| Activities in Family | β-4-O-methyl-glucuronidase (EC 3.2.1.-); Glycyrrhizin β-glucuronidase (EC 3.2.1.128); Heparanase / endo-β-glucuronidase (EC 3.2.1.166); Baicalin β-glucuronidase (EC 3.2.1.167); β-glucuronidase (EC 3.2.1.31); Hyaluronidase / hyaluronoglucuronidase (EC 3.2.1.36); |
|---|---|
| Mechanism | Retaining (inferred) e |
| Clan | GH-A |
| 3D Structure Status | ( β / α ) 8 (inferred) |
| Catalytic Nucleophile/Base | Glu (inferred) |
| Catalytic Proton Donor | Glu (inferred) |
| External resources | CAZypedia; |
| Statistics | GenBank accession (1427); Uniprot accession (23); PDB accession (48); 3D entries (5); cryst (0) |
| Bacteria | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| β-glucuronidase (ACP_2665;AcGlcA79A) (GlcA79A) | 3.2.1.31 | pubmed |
Acidobacterium capsulatum ATCC 51196 | ACO32043.1 | C1F2K5 | 3VNY[A] 3VNZ[A] 3VO0[A] 5G0M[A] 5G0Q[A] 5L77[A] 7PSH[A] 7PSI[A] 7PSJ[A] 7PSK[A] 8B0D[A] 8B0E[A] 8OGX[A] 8OHT[A] 8OHU[A] 8OHV[A] |
|
| heparanase / endo-β-glucuronidase (BpHep;DP46_278) | 3.2.1.166 | pubmed |
Burkholderia pseudomallei BEK | AIO87434.1 | Q63T97 | 5BWI[A,B] 7PR9[A,B] 7PRB[A,B] 8OHW[A,B] |
|
| Eukaryota | |||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | |
| β-glucuronidase (GUS2;AtGus2;At5g07830) | 3.2.1.31 | pubmed |
Arabidopsis thaliana | BAB09947.1 AAU05468.1 AAU93572.1 AED91209.1 CAB62595.1 NP_196400.2 |
A0A654FZP1 Q9FF10 Q9SDA1 |
||
| β-glucuronidase / β-4-O-methyl-glucuronidase (AnGlcAase;An02g11890) | 3.2.1.31 3.2.1.- |
pubmed pubmed |
Aspergillus niger CBS 513.88 | CAK96418.1 | A2QEQ6 | ||
| heparanase 1 (Hpse1;Hpse;CH211-85E10.3-001) | 3.2.1.166 | pubmed |
Danio rerio | CAK05012.1 AAI39575.1 NP_001038470.1 |
A0A8M1N9R1 A4QNY9 Q1LVP9 |
||
| 4-O-α-L-rhamnosyl-β-D-glucuronidase (FoBGlcA) | 3.2.1.31 | pubmed |
Fusarium oxysporum 12S | BCB92231.1 | A0A7I8AV45 | 7DFQ[A] 7DFS[A] |
|
| heparanase | 3.2.1.166 | pubmed |
Gallus gallus | AAK82648.1 AAS29152.1 |
Q90YK5 | ||
| hyaluronidase (LHyal) | 3.2.1.36 | pubmed |
Hirudo nipponia | AHV78514.1 | X4Y2L4 | 7EYO[A] | |
| heparanase (endo-β-glucuronidase) (Hpa1Hpr1;HEP;HPA;HPSE1;HSE1;hHep;Hs.44227) | 3.2.1.166 | pubmed |
Homo sapiens | AAD45669.1 AAD41342.1 AAD45379.1 AAD54516.1 AAD54941.1 AAE32409.1 AAE58088.1 AAE73533.1 AAE73534.1 AAH51321.1 AAN25813.1 AAN93460.1 AAN97232.1 AAP02795.1 AAQ27145.1 AAS22726.1 AAS22727.1 AAS29151.1 AAS29153.1 AAT15085.1 AAW00328.1 AAW04303.1 AAW04304.1 AAW06749.1 AAX47106.1 ABA68377.1 ABC06425.1 ABC06426.1 ABE17595.1 ABH84630.1 ABI07172.1 ABJ35310.1 ACQ12348.1 ACT98237.1 ACT98238.1 BAD96706.1 BAG52128.1 CAC10139.1 CAC10140.1 CAC39726.1 CAC41180.1 CAH05691.1 CAH05692.1 CAH05695.1 CAH05696.1 CAI40110.1 CAI40111.1 CAI72097.1 CAL14864.1 CAL14865.1 CAL91960.1 NP_006656.1 |
B3KQR6 Q9UL39 Q9Y251 |
5E8M[A] 5E97[A] 5E98[A] 5E9B[A] 5E9C[A] 5L9Y[A] 5L9Z[A] 5LA4[A] 5LA7[A] 6ZDM[AAA] 7PR7[A] 7PR8[A] 7PRT[A] 7RG8[A] 7YI7[A] 7YJC[A] 8B0B[A] 8B0C[A] 8BAC[A] 8CQI[A] 8E07[A] 8E08[A] 8JYG[A] 8OHQ[A] 8OHR[A] |
|
| heparanase (Hpa;HpsE) | 3.2.1.166 | pubmed |
Mus musculus | AAL76083.1 AAE73535.1 AAN41636.1 AAQ15188.1 AAS22728.1 AAS29149.1 AAW04306.1 ABC06428.1 BAC30600.1 BAE32725.1 CAC10141.1 NP_690016.1 |
B2RS99 Q6YGZ1 |
||
| β-glucuronidase (Nc6GAL;NCU00937.1) | 3.2.1.31 | pubmed |
Neurospora crassa OR74A | BAF75800.1 XP_964763.1 |
A7M6H1 Q7SFB0 |
||
| heparanase (HpsE;Hep) | 3.2.1.166 | pubmed |
Rattus norvegicus | AAF04563.1 AAE73536.1 AAQ15189.1 AAS29150.1 CAC10143.1 NP_072127.1 |
Q71RP1 Q9QZF8 |
||
| baicalin β-glucuronidase (SguS) | 3.2.1.167 | pubmed |
Scutellaria baicalensis | BAA97804.1 | Q9LRC8 | ||
| glycyrrhizin β-glucuronidase (TpGUS79A) | 3.2.1.128 | pubmed |
Talaromyces pinophilus Li-93 | AQW38601.1 | A0A1S6QV69 | ||
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