Activities in Family	3-O-β-L-arabinopyranosyl-α-L-arabinofuranosidase (EC 3.2.1.-); Endo-α-L-rhamnosidase (EC 3.2.1.-); β-glucosidase (EC 3.2.1.21); 3-O-α-D-galactosyl-α-L-arabinofuranosidase (EC 3.2.1.215); β-galactosidase (EC 3.2.1.23); Xylan β-1,4-xylosidase (EC 3.2.1.37); Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); α-L-iduronidase (EC 3.2.1.76);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
External resources	CAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)	PROZOMIX;
Statistics	GenBank accession (5752); Uniprot accession (45); PDB accession (29); 3D entries (10); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
BcellWH2_03314 (GH39wh2)		Bacteroides cellulosilyticus WH2	ALJ60547.1		5JVK[A,B,C] 2.50
β-xylosidase II (XynB2;CcXynB2;CC2357)	3.2.1.37	Caulobacter vibrioides CB15	AAK24328.1 NP_421160.1	Q9A5U0	4EKJ[A] 2.50 4M29[A] 2.10
β-xylosidase (DtXyl; DICTH_1792)	3.2.1.37	Dictyoglomus thermophilum H-6-12	ACI18502.1	B5YB78	6YYH[A,B] 2.72 6YYI[A,B] β-D-Xylp 2.67
β-xylosidase (XynB;XynB1;HUS_CDS69)	3.2.1.37	Geobacillus stearothermophilus T-6 NCIMB 40222	ABI49941.1 AAC98129.1	Q9ZFM2	1W91[A,B,C,D,E,F,G,H] 2.2 2BFG[A,B,C,D,E,F,G,H] L-1-deoxy-Xylp α-D-Xylp-(1-4)-GLU β-D-Xylp-(1-1)-<non_carb> 2.40 2BS9[A,B,C,D,E,F,G,H] 2.2
exopolysaccharide Psl biosynthetic/hydrolytic enzyme (PslG; PA2237)	3.2.1.21	Pseudomonas aeruginosa PAO1	AAG05625.1 NP_250927.1	Q9I1N2	4ZN2[A,B,C,D] 2.00 5BX9[A] 2.00 5BXA[A] α-D-Manp 1.90
α-L-iduronidase (BAE36_24485)		Rhizobium leguminosarum bv. trifolii Rt24.2	AOO92540.1		5NDX[A] α-L-IdopA-(1-1)-<non_carb> 2.20
β-xylosidase (XynB)	3.2.1.37	Thermoanaerobacterium saccharolyticum B6A-RI	AAA27369.1	P36906	1PX8[A,B] β-D-Xylp 2.40 1UHV[A,B,C,D] α-D-Xylp2F-(1-4)-GLU 2.10
β-xylosidase (XynB; XacXynB; XAC4058)	3.2.1.37	Xanthomonas citri pv. citri str. 306	AAM38893.1 NP_644357.1	Q8PFC5	6UQJ[A] 1.71
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
α-L-iduronidase (IduA)	3.2.1.76	Homo sapiens	AAA81589.1 AAA51698.1 AAE53576.1 AAE72581.1 AAH29959.1 AAN25812.1 AAQ32908.1 AAQ46779.1 AAT18792.1 AAY01759.1 ABH73761.1 ABL21590.1 ACG93377.1 ACH14961.1 ACK10791.1 AFR32586.1 ASX95248.1 ASX95249.1 BAD92138.1 BAF84505.1 BAG54168.1 NP_000194.1 XP_042678.2	A0A286RYY1 A0A286RZ47 A8K701 J9QQV7 P35475 Q56A80 Q59H58	3W81[A,B] 2.30 3W82[A,B] α-L-IdopA 2.76 4JXO[A,B] 2.10 4JXP[A] 2.17 4KGJ[A,B] α-L-IdopA1F 2.99 4KGL[A,B] 2.70 4KH2[A,B] β-L-IdopA2F-(1-4)-GLU 2.36 4MJ2[A,B] 2.10 4MJ4[A] 2.17 4OBR[A,B] α-L-IdopA 2.46 4OBS[A] 2.26 6I6R[A,B] 2.02 6I6X[A,B] 2.39
α-L-(β-1,2)-arabinofuranobiosidase (NF2152)		Neocallimastix frontalis	ASF57707.1	A0A218MY43 A0A247D6Y4	5U22[A] 1.75
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