Glycoside Hydrolase Family 74

Activities in Family	Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150); Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Inverting e
3D Structure Status	7-fold β-propeller
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Asp (experimental)
External resources	CAZypedia;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (1567); Uniprot accession (35); PDB accession (19); 3D entries (12); cryst (0)

Summary

Download GH74 (2038) Taxonomic display Structure (12) Characterized (37)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
9832		Eutypa lata UCREL1 (Eutla1)
267757		Exidia glandulosa v1 (Exigl1)
916543		Fibulorhizoctonia sp. CBS 109695 (Fibsp1)
73885		Fistulina hepatica (Fishe1)
1364949		Fomes fomentarius CIRM-BRFM 1821 (Fomfom1)
18962		Fomitiporia mediterranea MF3/22 (Fomme1)
114581		Fomitiporia mediterranea MF3/22 (Fomme1)
162184		Fomitiporia mediterranea MF3/22 (Fomme1)
18948		Fomitiporia mediterranea MF3/22 (Fomme1)
glycoside hydrolase family 74		fungal sp. AAJ6	QIK02130.1
525394		Fusarium tricinctum MPI-SDFR-AT-0044 (Fustri1)
690482		Fusarium commune MPI-SDFR-AT-0072 (Fusco1)
HYE67_005088		Fusarium culmorum Class2-1B	QPC62857.1
NCS54_01421600		Fusarium falciforme Fu3.1	WAO96539.1
FGRAMCML3066_01t21557.1		Fusarium graminearum	CZS85835.1
SNK03_013116 (Cel74A)		Fusarium graminearum KSU23473	WXC67331.1
QX201_010284 (Cel74A)		Fusarium graminearum KSU23522	WXC50608.1
unnamed protein product		Fusarium graminearum PH-1	CEF88293.1
12432		Fusarium graminearum v1.0 (Fusgr1)
77857		Fusarium oxysporum f. sp. albedinis isolate 9 v1.0 (Fusoxalb1)
1368		Fusarium oxysporum f. sp. conglutinans race 2 54008 (PHW808) (Fusoxcon1)
7354		Fusarium oxysporum f. sp. cubense tropical race 4 54006 (II5) (Fusoxcub1)
10187		Fusarium oxysporum f. sp. lycopersici 4287 v2 (Fusox2)
14498		Fusarium oxysporum f. sp. lycopersici MN25 (FoMN25) NRRL 54003 (Fusoxlyc1)
22514		Fusarium oxysporum f. sp. melonis (FoMelon) NRRL 26406 (Fusoxmel1)
26124		Fusarium oxysporum f. sp. pisi HDV247 (Fusoxpis1)
20328		Fusarium oxysporum f. sp. radicis-lycopersici 26381 (CL57) (Fusoxrad1)
11860		Fusarium oxysporum f. sp. raphani 54005 (Fusoxrap1)
14695		Fusarium oxysporum f. sp. vasinfectum 25433 (Cotton) (Fusoxvas1)
FOBC_15716		Fusarium oxysporum Fo47	QKD61502.1
6661		Fusarium oxysporum Fo47 (FusoxFo47)
848339		Fusarium oxysporum MPI-CAGE-CH-0212 v1.0 (Fusoxys1)
648677		Fusarium oxysporum MPI-SDFR-AT-0094 v1.0 (Fusoxy1)
3035		Fusarium oxysporum NRRL 32931 (Fusox32931)
9150		Fusarium poae 2516 (Fuspo1)
8104		Fusarium proliferatum ET1 (Fuspro1)
4336		Fusarium proliferatum NRRL 62905 (Fuspr1)
HYE68_010979		Fusarium pseudograminearum Class2-1C	QPC80227.1
NXS19_010908		Fusarium pseudograminearum Fp22-2	UZP43092.1
505817		Fusarium redolens MPI-CAGE-AT-0023 v1.0 (Fusre1)
595595		Fusarium solani FSSC 5 v1.0 (Fusso1)
LCI18_010954		Fusarium solani-melongenae CRI 24-3	UPL00020.1
307596		Fusarium equiseti G328 (Fuseq1)
527024		Fusarium tricinctum F194 (Fustr1)
53608		Nectria haematococca mpVI 77-13-4 (Necha2)
FVRRES_10622		Fusarium venenatum A3/5	CEI70545.1
453446		Fusarium venenatum MPI-CAGE-CH-0201 (Fusven1)
8796		Fusarium verticillioides 7600 v2 (Fusve2)
GH74 xyloglucanase (Gh74A)		Ganoderma applanatum VKPM F-632	QCR98305.1
GH74 xyloglucanase (Gh74B)		Ganoderma applanatum VKPM F-632	QCR98306.1
Cellulose-growth-specific protein (G4mvx4)		Ganoderma boninense	VWO96677.1
559058		Ganoderma boninense G3 v1.0 (Ganbon1)
582963		Ganoderma boninense G3 v1.0 (Ganbon1)
416907		Ganoderma lucidum G.260125-1 v1.0 (Ganluc1)
6665		Ganoderma sinense ZZ0214-1 (Gansi1)
79119		Ganoderma sp. 10597 SS1 v1.0 (Gansp1)
2899536		Gautieria morchelliformis GMNE.BST v1.0 (Gaumor1_1)
262090		Geopyxis carbonaria DOB1671 v1.0 (Geocar1)
oligoxyloglucan reducing end-specific cellobiohydrolase (OXG-RCBH)	3.2.1.150	Geotrichum sp. M128	BAC22065.1 CAF02212.1 CAF02249.1	Q8J0D2	1SQJ[A,B] 2EBS[A,B]
xyloglucanase M128 (Xeg; XEG)	3.2.1.151	Geotrichum sp. M128	BAD11543.1	Q764N8	3A0F[A]
11394		Glarea lozoyensis ATCC 20868 (Glalo1)
965184		Gloeopeniophorella convolvens OM19405 v1.0 (Glocon1)
68887		Gloeophyllum trabeum ATCC 11539 (Glotr1_1)
885309		Guyanagaster necrorhiza MCA 3950 v1 (Guyne1)
1700334		Gymnopilus junonius AH 44721 v1.0 (Gymjun1)
952753		Gymnopus androsaceus JB14 v1 (Gyman1)
147986		Gymnopus luxurians FD-317 M1 (Gymlu1)
153951		Heterobasidion annosum v2.0 (Hetan2)
1092663		Hexagonia nitida CIRM-BRFM 1802 (Hexnit1)
35470		Hydnopolyporus fimbriatus CBS384.51 v1.0 (Hydfim1)
984055		Hydnopolyporus fimbriatus CBS384.51 v1.0 (Hydfim1)
120771		Hygrophoropsis aurantiaca ATCC 28755 v1.0 (Hygaur1)
1061721		Hymenopellis radicata IJFM A160 v1.0 (Hymrad1)
1109100		Hymenopellis radicata IJFM A160 v1.0 (Hymrad1)
1222401		Hymenopellis radicata IJFM A160 v1.0 (Hymrad1)
38886		Hypoxylon argillaceum CBS 527.63 v1.0 (Hyparg1)
167276		Hypoxylon crocopeplum CBS 119004 v1.0 (Hypcro1)
520470		Hypoxylon fragiforme CBS 206.31 v2.0 (Hypfra2)
260701		Hypoxylon monticulosum FL0542 v1.0 (Hypmon1)
425381		Hypoxylon sp. EC38 v3 (HypEC38_3)
275664		Hypoxylon sp. FL0543 v1.0 (HyFL0543_1)
106439		Hypoxylon sp. FL0890 v1.0 (HyFL0890_1)
369435		Hypoxylon sp. FL1284 v2.0 (HyFL1284_2)
201617		Hypoxylon sp. FL1857 v1.0 (HyFL1857_1)
668168		Hypoxylon sp. NC0597 v1.0 (HyNC0597_1)
648798		Hypoxylon sp. NC1633 v2.0 (HyNC1633_2)
69413		Hypoxylon submonticulosum NC0708 v2.0 (Hypsub2)
296511		Hypoxylon trugodes CBS 135444 v1.0 (Hyptru1)
190		Hypsizygus marmoreus 51987-8 (Hypma1)
681308		Ilyonectria sp. MPI-CAGE-AT-0026 v1.0 (Ilyeu1)
692362		Ilyonectria sp. MPI-CAGE-AT-0026 v1.0 (Ilyeu1)
763362		Ilyonectria sp. MPI-CAGE-AT-0134 v1.0(Neora1)
568564		Ilyonectria sp. MPI-CAGE-AT-0134 v1.0(Neora1)
1594115		Irpex lacteus v1.0 (Irplac1)
850564		Irpex lacteus v1.0 (Irplac1)
44530		Jaapia argillacea v1 (Jaaar1)
482418		Jimgerdemmania flammicorona AD002 (Jimfl_AD_1)
126636		Jimgerdemannia lactiflua OSC166217 (Jimlac1)
126635		Jimgerdemannia lactiflua OSC166217 (Jimlac1)
128836		Jimgerdemannia lactiflua OSC166217 (Jimlac1)
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