Glycoside Hydrolase Family 79

Known Activitiesβ-glucuronidase (EC 3.2.1.31); β-4-O-methyl-glucuronidase (EC 3.2.1.-); heparanase (EC 3.2.1.-)
Mechanism Retaining (inferred)
ClanGH-A
3D Structure Status( β / α ) 8 (inferred)
Catalytic Nucleophile/BaseGlu (inferred)
Catalytic Proton DonorGlu (inferred)
External resourcesInterPro; PFAM;
Statistics GenBank accession (238); Uniprot accession (59);
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 β-glucuronidase (GUS2;AtGus2;At5g07830) 3.2.1.- Arabidopsis thaliana AAU05468.1
AAU93572.1
BAB09947.1
CAB62595.1
NP_196400.2
Q9FF10
Q9SDA1
 
 β-glucuronidase / β-4-O-methyl-glucuronidase (An02g11890) 3.2.1.-
3.2.1.31
Aspergillus niger CBS 513.88 CAK96418.1 A2QEQ6  
 heparanase (HpsE) 3.2.1.- Bos taurus AAF87301.2
NP_776507.1
Q9MYY0  
 heparanase 3.2.1.- Gallus gallus AAK82648.1
AAS29152.1
Q90YK5  
 hyaluronidase 3.2.1.- Hirudinaria manillensis ABH83946.1    
 hyaluronidase 3.2.1.- Hirudinaria manillensis ABH83949.1
CAC22595.1
   
 hyaluronidase 3.2.1.- Hirudinaria manillensis ABH83948.1
CAC22594.1
   
 hyaluronidase 3.2.1.- Hirudinaria manillensis ABH83947.1
CAC22593.1
   
 heparanase (endo-β-glucuronidase) (HPA) 3.2.1.- Homo sapiens AAD41342.1
AAD45379.1
AAD45669.1
AAD54516.1
AAD54941.1
AAE32409.1
AAE58088.1
AAE73533.1
AAE73534.1
AAH51321.1
AAN25813.1
AAN93460.1
AAN97232.1
AAP02795.1
AAQ27145.1
AAS22726.1
AAS22727.1
AAS29151.1
AAS29153.1
AAT15085.1
AAW00328.1
AAW04303.1
AAW04304.1
AAW06749.1
AAX47106.1
ABA68377.1
ABC06425.1
ABC06426.1
ABE17595.1
ABH84630.1
ABI07172.1
ABJ35310.1
ACQ12348.1
ACT98237.1
ACT98238.1
BAD96706.1
BAG52128.1
CAC10139.1
CAC10140.1
CAC39726.1
CAC41180.1
CAH05691.1
CAH05692.1
CAH05695.1
CAH05696.1
CAI40110.1
CAI40111.1
CAI72097.1
CAL14864.1
CAL14865.1
CAL91960.1
NP_006656.1
Q9UL39
Q9Y251
 
 heparanase (Hpa;HpsE) 3.2.1.- Mus musculus AAE73535.1
AAL76083.1
AAN41636.1
AAQ15188.1
AAS22728.1
AAS29149.1
AAW04306.1
ABC06428.1
BAC30600.1
BAE32725.1
CAC10141.1
NP_690016.1
B2RS99
Q6YGZ1
 
 β-glucuronidase (Nc6GAL;NCU00937.1) 3.2.1.31 Neurospora crassa OR74A BAF75800.1
XP_964763.1
   
 heparanase (HpsE;Hep) 3.2.1.- Rattus norvegicus AAE73536.1
AAF04563.1
AAQ15189.1
AAS29150.1
CAC10143.1
NP_072127.1
Q71RP1
Q9QZF8
 
 β-glucuronidase (SGUS) 3.2.1.- Scutellaria baicalensis BAA97804.1 Q9LRC8  

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.