Glycoside Hydrolase Family 76

Activities in Familyα-1,6-mannanase (EC 3.2.1.101); α-glucosidase (EC 3.2.1.20)
Mechanism Retaining
3D Structure Status( α / α ) 6 barrel
Catalytic Nucleophile/BaseAsp (inferred from 3-D structure)
Catalytic Proton DonorAsp (inferred from 3-D structure)
External resourcesCAZypedia;
Statistics GenBank accession (3070); Uniprot accession (10); PDB accession (29); 3D entries (8); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 α-1,6-mannanase (BtGH76-MD40;Btheta7330_05006) 3.2.1.101 pubmed
Bacteroides thetaiotaomicron 7330 ALJ44520.1 A0A0P0FW82 6U4Z[A]
 endo-α-1,6-mannanase (BT3782;BT_3782) 3.2.1.101 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO78887.1
NP_812693.1
Q8A184 4MU9[A,B]
 endo-α-1,6-mannanase (BT2631) 3.2.1.101 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO77738.1
NP_811544.1
Q8A4G8  
 endo-α-1,6-mannanase (BT2623) 3.2.1.101 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO77730.1
NP_811536.1
Q8A4H6  
 endo-α-1,6-mannanase (BT3792) 3.2.1.101 pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO78897.1
NP_812703.1
Q8A174 4C1S[A,B]
 endo-α-1,6-mannanase (Aman6) 3.2.1.101 pubmed
Niallia circulans TN31 / TN-31 BAA75632.1 Q9Z4P9 B[nd]
4BOJ[A,B,C]
4BOK[A]
4D4A[A,B]
4D4B[A,B]
4D4C[A,B]
4D4D[A,B]
5AGD[A,B]
5M77[A,B]
5N0F[A,B]
6ZBM[A]
6ZBW[A]
6ZBX[A]
7NL5[A]
 α-glucosidase activity on pNP-α-D-maltopyranoside (STAUR_0381) 3.2.1.20 pubmed
Stigmatella aurantiaca DW4/3-1 ADO68190.1 Q08R12  
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 cell wall α-1,6-mannotransglycosylase / α-1,6-mannanase (Dcw1;GH76-3;NCU08127) 3.2.1.101 pubmed
Neurospora crassa OR74A EAA30434.1
XP_328833.1
Q7S4K4  
 cell wall α-1,6-mannotransglycosylase / α-1,6-mannanase (Dfg5;GH76-7;NCU03770) 3.2.1.101 pubmed
Neurospora crassa OR74A CAC28653.1
EAA31880.1
XP_323071.1
Q1K7A8
Q9C2J1
 
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