Glycoside Hydrolase Family 5 / Subf 9

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (591); Uniprot accession (79); PDB accession (13); 3D entries (2); cryst (0)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 exo-β-1,3-glucanase 1 (Exg1;AbEXG1) 3.2.1.58 Agaricus bisporus HORST U1 CAA63536.1 Q12539   9
 exo-β-1,3-glucanase (Anid-Bgl502;AN7533) 3.2.1.58 Aspergillus nidulans FGSC A4 EAA62113.1
ABF50886.1
C8VBL9
Q5AVZ7
  9
 An18g04100 (P2) 3.2.1.58 Aspergillus niger CBS 513.88 CAK43212.1 A2RAR6   9
 exo-β-1,3-glucanase (Exg1;ExgA) 3.2.1.58 Aspergillus oryzae CBS 12559 CAC07551.1
AHH92832.1
CAD97460.1
Q7Z9L3   9
 exo-β-1,3-glucanase (Exg1;AO090003000990) 3.2.1.58 Aspergillus oryzae RIB40 BAE58099.1 Q7Z9L3   9
 exo-β-1,3-glucanase (Exg2) 3.2.1.58 Bipolaris zeicola AAF65310.1 Q9P8N7   9
 exo-β-1,3-glucanase (Xog;Xog1;Exg;Ca49c10.05) 3.2.1.58 Candida albicans CAA39908.1
AAV05307.1
CAA21969.1
P29717 1CZ1[A]
1EQC[A]
1EQP[A]
2PB1[A]
2PBO[A]
2PC8[A]
2PF0[A]
3N9K[A]
3O6A[A]
4M80[A]
4M81[A]
4M82[A]
9
 exo-β-1,3-glucanase (Exg1) 3.2.1.58 Candida oleophila AAM21469.1 Q8NKF9   9
 exo-β-1,3-glucanase (Eg;Exg1) 3.2.1.58 Komagataella pastoris X-33 AAY28969.1 Q2TCV2   9
 PAS_chr2-1_0454 (Exg;Exg1) 3.2.1.58 Komagataella phaffii GS115 CAY69081.1
AOA67579.1
C4R0Q7   9
 exo-β-1,3-glucanase (Exg1) 3.2.1.58 Lentinula edodes H600 BAD97445.1
BAD97446.1
Q53UH0   9
 exo-1,3-glucanase (Exg1) 3.2.1.58 Pichia angusta ATCC 14754 CAA86948.1 Q12626   9
 exo-β-1,3-glucanase (Glu1;GLU1;PTRG_04560) 3.2.1.58 Pyrenophora tritici-repentis Alg3-24 EDU47467.1     9
 exo-β-1,3-glucanase (sporulation) (Spr1;Ssg1) 3.2.1.58 Saccharomyces cerevisiae GRF88 AAB24895.1
CAA41952.1
CAA99399.1
P32603   9
 exo-β-1,3-glucanase / flavonoid β-glucosidase (sporulation) (Ssg1;Spr1;YOR190W) 3.2.1.21
3.2.1.58
Saccharomyces cerevisiae S288c AAU09785.1
NP_014833.1
P32603   9
 exo-β-1,3-glucanase 1 / flavonoid β-glucosidase (Exg1;Bgl1;Scw6;YLR300W) 3.2.1.21
3.2.1.58
Saccharomyces cerevisiae S288c AAA34599.1
AAB67345.1
AAT93088.1
NP_013403.1
P23776 1H4P[A,B] 9
 exo-1,3-glucanase 2 (Exg2;YDR261c) 3.2.1.58 Saccharomyces cerevisiae S288c CAA86950.1
CAA92719.1
CAA94100.1
NP_010547.1
P52911   9
 endo-β-1,6-glucanase (Exg1;SPBC1105.05) 3.2.1.75 Schizosaccharomyces pombe 972h- CAB50968.1
NP_596461.1
Q9URU6   9
 exo-β-1,3-glucanase (Exg1) 3.2.1.58 Schwanniomyces occidentalis ATCC 26077 CAA86951.1 Q12700   9
 exo-β-1,3-glucanase (Exg2;PaEXG2;WaEXG2) 3.2.1.58 Wickerhamomyces anomalus K / NCYC 432 CAA11018.1 O93983   9
 exo-β-1,3-glucanase (Exg1;WsExg1) 3.2.1.58 Williopsis saturnus WC91-2 ACP74152.2
ACP74152.1
C3VMY4   9
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