM2739A85   uncultured symbiotic protist of Cryptocercus punctulatus BAF57466.1
BAF57467.1
BAF57469.1
BAF57470.1
A4UX56  
 SM2738A50   uncultured symbiotic protist of Cryptocercus punctulatus BAF57468.1 A4UX58  
 NT0285B24   uncultured symbiotic protist of Hodotermopsis sjoestedti BAF57342.1 A4UWT2  
 NT0288A79   uncultured symbiotic protist of Hodotermopsis sjoestedti BAF57343.1 A4UWT3  
 NT0291B13   uncultured symbiotic protist of Hodotermopsis sjoestedti BAF57344.1 A4UWT4  
 SM2767A62   uncultured symbiotic protist of Mastotermes darwiniensis BAF57430.1 A4UX20  
 SM2760A42   uncultured symbiotic protist of Mastotermes darwiniensis BAF57416.1 A4UX06  
 SM2760A82   uncultured symbiotic protist of Mastotermes darwiniensis BAF57417.1 A4UX07  
 SM2760B38   uncultured symbiotic protist of Mastotermes darwiniensis BAF57418.1
BAF57421.1
BAF57422.1
BAF57428.1
A4UX08  
 SM2763A63   uncultured symbiotic protist of Mastotermes darwiniensis BAF57419.1 A4UX09  
 SM2765A40   uncultured symbiotic protist of Mastotermes darwiniensis BAF57420.1 A4UX10  
 SM2766A71   uncultured symbiotic protist of Mastotermes darwiniensis BAF57423.1 A4UX13  
 SM2766A84   uncultured symbiotic protist of Mastotermes darwiniensis BAF57424.1 A4UX14  
 SM2766A85   uncultured symbiotic protist of Mastotermes darwiniensis BAF57425.1 A4UX15  
 SM2766B13   uncultured symbiotic protist of Mastotermes darwiniensis BAF57426.1 A4UX16  
 SM2766B38   uncultured symbiotic protist of Mastotermes darwiniensis BAF57427.1 A4UX17  
 SM2767A59   uncultured symbiotic protist of Mastotermes darwiniensis BAF57429.1 A4UX19  
 SM2632A01   uncultured symbiotic protist of Neotermes koshunensis BAF57374.1 A4UWW4  
 SM2632A27;SM2632B65   uncultured symbiotic protist of Neotermes koshunensis BAF57375.1
BAF57379.1
A4UWW5  
 SM2632B04   uncultured symbiotic protist of Neotermes koshunensis BAF57376.1 A4UWW6  
 SM2632B30   uncultured symbiotic protist of Neotermes koshunensis BAF57377.1 A4UWW7  
 SM2632B35   uncultured symbiotic protist of Neotermes koshunensis BAF57378.1 A4UWW8  
 SM2634A36   uncultured symbiotic protist of Neotermes koshunensis BAF57380.1 A4UWX0  
 SM2634A56   uncultured symbiotic protist of Neotermes koshunensis BAF57381.1 A4UWX1  
 SM2634A83;SM2636A53   uncultured symbiotic protist of Neotermes koshunensis BAF57382.1
BAF57390.1
A4UWX2  
 SM2634B21   uncultured symbiotic protist of Neotermes koshunensis BAF57383.1 A4UWX3  
 SM2634B52   uncultured symbiotic protist of Neotermes koshunensis BAF57384.1 A4UWX4  
 SM2634B62   uncultured symbiotic protist of Neotermes koshunensis BAF57385.1 A4UWX5  
 SM2634B70   uncultured symbiotic protist of Neotermes koshunensis BAF57386.1 A4UWX6  
 SM2635A22   uncultured symbiotic protist of Neotermes koshunensis BAF57387.1 A4UWX7  
 SM2636A30   uncultured symbiotic protist of Neotermes koshunensis BAF57388.1 A4UWX8  
 SM2636A43   uncultured symbiotic protist of Neotermes koshunensis BAF57389.1 A4UWX9  
 SM2636A55   uncultured symbiotic protist of Neotermes koshunensis BAF57391.1 A4UWY1  
 SM2636B56   uncultured symbiotic protist of Neotermes koshunensis BAF57392.1 A4UWY2  
 SM2636B71   uncultured symbiotic protist of Neotermes koshunensis BAF57393.1 A4UWY3  
 SM2637A29   uncultured symbiotic protist of Neotermes koshunensis BAF57395.1 A4UWY5  
 SM2637A72   uncultured symbiotic protist of Neotermes koshunensis BAF57396.1 A4UWY6  
 SM2637B39   uncultured symbiotic protist of Neotermes koshunensis BAF57397.1 A4UWY7  
 SM2649B83   uncultured symbiotic protist of Neotermes koshunensis BAF57398.1 A4UWY8  
 SM2637A18   uncultured symbiotic protist of Neotermes koshunensis BAF57394.1 A4UWY4  
 SM2038A06   uncultured symbiotic protist of Reticulitermes speratus BAF57294.1 A4UWN4  
 SM2038A74   uncultured symbiotic protist of Reticulitermes speratus BAF57295.1 A4UWN5  
 endo-β-1,4-glucanase (RsSymEG1;RsSym EG I;RsSymEG;SM2038B11) 3.2.1.4 uncultured symbiotic protist of Reticulitermes speratus BAF57296.1 A4UWN6  
 SM2038B27   uncultured symbiotic protist of Reticulitermes speratus BAF57297.1 A4UWN7  
 SM2038B47   uncultured symbiotic protist of Reticulitermes speratus BAF57298.1 A4UWN8  
 SM2039A06   uncultured symbiotic protist of Reticulitermes speratus BAF57299.1 A4UWN9  
 SM2039A17   uncultured symbiotic protist of Reticulitermes speratus BAF57300.1 A4UWP0  
 SM2039A20   uncultured symbiotic protist of Reticulitermes speratus BAF57301.1 A4UWP1  
 SM2039A22   uncultured symbiotic protist of Reticulitermes speratus BAF57302.1 A4UWP2  
 SM2039A92   uncultured symbiotic protist of Reticulitermes speratus BAF57303.1 A4UWP3  
 SM2039A93   uncultured symbiotic protist of Reticulitermes speratus BAF57304.1 A4UWP4  
 SM2040A65   uncultured symbiotic protist of Reticulitermes speratus BAF57305.1 A4UWP5  
 SM2040B92   uncultured symbiotic protist of Reticulitermes speratus BAF57306.1 A4UWP6  
 SM2041A02   uncultured symbiotic protist of Reticulitermes speratus BAF57307.1 A4UWP7  
 SM2041A43   uncultured symbiotic protist of Reticulitermes speratus BAF57308.1 A4UWP8  
 SM2041A63   uncultured symbiotic protist of Reticulitermes speratus BAF57309.1 A4UWP9  
 SM2042A32   uncultured symbiotic protist of Reticulitermes speratus BAF57310.1 A4UWQ0  
 SM2042B16   uncultured symbiotic protist of Reticulitermes speratus BAF57311.1 A4UWQ1  
 RsSym7cbh1 (SM2042B48)   uncultured symbiotic protist of Reticulitermes speratus BAF57312.1
BAG71491.1
A4UWQ2  
 SM2042B83   uncultured symbiotic protist of Reticulitermes speratus BAF57313.1 A4UWQ3  
 SM2038A58   uncultured symbiotic protist of Reticulitermes speratus BAF57314.1 A4UWQ4  
 SM2042B24   uncultured symbiotic protist of Reticulitermes speratus BAF57315.1 A4UWQ5  
 cellobiohydrolase (Cbh) (fragment)   Verticillium dahliae 76 AAX73420.1 Q56NJ4  
 unnamed protein product   Verticillium tenerum CAD79783.1    
 CBH1 (fragment)   Volvariella bombycina 427_37 AEO14795.1    
 CBH1 (fragment)   Volvariella bombycina DSMZ62950 AEN92166.1    
 CBH1 (fragment)   Volvariella bombycina DSMZ62950 AEN92172.1    
 CBH1 (fragment)   Volvariella bombycina DSMZ62950 AEN92173.1    
 CBH1 (fragment)   Volvariella bombycina DSMZ62950 AEN92174.1    
 CBH1 (fragment)   Volvariella volvacea DSMZ62950 AEN92165.1    
 cellobiohydrolase I-II (CbhI-II)   Volvariella volvacea V14 AAT64007.1 Q6E5B2  
 cellobiohydrolase I-I (CbhI-I)   Volvariella volvacea V14 AAT64006.1 Q6E5B3  
 cellobiohydrolase I (CbhI) 3.2.1.176 Volvariella volvacea V14 AAD41096.1
AAD41096.2
Q9Y895  
 unnamed protein product   Xylaria hypoxylon CAD79789.1    
 CBHI (fragment)   Xylaria polymorpha ABY61355.1 B0FQ74  
 CBHI (fragment)   Xylaria polymorpha ABY61356.1 B0FQ75  
 CBHI (fragment)   Xylaria polymorpha ABY61357.1 B0FQ76  
 CBHI (fragment)   Xylaria polymorpha ABY61358.1 B0FQ77  
 CBHI (fragment)   Xylaria polymorpha ABY61359.1 B0FQ78  
 CBHI (fragment)   Xylaria polymorpha ABY61360.1 B0FQ79  
 CBHI (fragment)   Xylaria polymorpha ABY61361.1 B0FQ80  
 ZT1A5_G6041   Zymoseptoria tritici ST99CH_1A5 SMY24600.1    
 ZT1E4_G6132   Zymoseptoria tritici ST99CH_1E4 SMR52857.1    
 ZT3D1_G6025   Zymoseptoria tritici ST99CH_3D1 SMR54243.1    
 ZT3D7_G6090   Zymoseptoria tritici ST99CH_3D7 SMQ50937.1    
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Sequence 8 from patent US 7452707.   unidentified ACK24686.1    
 Sequence 11 from patent US 7452707.   unidentified ACK24688.1    
 Sequence 14 from patent US 7452707.   unidentified ACK24690.1    
 Sequence 16 from patent US 7452707.   unidentified ACK24692.1    
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